DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vas and AT2G42520

DIOPT Version :9

Sequence 1:	NP_001260458.1	Gene:	vas / 26067080	FlyBaseID:	FBgn0283442	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_001324553.1	Gene:	AT2G42520 / 818852	AraportID:	AT2G42520	Length:	633	Species:	Arabidopsis thaliana

Alignment Length:	599	Identity:	243/599 - (40%)
Similarity:	343/599 - (57%)	Gaps:	97/599 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 HGGRREGERDFRGGEGGFRGGQGGSR--GGQGGSRGGQGGFRGGEGGFRGRLYENEDGDERRGRL 145
            :||...|.|...||.|...||.||.|  .|:.||..|.|| ||| ||:..|
plant    56 YGGPPSGSRWAPGGSGVGVGGGGGYRADAGRPGSGSGYGG-RGG-GGWNNR-------------- 104

  Fly   146 DREERGGERRGRLDREERGGERGERGDGGFARRRRNEDDINNNNNIVEDVERKREFYIPPEPSND 210
                                      .||:.||.|..:...|:::             .|||:
plant   105 --------------------------SGGWDRREREVNPFENDDS-------------EPEPA-- 128

  Fly   211 AIEIFSSGIASGIHFSKYNNIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCS 275
                |:....:.|:|..|.:||::.:|.:||.|:..|...||.:.:..|:.:..|..|||:|:.:
plant   129 ----FTEQDNTVINFDAYEDIPIETSGDNVPPPVNTFAEIDLGEALNLNIRRCKYVKPTPVQRHA 189

  Fly   276 IPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPHELELGRPQ--------VVIVSPTRELAI 332
            ||::..||||||||||||||||||..||:|.:::|.|   :.||:        .||:|||||||.
plant   190 IPILLEGRDLMACAQTGSGKTAAFCFPIISGIMKDQH---VQRPRGSRTVYPLAVILSPTRELAS 251

  Fly   333 QIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVV 397
            ||.:||:||::::.:|:.:.||||....|...:.||..:::||||||.|.::|..::.:..||:.
plant   252 QIHDEAKKFSYQTGVKVVVAYGGTPINQQLRELERGVDILVATPGRLNDLLERARVSMQMIRFLA 316

  Fly   398 LDEADRMLDMGFSEDMRRIMTHVTMRPE--HQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGG 460
            ||||||||||||...:|:|:..:.|.|.  .|||:||||||.||||:|.:||.||:|:|:|.||.
plant   317 LDEADRMLDMGFEPQIRKIVEQMDMPPRGVRQTLLFSATFPREIQRLAADFLANYIFLAVGRVGS 381

  Fly   461 ACSDVKQTIYEVNKYAKRSKLIEILSEQADG--------TIVFVETKRGADFLASFLSEKEFPTT 517
            :...:.|.:..|....|||.|:::|..|.:.        |:||||||||||.|.::|....||.|
plant   382 STDLIVQRVEFVLDSDKRSHLMDLLHAQRENGIQGKQALTLVFVETKRGADSLENWLCINGFPAT 446

  Fly   518 SIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGR 582
            ||||||.|.:||.||:.||:|...:|:||.||:|||||.::.||:|:|:|:.|||||||||||||
plant   447 SIHGDRTQQEREVALKAFKSGRTPILVATDVAARGLDIPHVAHVVNFDLPNDIDDYVHRIGRTGR 511

  Fly   583 VGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPDFL-----RTCGAGGDGGYSNQNFGGVDVR 642
            .|.:|.||:||: :.:.::|..|.::::.:.|.||::|     |:...||....|...|||.|.|
plant   512 AGKSGLATAFFN-DGNTSLARPLAELMQEANQEVPEWLTRYASRSSFGGGKNRRSGGRFGGRDFR 575

  Fly   643 -------GRGNYVG 649
                   |||.|.|
plant   576 REGSFGSGRGGYGG 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	104/216 (48%)
		DEXDc	260..467	CDD:214692	104/216 (48%)
		Helicase_C	475..584	CDD:278689	64/116 (55%)
AT2G42520	NP_001324553.1	PTZ00110	13..558	CDD:240273	230/566 (41%)
AT2G42520	NP_001324553.1	DEADc_DDX3_DDX4	160..380	CDD:350725	106/222 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	51	1.000	Domainoid score	I4326
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000634
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100461
Panther	1	1.100	-	-	O	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920