DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vas and Ddx47

DIOPT Version :9

Sequence 1:	NP_001260458.1	Gene:	vas / 26067080	FlyBaseID:	FBgn0283442	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_080636.2	Gene:	Ddx47 / 67755	MGIID:	1915005	Length:	455	Species:	Mus musculus

Alignment Length:	362	Identity:	125/362 - (34%)
Similarity:	202/362 - (55%)	Gaps:	26/362 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 FTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDP 311
            |....:.|::.:..::.|:..||.||..:||:...|||::..|:||||||.||.||||:.|||.|
Mouse    26 FKDLGVTDVLCEACDQLGWAKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETP 90

  Fly   312 HELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATP 376
            ..|     ..::::||||||.||..:.........::..::.||.....|:..:.:..|:|||||
Mouse    91 QRL-----FALVLTPTRELAFQISEQFEALGSSIGVQCAVIVGGIDSMSQSLALAKKPHIVIATP 150

  Fly   377 GRLLDFVDRT-FITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQTLMFSATFPEEIQ 440
            |||:|.::.| .......:::|:|||||:|:|.|..::.:|:..:..  :.:|.:||||..:::|
Mouse   151 GRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPR--DRKTFLFSATMTKKVQ 213

  Fly   441 RMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKY-------AKRSKLIEILSEQADGT-IVFVE 497
            ::....|||.|..|:       |...||:.::.:|       .|.:.|:.||:|.|..: ::|..
Mouse   214 KLQRAALKNPVKCAV-------SSKYQTVEKLQQYYLFIPSKFKDTYLVYILNELAGNSFMIFCS 271

  Fly   498 TKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVI 562
            |.......|..|....|....:||...||:|..:|..||..:..:|:||.||||||||.::..|:
Mouse   272 TCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVV 336

  Fly   563 NYDMPSKIDDYVHRIGRTGRVGNNGRATSF---FDPE 596
            |:|:|:...||:||:|||.|.|.:|:|.:|   :|.|
Mouse   337 NFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	72/207 (35%)
		DEXDc	260..467	CDD:214692	72/207 (35%)
		Helicase_C	475..584	CDD:278689	43/116 (37%)
Ddx47	NP_080636.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		PRK11192	24..446	CDD:236877	125/362 (35%)
		Q motif	24..52		6/25 (24%)
		DEADc	26..227	CDD:238167	72/207 (35%)
		DEAD box	174..177		2/2 (100%)
		HELICc	237..366	CDD:238034	46/128 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	412..455
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920