Protein Alignment CG8176 and fcho1

DIOPT Version :9

• Sequence 1: NP_001097723.1
• Gene: CG8176 / 261329
• FlyBaseID: FBgn0037702
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: NP_001184127.1
• Gene: fcho1 / 493195
• XenbaseID: XB-GENE-5946032
• Length: 906
• Species: Xenopus tropicalis
• Alignment Length: 1209
• Identity: 314/1209 - (25%)
• Similarity: 499/1209 - (41%)
• Gaps: 326/1209 - (26%)

  Fly     5 FNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAH--KAGTLNSTFA 67
            |.::|||:||:|:.|||||||.|.::.|||::|:||::.|||..||.|.||:.  .:|:...|||
 Frog     4 FGEHFWGDKNSGFAVLYHNMKHGQLSVKELADFVRERAAIEESYSKSMQKLSKMVSSGSHLGTFA 68

  Fly    68 PVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVA 132
            |:|.:.|.|::||:..||::.:||.:|:||:::|.||..|.||..|:|.|.|||.:|.:|.::..
 Frog    69 PMWEMFRVSSDKLALCHLELSKKLHDLIKDISRYGDEQIKMHKKSKDEMSGTLEAIQLLQCNSQM 133

  Fly   133 VQKLRDLYASKVQELEKLRKDNGSHKDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCK 197
            :||.||.|.:|..|.|:||::....|:.||.|.|.:|..:..:..::|:|.::.|||::|.|:.:
 Frog   134 LQKSRDNYCTKFSEQERLRREGSLQKELEKAELKTRKAADSLRCSVEKYNAVRKEFEQKMLQSAQ 198

  Fly   198 RFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKP 262
            .||:.|..|||.||..::.|...:::.|..:||||.:||....:::|:||:.:|..:..||.::|
 Frog   199 TFQDTEATHLRHMKRLVTAYSHSVEDTHVQIGQVHEEFKHNMENVAVEKLIRRFAESNGTGTDRP 263

  Fly   263 EMPELEYVALSSGSRLQQPQVSASASNSNSATSIQAALRAGNAATTASGSAVSMDQRGDALAAIS 327
            |..|.|      |.|..
 Frog   264 EPVEYE------GFRFP------------------------------------------------ 274

  Fly   328 LGSGSAASGSIPFAEDPILGAMGSPRPTSPDMLAGANASGIQSQPTGGATSTVKSLRSWFLPTAK 392
                                               |:..|::              |:|..|
 Frog   275 -----------------------------------ASLEGVK--------------RTWSKP--- 287

  Fly   393 QQPSAGAGNFGMAGSGSTNNTTTTTTASNNSNNLNTNNTTATTTTTTGTNNLTTNITKNSPNSED 457
                     |.:.|. |..........|:..:.:|..:......|....:||..|..:...:|:
 Frog   288 ---------FRIRGL-SRREKEAHPLESSELDCMNHPDVDEEGFTIRPDDNLNRNSVQCCSSSD- 341

  Fly   458 TSNQDQTQQQPAEALTPTASATAIAAASAPGKKQLNATTSEQQLSKSLNEQEHLQQTAAATAATT 522
             |:.|...::|                     :::.......|:|:::.:||
 Frog   342 -SDFDDDGEEP---------------------RRIRFQIKPPQISENVEDQE------------- 371

  Fly   523 AAATTATTTTSRRATSLLNIFTSNSQVSGILRSRRDKTKTKKAKKKKDNEAAENIQEERLTSLDR 587
                   |...|...|:..|....|.|..:.|                    .||:......:..
 Frog   372 -------TEMKRLRESVECILQPPSAVVSVRR--------------------HNIRTAGAVDVSS 409

  Fly   588 GNNTLLDYDDHGRSMKTQNSSGSSAGGGLAALSVTSAQGSVDSAGASSMGGSGGAAVASGSLPNA 652
            |:..:|:..:                         .|..|:.....||:..|           :.
 Frog   410 GDPQILNQTE-------------------------KAAESLSDTPPSSLTSS-----------DT 438

  Fly   653 GALTNSASITAPGAASGTGTGYEVDEEGFSIQPAKEIAWEEGQDKSGSFYSDSDTDSDNDKQERR 717
            .::.:|.|:..|...|                               .|.||..|...|
 Frog   439 NSVNHSQSLFGPLLES-------------------------------LFESDDFTGCRN------ 466

  Fly   718 IHVSIKPLKNGQAPMSASVDELRATVENISL-SPTGVFSHHSQQLQAARGAPASRQQSPEISNAS 781
                 ..|.:..:|.|:|..|   .||:..| ||...||..|         |.||..:|. .:.|
 Frog   467 -----CTLTSSPSPFSSSSPE---NVEDSGLDSPFHPFSGPS---------PDSRPWTPR-DDVS 513

  Fly   782 TPTASVHPYAPLQSPTLSNNNNANNTTNSRYADLGDIFSELGDM----------SMSAPSSATLG 836
            |..:           .|:..:.|.:.::|..|.:    :|||..          |:||....||.
 Frog   514 TGDS-----------LLAARSCAESPSDSEIAPV----TELGKKNASEQRVCAPSISASDYTTLS 563

  Fly   837 KPPGRQIPTPTSASTGGSIAIPRPPS----RRSDMIA-IGPAATGTAPGRGRMSPAPVTAMNRAE 896
            ..........:..|.|.::::|.|.:    |.|:|.| :.|:.         ::|...::::...
 Frog   564 TTEQSSCEADSWDSPGYNLSLPPPTAPRLQRSSNMTASLNPSL---------LTPGVCSSVHNDR 619

  Fly   897 SIGSLEFRTAIG-GVGSSRGPSPLTIGISDTIPLAVAFHEIIHAYFRGSDESRCQVKVSGDMMLS 960
              |...|...:| .:|.||||||:.: ..:::|:|.||.|.:||.|.|.......:::||::.:|
 Frog   620 --GLSPFSLGVGTSLGLSRGPSPVILXSQESLPVAAAFTEYVHAVFEGGALEGSSLRISGELTMS 682

  Fly   961 FPAGIAGLLANNPNPAKLGFRIKHVQNLENLVPNGKLVQIDRQQSSSVSTMLEFNMGALTALLRR 1025
            |||||..:.|:...|..|.||:.|..::|:..||.:|:..|..||...|.....||..||:.|..
 Frog   683 FPAGILRVFASTATPPVLSFRLIHTSHVEHFAPNSELLFSDLSQSDPNSRDFWLNMPGLTSYLNN 747

  Fly  1026 QAENNPTASYFNVDILKYQVRTKPGASSCPFQLVSYWKCESSYTALKVDYKYNNHAMASASPLLN 1090
            .||.: .|.|:||.:||||| .|.|.|:.|..|.|.|||..|.|.|.:||:.|      .:.|.:
 Frog   748 MAEQH-AAPYYNVTLLKYQV-LKSGISAAPLYLTSTWKCGPSSTDLCLDYRQN------IAFLCD 804

  Fly  1091 VTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLELNDGPSTPALLA 1155
            |.:.:|::....|:||.|.:..  ...||.|........::..|.|.:.||.:....||.|....
 Frog   805 VQILLPLDEPFSNLQSDPPARC--AERRLHWQIPHEPAGNEHDGWGRICARWQPLHAPSRPTSAV 867

  Fly  1156 TQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKY-VC 1193
            .||..||:||||::.||.|||||:||||:||.:||| ||
 Frog   868 AQFTSEGSTLSGVDIELVGSGYRMSLVKKRFAAGKYLVC 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	105/259 (41%)
		Apolipoprotein	52..214	CDD:279749	65/163 (40%)
		AP_Syp1_like_MHD	928..1194	CDD:271171	105/267 (39%)
fcho1	NP_001184127.1	F-BAR_FCHO1	10..270	CDD:153358	106/265 (40%)
		FCHo1_MHD	650..906	CDD:271173	103/265 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	202	1.000	Domainoid score	I2934
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	565	1.000	Inparanoid score	I1067
OMA	1	1.010	-	-		QHG45895
OrthoDB	1	1.010	-	-		D286007at33208
OrthoFinder	1	1.000	-	-		FOG0001508
OrthoInspector	1	1.000	-	-		otm72283
Panther	1	1.100	-	-	LDO	PTHR23065
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1233
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080