Protein Alignment CG8176 and syp1

DIOPT Version :10

• Sequence 1: NP_001097723.1
• Gene: CG8176 / 261329
• FlyBaseID: FBgn0037702
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: NP_596299.1
• Gene: syp1 / 2540862
• PomBaseID: SPBC4C3.06
• Length: 818
• Species: Schizosaccharomyces pombe
• Alignment Length: 990
• Identity: 191/990 - (19%)
• Similarity: 336/990 - (33%)
• Gaps: 311/990 - (31%)

  Fly    34 LSEFLREKSNIEEQNSKMMSKLA-HKAGTLNSTFA--PVWTILRTSAEKLSTLHLQMV-QKLTEL 94
            ||:::||:.:||.|.|..:.||| :.....||:||  ..|..|.....::|..|.|:: |..:::
pombe    40 LSQWIRERMDIERQYSDQLHKLAMNMQEKNNSSFAFNYAWKQLEGETLEISRYHSQIIGQIASQV 104

  Fly    95 VKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVAVQKLRDLYASKVQELEKLRKDNGSHKD 159
            .|.:..|         .....::.||..: |.:.||||    .::.:|.|..|:.|:|..   :|
pombe   105 YKPLIDY---------YTSSPQTATLRRL-AERLSTVA----EEMASSSVPGLKGLKKKG---RD 152

  Fly   160 AEKLESKLKKLQEEY---KALLDKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEML 221
            |:      .|.|.:.   :|..|...|:..|          :.|.::|..|..:|:   .||.:.
pombe   153 AD------TKSQNDLTASRATWDSDAPLAFE----------KLQIVDEERLLILKQ---VYLTIA 198

  Fly   222 QNNHDMVGQVHSDFKRQ---FVDMSVDKLLEQFVLNKYTGLEKPEMPELEYVALSSGSRLQQPQV 283
            ....|...:....|.:.   :.|:.::..:.||:
pombe   199 SLETDTALKQQEFFSKSMAVYSDLPIEGEIRQFM------------------------------- 232

  Fly   284 SASASNSNSATSIQAALRAGNAATTASGSAVSMDQRGDALAAISLGSGSAASGSIPFAEDPILGA 348
                   ||.:.:.::..| |..:.:||              ..:.:|.
pombe   233 -------NSTSKVMSSASA-NKPSKSSG--------------FHINNGK---------------- 259

  Fly   349 MGSPRPTSPDMLAGANASGIQSQPTGGATSTVKSL--RSWFLPTAKQQP---SAGAGNFGMAGSG 408
                  :..:...|.|.||      |...:.:.:|  |...:|...::|   |.|..|...|...
pombe   260 ------SKEEKSHGENESG------GKLKNKMSTLFRRKTIMPKKDKKPSHKSNGRPNKLTAFFN 312

  Fly   409 STNNTTTTTTASNNSNNLN---------TNNTTATTTTTTGTNNLTTNITKNSPNSEDTSNQDQT 464
            ..:..::.::|..:.:|::         .:|.::.......|||..::....:..|::..:.|.|
pombe   313 KNSKASSISSAEEHPSNIDDSSIERRHYDSNHSSQIRDHPSTNNNASSYQNFNETSDEGEDNDAT 377

  Fly   465 QQ---------------QP---AEALTPTASATAIAAASAPGKKQLNATTSE--QQLSKSLNEQ- 508
            .:               ||   ||.:||..|:.|     :|..|. |:..||  :....|::.:
pombe   378 IRANNVRSSFLEAPLPVQPNVQAETVTPKISSKA-----SPFNKP-NSVHSEASRNTPSSIDREN 436

  Fly   509 ------------------EHLQQTAAATAATTAAATTATTTTSRRATSLLNIFTSNSQVSGILRS 555
                              .::|..:..|:.|:|.|:.|.|...          .||:.:..:..:
pombe   437 ASHSNPIMMHGNDFGGNFNNMQSRSTTTSPTSAVASPAPTENE----------DSNAAIERVANT 491

  Fly   556 -RRDKTKTKKAKKKKDNEAAENIQEERLTSLDRGNNTLLDYDDHGRSMKTQNSSGSSAGGGLAAL 619
             |::.|.:::.:              |..::||......||.:             |..|.|..|
pombe   492 LRKNPTISRRTR--------------RAGTMDRYATASSDYME-------------SNLGSLPNL 529

  Fly   620 SVTSAQGSVDSAGASSMGGSGGAAVASGSLPNAGALTNSASITAPGAASGTGTGYEVDEEGFSIQ 684
            |..|.|...||           .|......||:..|  ||||..  ..||     |:.|:|. :.
pombe   530 STLSLQSGPDS-----------TATWHPEFPNSSGL--SASIVE--KYSG-----ELSEDGL-LH 573

  Fly   685 PAKEIAWEEGQDKSGSFYSDSDTDSDNDKQERRIHVSIK-PLK----NGQAPMSASVDELRATVE 744
            |:          .||..:....:|.:....|..:.|:.: |:.    |..|......:...:.:.
pombe   574 PS----------CSGHIFMKYTSDFNTPPPEMGVRVASEFPMSFTHLNDHAVKYGPSENTLSLIP 628

  Fly   745 NISLSPTGV--FSHHSQQLQAARGAPAS-RQQSPEISNASTPTASVHPYAPLQSPTLSNNNNANN 806
            .:.|||..|  |:.|...:..|...|.: .|:.....::|:..|.|.|           |....|
pombe   629 ELLLSPIKVTDFNLHLDSINGASCIPLTVVQKWKHDESSSSMIAFVKP-----------NPVWRN 682

  Fly   807 TTNSRYADLGDIFSELGD--MSMSAPSSATLGKPPGRQIPTPTS-----------ASTGGSIAIP 858
            ..:|.:.:...|...||:  :..|..||      |..:....||           :|:|..|..
pombe   683 LGSSLHIEKLVIIVYLGENVLVKSCQSS------PAGEFSRKTSKLKLHLSNINISSSGFKILA- 740

  Fly   859 RPPSRRSDMIAIGPAATGTAP---GRGRMSPAPVTAMNRAESIGSLEFRTAIGGVGSSRGPSPLT 920
                    ..||.|:|....|   .|.||    |.:.|. ..:..|..:..:....||.|.|.|.
pombe   741 --------KFAISPSAAIRKPVIEFRIRM----VDSSNN-PGLTKLFLKPDMFDTTSSSGGSQLE 792

  Fly   921 IGISDT-IPLAVAFH 934
            ....:| :|.:...|
pombe   793 SAYEETKVPTSYGIH 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	54/244 (22%)
		PHA03307	731..>921	CDD:223039	44/208 (21%)
		AP_Syp1_like_MHD	928..1194	CDD:271171	2/7 (29%)
syp1	NP_596299.1	F-BAR_Syp1p_like	17..241	CDD:153334	56/274 (20%)
		AP_Syp1_MHD	553..814	CDD:271170	66/306 (22%)