Protein Alignment ABHD12 and Bem46

DIOPT Version :10

• Sequence 1: XP_054179303.1
• Gene: ABHD12 / 26090
• HGNCID: 15868
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_477372.1
• Gene: Bem46 / 44441
• FlyBaseID: FBgn0025109
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 76/305 - (24%)
• Similarity: 127/305 - (41%)
• Gaps: 62/305 - (20%)

Human    61 ALGRRKGVWLR-LRKILFCVLGLYIAIPFL-IKLCPGIQAKLIFLNFVRVPYFIDLKK------- 116
            ||.:.:||.:. |...|.|.:..|....:: :.|..||...:.:.....:.|..||..
  Fly     7 ALPKSRGVGVGVLAAFLLCFIFYYFYGGYMTLALFAGIILLIFYYAQDLLLYHPDLPANSRIYIP 71

Human   117 -PQDQGLNHTCNYYLQPEEDVTI-GVWHTVPAVWWKNAQGKDQMWYEDALASSHPIILYLHGNAG 179
             |....|.| ....::..:|||: ..|.|.|                :..:.|.|.:||.|||||
  Fly    72 IPTMHNLPH-ITVSIKTPDDVTLHAFWVTQP----------------EERSKSSPTLLYFHGNAG 119

Human   180 TRGGDHRVE-LYKVLSSLGYHVVTFDYRGWGDSVGTPSERGMTYDALHVFDWIKARS--GDNPVY 241
            ..|  ||:: ::.:...|..:|:..:|||:|.|.|.|:|||:..||....|::..|.  ..:.:.
  Fly   120 NMG--HRMQNVWGIYHHLHCNVLMVEYRGYGLSTGVPTERGLVTDARAAIDYLHTRHDLDHSQLI 182

Human   242 IWGHSLGTGVATNLV-------RRLCERETPPDALILESPFTNIREEAKS--HPFSVIYRYFPGF 297
            ::|.|||..|..::.       :.:|        .|:|:.|::|.|.|..  ||   ..:|.|..
  Fly   183 LFGRSLGGAVVVDVAADTVYGQKLMC--------AIVENTFSSIPEMAVELVHP---AVKYIPNL 236

Human   298 DWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGR 342
              .|.:       |:.:...:...|.|.|.:....|.:||.::.|
  Fly   237 --LFKN-------KYHSMSKIGKCSVPFLFISGLADNLVPPRMMR 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABHD12	XP_054179303.1	FrsA	132..344	CDD:440691	59/224 (26%)
Bem46	NP_477372.1	FrsA	73..312	CDD:440691	62/239 (26%)