DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8176 and sfp47

DIOPT Version :9

Sequence 1:	NP_001097723.1	Gene:	CG8176 / 261329	FlyBaseID:	FBgn0037702	Length:	1220	Species:	Drosophila melanogaster
Sequence 2:	NP_593857.1	Gene:	sfp47 / 2542091	PomBaseID:	SPAC7D4.02c	Length:	415	Species:	Schizosaccharomyces pombe

Alignment Length:	404	Identity:	77/404 - (19%)
Similarity:	138/404 - (34%)	Gaps:	148/404 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 QTSTVAVQKLRDLYASKVQ-ELEKLRKDNGSHKDAEKLESKLKKLQEEYKALLDKHNPIKNEFER 190
            :.||.|:...:.|...::. |||              ..:||.||.:..||:  |.....|:..:
pombe    12 EISTEALNNWQQLVEQRISLELE--------------YAAKLAKLTKSIKAI--KQCAPLNDLTK 60

  Fly   191 RMTQTCKRFQEIEEVHLR-------QMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDK-- 246
               |.|....:..:.||.       .:|||:..|:               |.:.:|.:.::.|
pombe    61 ---QVCVELMQCNKKHLEASRYFQTHVKEFMKEYV---------------DRENKFSNETISKSS 107

  Fly   247 ------LLEQFVL-------NKYTGLEKPEMPELEYVALSSGSRLQQP-QVSASASNSNSATSIQ 297
                  .:|.|:|       ||   |:.|...::|   :::..::.|| :.::..:|..||.|::
pombe   108 AAALMTSMENFILFTNPVYHNK---LQVPSKSDME---IANSLKITQPAEKNSGTANPISAYSLE 166

  Fly   298 AALRAGNAATTASGSAVSMDQRGDALA-AISL-------------------GSGSAASGSIPFAE 342
            .|               .:|:|.:.|: |:|:                   |.....:..:..:.
pombe   167 HA---------------ELDERNNQLSEALSMLRLSPFVNNYYPSYQNRKDGKSLMENRGVVLSV 216

  Fly   343 DPILGAMGSPRPTSPDMLAGANASGIQSQPTGGATSTVKSLRSWFLPTAKQQPSAGAGNFGMAGS 407
            |.:.    ||...||..|.          ||   ||.:.|....|: .||:..|.....:..
pombe   217 DTVT----SPISQSPKKLT----------PT---TSPINSTSLSFV-DAKKPGSKWPSQYDF--- 260

  Fly   408 GSTNNTTTTTTASNNSNNLNTNNTTATTTTTTGTNNLTTNITKNS-----------PNSEDTSNQ 461
              ...|.:|........:||.||              ...:||:.           |:::.|::.
pombe   261 --PKKTKSTEIPFKTLPSLNINN--------------ERELTKHKLPIVKPKLAVFPSNQATAST 309

  Fly   462 DQTQQQPAEALTPT 475
            .|....|.:|: ||
pombe   310 LQLAPPPVQAI-PT 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	33/164 (20%)
		Apolipoprotein	52..214	CDD:279749	21/94 (22%)
		AP_Syp1_like_MHD	928..1194	CDD:271171
sfp47	NP_593857.1	BAR	12..>193	CDD:299863	46/235 (20%)
sfp47	NP_593857.1	SH3	356..411	CDD:214620
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47409
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000