DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vas and DBP2

DIOPT Version :9

Sequence 1:	NP_001260458.1	Gene:	vas / 26067080	FlyBaseID:	FBgn0283442	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_014287.3	Gene:	DBP2 / 855611	SGDID:	S000005056	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	552	Identity:	201/552 - (36%)
Similarity:	309/552 - (55%)	Gaps:	52/552 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 YENEDGDERRGRLDREERGGERRGRLDREERGGERGERGDGGFARRRRNEDDINNNNNIVEDVER 197
            |::..||.|.|      |..:|....||.:.|..||  |.||.:...:.::.|..|.:  |::.:
Yeast    15 YKSRGGDFRGG------RNSDRNSYNDRPQGGNYRG--GFGGRSNYNQPQELIKPNWD--EELPK 69

  Fly   198 ----KREFYIPPEPSNDAIEIFSSGIASGIHFSKYNNIPVKVTGSDVPQPIQHFTSADLRDIIID 258
                ::.||:..|...|..:   |.||   .|.|.|.  :.::|.|:|:||..|..|...|.:::
Yeast    70 LPTFEKNFYVEHESVRDRSD---SEIA---QFRKENE--MTISGHDIPKPITTFDEAGFPDYVLN 126

  Fly   259 NVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRPQVVI 323
            .|...|:..||.||....|:..||||::..|.||||||.::.||.:..:...|.......|.|::
Yeast   127 EVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLV 191

  Fly   324 VSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFI 388
            ::||||||:||..|..||...|.::...||||.....|...::||..:||||||||:|.::....
Yeast   192 LAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIGKT 256

  Fly   389 TFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKNYVFV 453
            ..:...::|||||||||||||...:|:|:..:  ||:.||||:|||:|:|::::|.::|.:.:.|
Yeast   257 NLKRVTYLVLDEADRMLDMGFEPQIRKIVDQI--RPDRQTLMWSATWPKEVKQLAADYLNDPIQV 319

  Fly   454 AIGIVG-GACSDVKQTIYEVNKYAKRSKL---IEILSEQAD-GTIVFVETKRGADFLASFLSEKE 513
            .:|.:. .|..::.|.:..|:.:.||.:|   :|..|:..: .|::|..|||..|.:..:|.|..
Yeast   320 QVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDITKYLREDG 384

  Fly   514 FPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIG 578
            :|..:||||:.|.:|:..|::|:||...:::||.||:||:|:|.|.:|||||||..|:|||||||
Yeast   385 WPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIG 449

  Fly   579 RTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPDFL-----RTCGA---------GGDG 629
            ||||.|..|.|.||| .|:::.:.|.|:.|:..:.|.:|..|     |:.|.         ||.|
Yeast   450 RTGRAGATGTAISFF-TEQNKGLGAKLISIMREANQNIPPELLKYDRRSYGGGHPRYGGGRGGRG 513

  Fly   630 GYSNQ-NFGGVDVRGRGNYVGDATNVEEEEQW 660
            ||..: .:||    |||.|.|   |.:.:..|
Yeast   514 GYGRRGGYGG----GRGGYGG---NRQRDGGW 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	82/206 (40%)
		DEXDc	260..467	CDD:214692	82/207 (40%)
		Helicase_C	475..584	CDD:278689	52/112 (46%)
DBP2	NP_014287.3	PTZ00110	4..492	CDD:240273	185/497 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920