Protein Alignment vas and DDX18

DIOPT Version :9

• Sequence 1: NP_001260458.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_006764.3
• Gene: DDX18 / 8886
• HGNCID: 2741
• Length: 670
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 144/520 - (27%)
• Similarity: 248/520 - (47%)
• Gaps: 76/520 - (14%)

  Fly   105 GGSRGGQGG-SRGGQGGFRGGEGGFRGRLYENEDGDERRGRLDREERGGERRGRLDREERGGERG 168
            |.|....|| |:...|..:..:...:..:..|.:...:....:.:::..::|..::..|...::.
Human    64 GLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKKA 128

  Fly   169 ERGDGGFARRRRNEDDINNNNNIVEDVERKREFYIPPEPSNDAIEIFSSGIASGIHFSKYNNIPV 233
            :..:.|.:.....|......||:             .:|.||..|            |:..::|:
Human   129 KTENKGKSEEESAETTKETENNV-------------EKPDNDEDE------------SEVPSLPL 168

  Fly   234 KVTGSDVPQPIQHFTSADLRDIIIDN----VNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSG 294
            .:||:     .:..:.|.|.:::.:|    :.:.|:...|.||..||..:..||||:|.|:||||
Human   169 GLTGA-----FEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSG 228

  Fly   295 KTAAFLLP---ILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGT 356
            ||.|||:|   ::.||...|.    ....|:|:|||||||:|.|...::.........|::.||:
Human   229 KTLAFLIPAVELIVKLRFMPR----NGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGS 289

  Fly   357 SFRHQNECITRGCHVVIATPGRLLDFVDRT--FITFEDTRFVVLDEADRMLDMGFSEDMRRIMTH 419
            :...:.:.:..|.::::||||||||.:..|  |: :::.:.:|:|||||:||:||.|::::|:..
Human   290 NRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFM-YKNLQCLVIDEADRILDVGFEEELKQIIKL 353

  Fly   420 VTMRPEHQTLMFSATFPEEIQRMAGEFLKN---YVFV----AIGIVGG------ACSDVKQ--TI 469
            :..|  .||::||||...:::.:|...||.   ||.|    |...|.|      .|...|:  .:
Human   354 LPTR--RQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLL 416

  Fly   470 YEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRD 534
            :...|..::.||           :||..:.....:....|:..:.|..:|||.:.|::|......
Human   417 FTFLKKNRKKKL-----------MVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQ 470

  Fly   535 FKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGR--ATSFFDPEK 597
            |.|.....|:.|.||:|||||..:..::.||.|....:|:||:|||.| |.|||  |.....||:
Human   471 FCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGRGHALLILRPEE 534

  Fly   598  597
            Human   535  534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	78/222 (35%)
		DEXDc	260..467	CDD:214692	79/224 (35%)
		Helicase_C	475..584	CDD:278689	32/108 (30%)
DDX18	NP_006764.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..169		19/129 (15%)
		DEADc	179..386	CDD:238167	75/213 (35%)
		Q motif	179..207		6/27 (22%)
		DEXDc	194..382	CDD:214692	72/194 (37%)
		DEAD box	333..336		2/2 (100%)
		HELICc	400..529	CDD:238034	40/140 (29%)
		DUF4217	561..619	CDD:290667

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910