Protein Alignment PRPF31 and Prpf31

DIOPT Version :10

• Sequence 1: NP_056444.3
• Gene: PRPF31 / 26121
• HGNCID: 15446
• Length: 499
• Species: Homo sapiens
• Sequence 2: NP_081604.3
• Gene: Prpf31 / 68988
• MGIID: 1916238
• Length: 499
• Species: Mus musculus
• Alignment Length: 499
• Identity: 494/499 - (98%)
• Similarity: 496/499 - (99%)
• Gaps: 0/499 - (0%)

Human     1 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMM 65
            |||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||
Mouse     1 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKSIAKLWDSKMFAEIMM 65

Human    66 KIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVP 130
            ||||||||||..|||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 KIEEYISKQANVSEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVP 130

Human   131 NALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMAL 195
            ||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||
Mouse   131 NALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSDEELERLEEACDMAL 195

Human   196 ELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLS 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 ELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLS 260

Human   261 GFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIE 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 GFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIE 325

Human   326 RKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQE 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 RKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQE 390

Human   391 DLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFT 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   391 DLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFT 455

Human   456 PLQGLEIVNPQAAEKKVAEANQKYFSSMAEFLKVKGEKSGLMST 499
            ||||||||||||||||||||||||||||||||||||||||.|||
Mouse   456 PLQGLEIVNPQAAEKKVAEANQKYFSSMAEFLKVKGEKSGTMST 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRPF31	NP_056444.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		35/35 (100%)
		Nop	100..330	CDD:460335	228/229 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..357		22/22 (100%)
		Prp31_C	337..465	CDD:462898	127/127 (100%)
		Nuclear localization signal (NLS). /evidence=ECO:0000269|PubMed:12444105	351..364		12/12 (100%)
Prpf31	NP_081604.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		41/41 (100%)
		Nop	100..330	CDD:460335	228/229 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..357		22/22 (100%)
		Prp31_C	337..465	CDD:462898	127/127 (100%)
		Nuclear localization signal (NLS). /evidence=ECO:0000250|UniProtKB:Q8WWY3	351..364		12/12 (100%)