Protein Alignment CG8176 and fcho2

DIOPT Version :10

• Sequence 1: NP_001097723.1
• Gene: CG8176 / 261329
• FlyBaseID: FBgn0037702
• Length: 1220
• Species: Drosophila melanogaster
• Sequence 2: NP_001135543.1
• Gene: fcho2 / 100216087
• XenbaseID: XB-GENE-943410
• Length: 812
• Species: Xenopus tropicalis
• Alignment Length: 1221
• Identity: 368/1221 - (30%)
• Similarity: 519/1221 - (42%)
• Gaps: 446/1221 - (36%)

  Fly     5 FNDYFWGEKNNGYDVLYHNMKFGLIASKELSEFLREKSNIEEQNSKMMSKLAHKAG--TLNSTFA 67
            |.:.||||||:|:||||||||.|.|::||||||:||:|.|||..|:.|:|||..|.  |...||.
 Frog     6 FLENFWGEKNSGFDVLYHNMKHGQISTKELSEFIRERSTIEEVYSRSMNKLAKSASNYTQLGTFG 70

  Fly    68 PVWTILRTSAEKLSTLHLQMVQKLTELVKDVAKYADELHKKHKSVKEEESQTLECVQAIQTSTVA 132
            |||.:.:||.|||:..||::|:||.:|:|:|.||.:|..|.||..|||.|.|||.||.||:.|.|
 Frog    71 PVWDVFKTSTEKLAGCHLELVKKLQDLIKEVQKYGEEQLKSHKKTKEEVSGTLEAVQNIQSITQA 135

  Fly   133 VQKLRDLYASKVQELEKLRKDNGSHKDAEKLESKLKKLQEEYKALLDKHNPIKNEFERRMTQTCK 197
            :.|.:|||.:|..|.|||:|:..:.|:.||...|.||..|.||..::|:...|.:||::||:|.:
 Frog   136 LHKAKDLYNAKCLEQEKLKKEGAAAKEIEKAAIKTKKATESYKICVEKYAAAKLDFEQKMTETAQ 200

  Fly   198 RFQEIEEVHLRQMKEFLSTYLEMLQNNHDMVGQVHSDFKRQFVDMSVDKLLEQFVLNKYTGLEKP 262
            :||:|||.||.::||.:.:|...:...|..:||||.||.....:::||.||::|..:|.||.|:|
 Frog   201 KFQDIEEAHLMRVKEIIESYSHSVSEVHIQIGQVHEDFINNMANITVDSLLQKFAESKGTGKERP 265

  Fly   263 EMPELEYVALSSGSRLQQPQVSASASNSNSATSIQAALRAGNAATTASGSAVSMDQRGDALAAIS 327
            ...|.|                    ..|:|..::
 Frog   266 GPIEFE--------------------ECNTAVVVE------------------------------ 280

  Fly   328 LGSGSAASGSIPFAEDPILGAMGSPRPTSPDMLAGANASGIQSQPTGGATSTVKSLRSWFLPTAK 392
                                                   |::.          |..:::.|||.
 Frog   281 ---------------------------------------GVKQ----------KKRKTFGLPTI- 295

  Fly   393 QQPSAGAGNFGMAGSGSTNNTTTTTTASNNSNNLNTNNTTATTTTTTGTNNLTTNITKNSPNSED 457
                                                                             
 Frog   296 ----------------------------------------------------------------- 295

  Fly   458 TSNQDQTQQQPAEALTPTASATAIAAASAPGKKQLNATTSEQQLSKSLNEQEHLQQTAAATAATT 522
                                                                             
 Frog   296 ----------------------------------------------------------------- 295

  Fly   523 AAATTATTTTSRRATSLLNIFTSNSQVSGILRSRRDKTKTKKAKKKKDNEAAENIQEERLTSLDR 587
                                                      .||:||.|:.||
 Frog   296 ------------------------------------------IKKEKDTESVEN----------- 307

  Fly   588 GNNTLLDYDDHGRSMKTQNSSGSSAGGGLAALSVTSAQGSVDSAGASSMGGSGGAAVASGSLPNA 652
                                                       |.|.|:           :||
 Frog   308 -------------------------------------------ADADSL-----------NLP-- 316

  Fly   653 GALTNSASITAPGAASGTGTGYEVDEEGFSIQPAKEIAWEEGQDKSGSFYSDSDTDSDNDKQERR 717
                                  .||:||:||:| :||   :...|...|||.||:|.|.| ..:|
 Frog   317 ----------------------AVDDEGYSIKP-EEI---QNYTKENHFYSSSDSDEDED-GPKR 354

  Fly   718 IHVSIKPLK--NGQAPMSASVDELRATVENISLSPTGVFSHHSQQLQAARGAPASRQQSPEISNA 780
            .||.|||::  ||.....||:|||:.::.||||||.                 .|||
 Frog   355 FHVEIKPVQPNNGAHNTMASLDELKVSIGNISLSPA-----------------VSRQ-------- 394

  Fly   781 STPTASVHPYAPLQSPTLSNNNNANNTTNSRYADLGDIFSEL---------GDMSMSAPSSATLG 836
                      :|.|...:|::.:.|.|..:..|:  .:.|:|         ...|.|..||::..
 Frog   395 ----------SPAQMNRISSSEDMNRTRLAGQAE--KVSSDLLAWDPLYGSSHESSSISSSSSTV 447

  Fly   837 KPPGRQIPTPTSASTGGSIAIPRPPSRRSDMIAIGPAATG-------------TAPGRGRMSPAP 888
            .||.|  || |..|.|..:..|||.||        |..|.             :.|.....||.|
 Frog   448 SPPAR--PT-TPLSVGSIVPPPRPVSR--------PKLTAAKLCGINEVPRPFSPPLTSNTSPPP 501

  Fly   889 VTAMNRAESIGSLEFRTAIGGV-----GSSRGPSPLTIGISDTIPLAVAFHEIIHAYFRGSDESR 948
            ..::.||||..|:....:|...     |.||||||:|:|..||:|:|||..|.::|||||:|.::
 Frog   502 SASLPRAESSSSISSSASISAANTPTFGISRGPSPVTLGNQDTLPVAVALSESVNAYFRGADPTK 566

  Fly   949 CQVKVSGDMMLSFPAGIAGLLANNPNPAKLGFRIKHVQNLENLVPNGKLVQIDRQQSSSVSTMLE 1013
            |.||::|:|.:|||:||..:..:||:||.|.||:|:...||.::||.:|:..|..||.:......
 Frog   567 CIVKITGEMTVSFPSGIIKVFTSNPSPAVLCFRLKNTSRLEQILPNNQLLYSDPSQSDNNCKDFW 631

  Fly  1014 FNMGALTALLRRQAENNPTASYFNVDILKYQVRTKPGASSCPFQLVSYWKCESSYTALKVDYKYN 1078
            .||.|:||.|::.:|.||:|||:|||||||||.:. |..|.|..|.:||||.||.|.:::|||||
 Frog   632 MNMQAVTAYLKKSSEQNPSASYYNVDILKYQVLSN-GIQSTPLNLATYWKCTSSTTDVRLDYKYN 695

  Fly  1079 NHAMASASPLLNVTLSVPVNGSVRNVQSKPHSAWLGESNRLVWNFTDISQNSQDGGVGTLRARLE 1143
            ..:||..|.|.||.:.|||:|.|.::||.|.:.|..|..:.:|..:.||:.|::||.|:|||:.:
 Frog   696 PESMAMPSILSNVQVLVPVDGGVTSMQSLPSAIWNAEQMKALWKVSVISEKSENGGAGSLRAKFD 760

  Fly  1144 LNDGPSTPALLATQFNCEGTTLSGIEFELQGSGYRLSLVKRRFVSGKYVCE 1194
            |:||||.|:.||.||..:|.||||::.||.|:||||||||:||.:|||:.|
 Frog   761 LSDGPSNPSTLAVQFVSDGCTLSGVDIELVGTGYRLSLVKKRFGTGKYMAE 811

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8176	NP_001097723.1	F-BAR_FCHO	11..269	CDD:153332	125/259 (48%)
		PHA03307	731..>921	CDD:223039	58/216 (27%)
		AP_Syp1_like_MHD	928..1194	CDD:271171	131/265 (49%)
fcho2	NP_001135543.1	F-BAR_FCHO2	5..273	CDD:153357	129/286 (45%)
		FCHo2_MHD	546..812	CDD:211378	132/267 (49%)