DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Or19b and Or43b

DIOPT Version :9

Sequence 1:	NP_728315.1	Gene:	Or19b / 260693	FlyBaseID:	FBgn0062565	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_523656.2	Gene:	Or43b / 35743	FlyBaseID:	FBgn0026393	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	452	Identity:	105/452 - (23%)
Similarity:	187/452 - (41%)	Gaps:	126/452 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LVNHWRIFRIMGIHP-PGKRTFWGRHYTAYSM-------------------VWNV---TFHICIW 53
            :..|:::     ::| |.......|...||.|                   :|.|   |:::.|.
  Fly     1 MFGHFKL-----VYPAPISEPIQSRDSNAYMMETLRNSGLNLKNDFGIGRKIWRVFSFTYNMVIL 60

  Fly    54 -VSFSVN------------LLQSNS--LETFCESLCVTMPHTLYMLKLINVRRMRGEMISSHWLL 103
             |||.:|            ||||..  |.|:|.:|       .:...::...|:  |:.:.|:
  Fly    61 PVSFPINYVIHLAEFPPELLLQSLQLCLNTWCFAL-------KFFTLIVYTHRL--ELANKHF-- 114

  Fly   104 RLLDKRLGC---ADERQI--IMAGIERAEFIFRTIFRGLACTVVLGIIYISASSEPTLM-----Y 158
            ..|||.  |   |::|::  ::|.|.|....|          ||:.::|.:::....|:     |
  Fly   115 DELDKY--CVKPAEKRKVRDMVATITRLYLTF----------VVVYVLYATSTLLDGLLHHRVPY 167

  Fly   159 PTWIPW-NWK-DSTSAYLATAMLHTTA----LMANATLVLNLSSYPGTYLILVSVHTKALALRVS 217
            .|:.|: ||: |.|..|:.:.:.:.|.    .:|.||     .|||..|:..:..|...|..|:.
  Fly   168 NTYYPFINWRVDRTQMYIQSFLEYFTVGYAIYVATAT-----DSYPVIYVAALRTHILLLKDRII 227

  Fly   218 KLG----YGAPLPAVRMQAILVGYIHDHQIILRLFKSLERSLSMTCFLQFFSTACAQCTICYFLL 278
            .||    .|:..|:...:: ||..|..|:.:|....:::..:|.|.|.||.        ||..:|
  Fly   228 YLGDPSNEGSSDPSYMFKS-LVDCIKAHRTMLNFCDAIQPIISGTIFAQFI--------ICGSIL 283

  Fly   279 FGNVGIM------------RFMNMLFLLVILTTETLLLCYTAEL---PCKEGESLLTAVYSCNWL 328
                ||:            ||..:::::.:| .:|..||:....   .|||   |..|::...|.
  Fly   284 ----GIIMINMVLFADQSTRFGIVIYVMAVL-LQTFPLCFYCNAIVDDCKE---LAHALFHSAWW 340

  Fly   329 SQSVNFRRLLLLMLARCQIPMILVSGVIVPISMKTFTVMIKGAYTMLTL---LNEIRKTSLE 387
            .|...::|.::..|.:.|.||...:..|..|::.|...:.|.|:|:..:   :|..:|.|::
  Fly   341 VQDKRYQRTVIQFLQKLQQPMTFTAMNIFNINLATNINVAKFAFTVYAIASGMNLDQKLSIK 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Or19b	NP_728315.1	7tm_6	65..372	CDD:251636	81/343 (24%)
Or43b	NP_523656.2	7tm_6	95..384	CDD:251636	78/333 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468660
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21137
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940