Protein Alignment CG8176 and Sgip1

DIOPT Version :10

• Sequence 1: NP_001097723.1
• Gene: CG8176 / 261329
• FlyBaseID: FBgn0037702
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: NP_001363865.1
• Gene: Sgip1 / 313413
• RGDID: 1564957
• Length: 855
• Species: Rattus norvegicus
• Alignment Length: 883
• Identity: 245/883 - (27%)
• Similarity: 372/883 - (42%)
• Gaps: 281/883 - (31%)

  Fly   559 KTKTKKA----KKKKDNEAAENIQEERLTSLDRGNNTLLDYDDHGRSMKTQNSSGSSAGGGLAAL 619
            |.:|:||    ||:||.::..:...:.:    :|..         ::.|||....|..  .|.||
  Rat     6 KKRTRKAFGIRKKEKDTDSTGSPDRDGM----QGKK---------KAQKTQLLLTSCF--WLRAL 55

  Fly   620 SVTSAQGSV-------DSAGASSMGGSGGAAVASGSLPNAGALTNSASITAPGAASGTGTGYEVD 677
            |:|.:|...       ..|..:..||...:..::|:.....|..:.....:|          |:|
  Rat    56 SLTLSQQPSPHEPPYHSKAECAREGGKKASKKSNGAPNGFYAEIDWERYNSP----------ELD 110

  Fly   678 EEGFSIQPAKEIAWEEGQDKSGSFYSDSDTDSDNDKQERRIHVSIKPLKNGQA-PMSASVDELRA 741
            |||:||:|.     |.|..|...|||.|::: :.::..::.::.||||::... ..:|:||||:|
  Rat   111 EEGYSIRPE-----EPGSTKGKHFYSSSESE-EEEESHKKFNIKIKPLQSKDVLKNAATVDELKA 169

  Fly   742 TVENISLSPT----------GVFSHHSQQLQAARGAPASRQQSPEISNAST-------------- 782
            ::.||:|||:          |....:....:.||  |.....:||:::...
  Rat   170 SIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVAR--PRRSTPTPELTSKKPLDDTLALAPLFGPP 232

  Fly   783 ---------------------------------------PTASVHPYAPLQSP----------TL 798
                                                   ||.:..|..|...|          |:
  Rat   233 LESAFDEQKTEVLLDQPEIWGSGQPINPSMESPKLARPFPTGTPPPLPPKAVPATPPRTGSPLTV 297

  Fly   799 SNNNNANNTTNS-----RYADLGDIFSEL------------------------------------ 822
            :..|:...|...     ..:||..||..:
  Rat   298 ATGNDQAATEAKIEKLPSISDLDSIFGPVLSPKSVAVNTEEKWVHFSDASPEHVTPELTPREKVV 362

  Fly   823 -----GDMSMSAPSSATLGK--------PPG-RQIPTP----------------------TSAST 851
                 .|:...:|:....|.        ||| |.:|:|                      |.:|.
  Rat   363 TPPAASDIPADSPAPGPPGPPGSAGPPGPPGPRHVPSPLNLEEVQKKVAEQTFIKDDYLETLSSP 427

  Fly   852 G----GSIAI---PRPPSRRSDMIAIGP---AATGTA---------------------------- 878
            .    |..|.   |.||:.|:.:.:.||   :.||||
  Rat   428 KECGLGQRATPPPPPPPTYRTVVSSPGPGSGSGTGTASGASSPARPATPLVPCSSTTPPPPPPRP 492

  Fly   879 ----------PGRGRM-----------SPAPVTAMNRAESIGSLEFRTAIGGV------------ 910
                      ||.|.:           ||.|:..:.||||..|:....::...
  Rat   493 PSRPKLPPGKPGVGDVSRPFSPPIHSSSPPPIAPLARAESTSSISSTNSLSAATTPTVENEQPSL 557

  Fly   911 -------------GSSRGPSPLTIGISDTIPLAVAFHEIIHAYFRGSDESRCQVKVSGDMMLSFP 962
                         ||||||||||:|..||:|:|.||.|.::|||:|:|.|:|.||::|:|:||||
  Rat   558 VWFDRGKFYLTFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGADPSKCIVKITGEMVLSFP 622

  Fly   963 AGIAGLLANNPNPAKLGFRIKHVQNLENLVPNGKLVQIDRQQSSSVSTMLEFNMGALTALLRRQA 1027
            |||....||||:||.|.||:.:...||:::||.:|:..|..|:.:.:.....||..|...|::.:
  Rat   623 AGITRHFANNPSPAALTFRVINSSRLEHVLPNPQLLCCDNTQNDANTKEFWVNMPNLMTHLKKVS 687

  Fly  1028 ENNPTASYFNVDILKYQVRTKPGASSCPFQLVSYWKCESSYTALKVDYKYNNHAMASASPLLNVT 1092
            |..|.|:|:|||:|||||..: |..|.|..|...|:||...|.|::|||||..||.:|..|.||.
  Rat   688 EQKPQATYYNVDMLKYQVSAQ-GIQSTPLNLAVNWRCEPGSTDLRIDYKYNTDAMTTAVALNNVQ 751

  Fly  1093 LSVPVNGSVRNVQS-KPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLELNDGPSTPALLAT 1156
            ..||::|.|..:|: .|.:.|..|..|::|...||||.|::||||:|.||.:|::|||.|:.|..
  Rat   752 FLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKSENGGVGSLLARFQLSEGPSKPSPLVV 816

  Fly  1157 QFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1194
            ||..||:||||.:.||.|:|||.||:|:||.:|||:.:
  Rat   817 QFTSEGSTLSGCDIELVGAGYRFSLIKKRFAAGKYLAD 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332
		PHA03307	731..>921	CDD:223039	72/423 (17%)
		AP_Syp1_like_MHD	928..1194	CDD:271171	125/266 (47%)
Sgip1	NP_001363865.1	SGIP1_MHD	588..854	CDD:271172	125/266 (47%)