Protein Alignment CG8176 and Fcho2

DIOPT Version :9

• Sequence 1: NP_001097723.1
• Gene: CG8176 / 261329
• FlyBaseID: FBgn0037702
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: XP_038958075.1
• Gene: Fcho2 / 309129
• RGDID: 1565396
• Length: 876
• Species: Rattus norvegicus
• Alignment Length: 1233
• Identity: 352/1233 - (28%)
• Similarity: 512/1233 - (41%)
• Gaps: 452/1233 - (36%)

  Fly     5 FNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKAGTLN--STFA 67
            |.:.||||||||:||||||||.|.|::|||::|:||::.|||..|:.|:|||..|...:  .|||
  Rat    52 FVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFA 116

  Fly    68 PVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVA 132
            |||.:.:||.|||:..||.:|:||.||:|:|.||.:|..|.||..|||.:.|||.|||||..|.|
  Rat   117 PVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQA 181

  Fly   133 VQKLRDLYASKVQELEKLRKDNGSHKDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCK 197
            :||.::.|.:|..|.|:|:|:..:.::.||...|.||..:.||..::|:...|.:||::||:|.:
  Rat   182 LQKSKENYNAKCVEQERLKKEGATPREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQ 246

  Fly   198 RFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKP 262
            :||:|||.||..:||.:.:....::..|..:||||.:|.....:.:::.|:::|..:|.||.|:|
  Rat   247 KFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERP 311

  Fly   263 EMPELEYVALSSGSRLQQPQVSASASNSNSATSIQAALRAGNAATTASGSAVSMDQRGDALAAIS 327
                                                                             
  Rat   312 ----------------------------------------------------------------- 311

  Fly   328 LGSGSAASGSIPFAE-DPILGAMGSPRPTSPDMLAGANASGIQSQPTGGATSTVKSLRSWFLPTA 391
                    |.|.|.| ||                                .|.|:.::
  Rat   312 --------GLIEFEECDP--------------------------------ASAVEGIK------- 329

  Fly   392 KQQPSAGAGNFGMAGSGSTNNTTTTTTASNNSNNLNTNNTTATTTTTTGTNNLTTNITKNSPNSE 456
                                                                             
  Rat   330 ----------------------------------------------------------------- 329

  Fly   457 DTSNQDQTQQQPAEALTPTASATAIAAASAPGKKQLNATTSEQQLSKSLNEQEHLQQTAAATAAT 521
                                          |.|::..|
  Rat   330 ------------------------------PRKRKTFA--------------------------- 337

  Fly   522 TAAATTATTTTSRRATSLLNIFTSNSQVSGILRSRRDKTKTKKAKKKKDNEAAENIQEERLTSLD 586
                                       :.||:            ||:||.|:.|
  Rat   338 ---------------------------LPGII------------KKEKDAESVE----------- 352

  Fly   587 RGNNTLLDYDDHGRSMKTQNSSGSSAGGGLAALSVTSAQGSVDSAGASSMGGSGGAAVASGSLPN 651
                                                                          .|:
  Rat   353 --------------------------------------------------------------CPD 355

  Fly   652 AGALTNSASITAPGAASGTGTGYEVDEEGFSIQPAKEIAWEEGQDKSGSFYSDSDTDSDNDKQER 716
            |.      |:..|          :||||||||:|..    .:...|...|||.||:||: |::.:
  Rat   356 AD------SLNIP----------DVDEEGFSIKPEA----NQNDTKENHFYSSSDSDSE-DEEPK 399

  Fly   717 RIHVSIKPL-KNGQAPMSASVDELRATVENISLSPTGVFSHHSQQLQAARGAPASRQQSPEISNA 780
            |..:.|||: .|......||:|||:.::.||:|||  ..|.|| .:|..|.  :|.::..:...:
  Rat   400 RYRIEIKPVHPNNVHHTMASLDELKVSIGNITLSP--AVSRHS-PVQMNRN--SSNEELTKSKPS 459

  Fly   781 STPTA----SVHPYAPL--------QSPTLSNNNNANNTTNSRYADLGDIFSELGDMSMSAPSSA 833
            |.||.    .:..:.||        .:|..|::::|..||.   ..||.|.
  Rat   460 SLPTEKGTNDLLAWDPLFGSSLESSSAPLTSSSSSARPTTP---LSLGTIV-------------- 507

  Fly   834 TLGKPPGRQIPTP--TSASTGGSIAIPRPPSRRSDMIAIGPAATGTAPGRGRMSPAPVTAMNRAE 896
                ||.|....|  ||....|...||||         ..|..|...      ||.|...:.|||
  Rat   508 ----PPPRPASRPKLTSGKLSGINEIPRP---------FSPPITSNT------SPPPTAPLARAE 553

  Fly   897 SIGSLEFRTAIGGV-------------------------GSSRGPSPLTIGISDTIPLAVAFHEI 936
            |..|:....::...                         |.||||||:::|..||:|:|:|..|.
  Rat   554 SSSSISSSASLSAANTPTVEDDNLIGTLSEIEKHCETTPGVSRGPSPVSLGNQDTLPVAIALTES 618

  Fly   937 IHAYFRGSDESRCQVKVSGDMMLSFPAGIAGLLANNPNPAKLGFRIKHVQNLENLVPNGKLVQID 1001
            ::|||:|:|.::|.||::||:.:|||:||..:..:||:||.|.||:|::..||.::||.:||..|
  Rat   619 VNAYFKGADPTKCIVKITGDVTISFPSGIIKVFTSNPSPAVLCFRVKNISRLEQILPNSQLVFSD 683

  Fly  1002 RQQSSSVSTMLEFNMGALTALLRRQAENNPTASYFNVDILKYQVRTKPGASSCPFQLVSYWKCES 1066
            ..|..|.:.....||.|:|..|::.:|.||.|||:|||:|||||.:. |..|.|..|.:||||.:
  Rat   684 PSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSN-GIQSTPLNLATYWKCSA 747

  Fly  1067 SYTALKVDYKYNNHAMASASPLLNVTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQ 1131
            |.|.|:||||||..||.:.|.|.|:.:.|||:|.|.|:||.|.:.|..|..:..|..:.||:.|.
  Rat   748 STTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSGISEKSD 812

  Fly  1132 DGGVGTLRARLELNDGPSTPALLATQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1194
            .||.|:|||:.:|::|||.||.||.||..||.||||::.||.|:||||||||:||.:|:|:.:
  Rat   813 SGGSGSLRAKFDLSEGPSKPATLAVQFLSEGNTLSGVDIELVGTGYRLSLVKKRFATGRYLAD 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	114/259 (44%)
		Apolipoprotein	52..214	CDD:279749	75/163 (46%)
		AP_Syp1_like_MHD	928..1194	CDD:271171	129/265 (49%)
Fcho2	XP_038958075.1	F-BAR_FCHO2	51..319	CDD:153357	120/339 (35%)
		FCHo2_MHD	610..876	CDD:211378	129/267 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	269	1.000	Domainoid score	I1774
eggNOG	1	0.900	-	-		E1_KOG2398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	592	1.000	Inparanoid score	I940
OMA	1	1.010	-	-		QHG45895
OrthoDB	1	1.010	-	-		D286007at33208
OrthoFinder	1	1.000	-	-		FOG0001508
OrthoInspector	1	1.000	-	-		otm46360
orthoMCL	1	0.900	-	-		OOG6_104540
Panther	1	1.100	-	-	O	PTHR23065
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1233
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840