DRSC/TRiP Functional Genomics Resources

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Protein Alignment LRIT1 and DIP-eta

DIOPT Version :9

Sequence 1:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens
Sequence 2:NP_001188701.2 Gene:DIP-eta / 33793 FlyBaseID:FBgn0031725 Length:450 Species:Drosophila melanogaster


Alignment Length:320 Identity:67/320 - (20%)
Similarity:112/320 - (35%) Gaps:93/320 - (29%)


- Green bases have known domain annotations that are detailed below.


Human   268 GGTALLRCGATGVPGPEMSWRRANGRPLNGTVHQEVSS-DGTSWTLLGLPAVSHLDSGDYICQAK 331
            |....|:|.|||.|.|.::|||.:|.|:.....:||.| :||.   |.:|.|.....|.|:|.|.
  Fly   161 GSNVTLKCAATGSPEPTITWRRESGVPIELATGEEVMSIEGTD---LVIPNVRRHHMGAYLCIAS 222

Human   332 NFLGASETV---ISLIVTEPPTSTEHSGSPGAL--------------------WARTGG-----G 368
            |  |...:|   |:|:|..||..|..:...||:                    |.|..|     |
  Fly   223 N--GVPPSVSKRITLVVHFPPMITVQNQLIGAVEGKGVTLDCESEAYPKSINYWTRERGEIVPPG 285

Human   369 G-------EAAAYNNKLVARHVPQIPKPAVLATGPSVPSTKEEL-TLEHFQMDALGELSDG---- 421
            |       |...|.|.: ..|:.              |.|:.|. :......::||: :||    
  Fly   286 GKYSANVTEIGGYRNSM-RLHIN--------------PLTQAEFGSYRCVAKNSLGD-TDGTIKL 334

Human   422 -RAGPSEARMVRSVKVVGDTYHSVSLVWKAPQAKNTTAFSVLYAVFGQHSMRRVIVQPGKTRVTI 485
             |..|:....|.:.:.            :....|.|.:....:....|......:..|||.:..:
  Fly   335 YRIPPNAVNYVENFEA------------RHKGKKRTKSSESHHPARAQEHSGEDMENPGKRKADL 387

Human   486 TGLLPKTKYVACVCVQGLVPRKEQCVIFSTNEVVDAENTQQLINVVVISVAIVIALPLTL 545
            :        :....:..:.          .|....:...|.|..|:::.:.:.:|:.::|
  Fly   388 S--------LGAESIDSIY----------GNSAAGSRRRQDLGGVLLLLLPVAVAVAMSL 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 30/80 (38%)
IG_like 267..345 CDD:214653 30/80 (38%)
FN3 431..498 CDD:214495 7/66 (11%)
LRR 6. /evidence=ECO:0000305 571..594
DIP-etaNP_001188701.2 Ig 51..141 CDD:299845
IG_like 51..137 CDD:214653
IG_like 153..237 CDD:214653 30/80 (38%)
Ig 161..224 CDD:299845 26/67 (39%)
IG_like 252..335 CDD:214653 17/98 (17%)
Ig 258..333 CDD:143165 16/90 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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