DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8176 and pstpip2

DIOPT Version :9

Sequence 1:	NP_001097723.1	Gene:	CG8176 / 261329	FlyBaseID:	FBgn0037702	Length:	1220	Species:	Drosophila melanogaster
Sequence 2:	XP_009303409.1	Gene:	pstpip2 / 100537857	ZFINID:	ZDB-GENE-091204-90	Length:	331	Species:	Danio rerio

Alignment Length:	301	Identity:	64/301 - (21%)
Similarity:	130/301 - (43%)	Gaps:	66/301 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FNDYFWG---EKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKA------G 60
            |.|.||.   ....|||.:..::..|....||:.:|::.::.|||:.:|.:..|:.|.      .
Zfish     6 FKDNFWNTDITSTAGYDTIIQHLNDGKRTCKEIEDFMKARAAIEEKYAKELLGLSKKVCGHSEMN 70

  Fly    61 TLNSTFAPVWTILRTSAEKLSTLHLQMVQ--------------KLTELVKDVAKYADELHKK--- 108
            ||..:.    .:.:...|.:|..||.:.|              |..|..|.|.:..|.|||:
Zfish    71 TLKRSL----DVFKLQTENMSLSHLHLAQTMREEAKKLEDFREKQKEARKKVEQQMDALHKQKAA 131

  Fly   109 --HKSVKEEESQTLECVQAIQT--------STVAVQKLRDLYASKVQELEKLRKDNGSHKDAEKL 163
              .|:.:.::|...:|....:|        :|.:.::...||| |.|:.::      :.::|:::
Zfish   132 QYKKTAEAKKSYDQKCRDKEETEQNMNRSATTCSAKQQEKLYA-KTQQAKQ------AAEEADRI 189

  Fly   164 ESK----LKKLQEEYKALLDKHNPIKNEFERRMTQTCKRFQEIEEVHLRQMKEFLSTYLEMLQNN 224
            .|:    |.|::||:   |::|           .:.|:.|::.|...:..::..:.|:|..|...
Zfish   190 YSQNVSVLGKMREEW---LNEH-----------VKACEFFEKQEVERINTLRNIVWTHLNHLSQQ 240

  Fly   225 HDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKPEMP 265
            .....:::.:.::.....::.:.:|.||..:.|| :||..|
Zfish   241 CVSSDEIYEEVRKSLEQCNIQEDIEHFVNLRRTG-DKPPAP 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	60/295 (20%)
		Apolipoprotein	52..214	CDD:279749	38/198 (19%)
		AP_Syp1_like_MHD	928..1194	CDD:271171
pstpip2	XP_009303409.1	BAR	15..253	CDD:299863	52/262 (20%)
pstpip2	XP_009303409.1	T3SSipB	55..192	CDD:293143	28/147 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578446
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2398
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740