DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8176 and gas7a

DIOPT Version :9

Sequence 1:	NP_001097723.1	Gene:	CG8176 / 261329	FlyBaseID:	FBgn0037702	Length:	1220	Species:	Drosophila melanogaster
Sequence 2:	NP_001265748.1	Gene:	gas7a / 793701	ZFINID:	ZDB-GENE-130128-1	Length:	344	Species:	Danio rerio

Alignment Length:	279	Identity:	71/279 - (25%)
Similarity:	130/279 - (46%)	Gaps:	32/279 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DYFWGEKNN-------GYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKL------AHK 58
            ||||.:|.:       |::||......|....||::||:||:..|||:.:|.:|||      |.:
Zfish    70 DYFWTDKRDLQGATVTGFEVLLQKQLKGKQMQKEMAEFIRERIKIEEEYAKNLSKLSMFPMAAQE 134

  Fly    59 AGTLNSTFAPVWTILRTSAEKLSTLHLQMVQKL-TELVKDVAKYADELHKKHKSVKEEESQTLEC 122
            .|||..    .|..|:.|....:.:||:...|| :|:.|.:..:..:..|  |.:|:.:....:.
Zfish   135 EGTLGE----AWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLTFRGDNFK--KDMKKYDHHIADL 193

  Fly   123 VQAIQTSTVAVQKLRDLYASKVQELE------KLRKDNGSHKDAEKLESKLKKLQEEYKALLDKH 181
            .:.:.:...||:|.|...|.:.::||      :::..|.|.:|.:|...|..:..::....:|.:
Zfish   194 RKQLVSRYAAVEKARKALADRQKDLEVKTQQLEIKLSNKSEEDIKKARRKSTQAGDDLMRCVDLY 258

  Fly   182 NPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQ---VHSDFKRQFVDMS 243
            |..::::...|..|....:::|...:..:::.|..| ..|::..||..|   ...|...|.||.:
Zfish   259 NQAQSKWFEEMVTTSMELEKLEVERIEMIQQHLRQY-TTLRHETDMFNQSTLEPVDQLLQSVDPA 322

  Fly   244 VDKLLEQFVLNKYTGLEKP 262
            .|:  |.:|....||..:|
Zfish   323 KDR--ELWVKEHKTGDRRP 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	67/275 (24%)
		Apolipoprotein	52..214	CDD:279749	36/174 (21%)
		AP_Syp1_like_MHD	928..1194	CDD:271171
gas7a	NP_001265748.1	WW_FCH_linker	<21..69	CDD:293229
gas7a	NP_001265748.1	F-BAR_GAS7	81..314	CDD:153333	56/239 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810