Protein Alignment vas and DDX27

DIOPT Version :9

• Sequence 1: NP_001260458.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001335116.2
• Gene: DDX27 / 55661
• HGNCID: 15837
• Length: 796
• Species: Homo sapiens
• Alignment Length: 527
• Identity: 157/527 - (29%)
• Similarity: 250/527 - (47%)
• Gaps: 97/527 - (18%)

  Fly   134 ENEDGDERRGRLDRE---ERGGERRGRLDREERGGERGERGDGGFARRRRNEDDINN-NNNI--- 191
            :.||.:.:.|:|::|   :.|.|.:.:.|.:|...|..|        ...:|.|.:: :.||
Human    98 KTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSE--------DEASETDYSSADENILTK 154

  Fly   192 -----VEDVERKREFYIPPEPSNDAIEIFSSGIASGIHF---SKYN-NIPVKVTGSDVPQPIQHF 247
                 |:|.::|::                .|..:|..|   |:|: |:              .|
Human   155 ADTLKVKDRKKKKK----------------KGQEAGGFFEDASQYDENL--------------SF 189

  Fly   248 TSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPH 312
            ...:|...::..:...|:|.||||||..|||...|:|:.|||.||:||||||.||:|.:|:..|.
Human   190 QDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPR 254

  Fly   313 ELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATPG 377
            :..:.|  |:::.|||||.||:.:..|:.|....:...:..||...:.|...:.....::|||||
Human   255 QAPVTR--VLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPG 317

  Fly   378 RLLDFVDR-TFITFEDTRFVVLDEAD-------------------------------RMLDMGFS 410
            ||:|.:.. ..........::|||||                               ||||..|.
Human   318 RLIDHLHNCPSFHLSSIEVLILDEADSPPVDTAWPHAPTLWLLHLPFPQPGAISCPFRMLDEYFE 382

  Fly   411 EDMRRIMTHVTMRPEH-QTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEV-- 472
            |.|:.|   :.|...| ||::||||..:|::.:|...|||.|.:.:.........::|....:
Human   383 EQMKEI---IRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRP 444

  Fly   473 NKYAKRSKLIEILSEQ--ADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDF 535
            |:...|..::..|..:  .|..::|.:||:.|..:...|.........:||:..|:||.:|||.|
Human   445 NREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRF 509

  Fly   536 KNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRA 600
            |:..:.:|:||.||:|||||:.:|.|||:.||:.|..||||:|||.|.|..||:.|... |.:|.
Human   510 KDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVG-EDERK 573

  Fly   601 IAADLVK 607
            :..::||
Human   574 MLKEIVK 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	80/239 (33%)
		DEXDc	260..467	CDD:214692	78/239 (33%)
		Helicase_C	475..584	CDD:278689	43/110 (39%)
DDX27	NP_001335116.2	SrmB	188..674	CDD:223587	133/399 (33%)
		DEADc_DDX27	198..424	CDD:350705	78/230 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920