DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8176 and pstpip1b

DIOPT Version :9

Sequence 1:	NP_001097723.1	Gene:	CG8176 / 261329	FlyBaseID:	FBgn0037702	Length:	1220	Species:	Drosophila melanogaster
Sequence 2:	NP_001032668.1	Gene:	pstpip1b / 641582	ZFINID:	ZDB-GENE-051127-25	Length:	379	Species:	Danio rerio

Alignment Length:	358	Identity:	63/358 - (17%)
Similarity:	140/358 - (39%)	Gaps:	90/358 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KELSEFLREKSNIEEQNSKMMSKLAHKA------GTLNSTFAPVWTILRTSAEKLSTLHLQMVQK 90
            |::.|.|:.::..||:..:.:..:|.||      |||.::|..    .:...||...||:|:.::
Zfish     3 KDVEELLKMRALAEEKYGRDLVAIARKAEGQTEIGTLKASFDK----FKEEIEKTGNLHIQLSER 63

  Fly    91 LTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVAVQK----LRDLYASKVQELE--- 148
            :.|.|..:     |:.::|:  :|:..:..|.::.:|...:.:.|    .:.||..:.:|.:
Zfish    64 IKEEVLKI-----EVFREHQ--REQRKKLEEIIEKLQKPKMVLHKKTMESKRLYEQRCKEADESE 121

  Fly   149 -----KLRKDNGSHKDAEKLESKLK-------KLQEEYKALLDKHNPIKNEFERRMTQTCKRFQE 201
                 |...:..:|:.:||:.::.:       ..:::|:..:|:......::|......|:.||:
Zfish   122 QALGKKTNVNTSTHRQSEKVMNRARLCRQAANLAEKQYRWNVDQLGKTCQDWESTYRSACEVFQQ 186

  Fly   202 IEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQ---------FVLNKYT 257
            .|...:..::..|..:..:|..........:.:         |.|:|||         |:..|.|
Zfish   187 QESERINILRCVLWEHCNLLSKQCVQDDDCYEE---------VRKILEQCDIVADNNNFIKMKKT 242

  Fly   258 GLEKPEMPELEYVALSSGS------RLQQPQVSA-----------SASNSNSATSIQAALRAG-- 303
            ....|  ..:|:...|...      |::..::|.           .|||::.|.......|.|
Zfish   243 SSHPP--APIEFQCYSDADTNGGVRRIETNRLSVVLSGMSFSGFPEASNNSGAKYTPDQQRIGVT 305

  Fly   304 ---------------NAATTASGSAVSMDQRGD 321
                           :..:.:.|..|::.::|:
Zfish   306 EEKYMVLYEFKAQEDDELSISKGQVVTITEKGE 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	50/270 (19%)
		Apolipoprotein	52..214	CDD:279749	34/186 (18%)
		AP_Syp1_like_MHD	928..1194	CDD:271171
pstpip1b	NP_001032668.1	BAR	1..225	CDD:299863	43/241 (18%)
pstpip1b	NP_001032668.1	SH3_PSTPIP1	308..360	CDD:212758	3/31 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910