Protein Alignment vas and ddx4

DIOPT Version :10

• Sequence 1: NP_723899.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: XP_012818309.1
• Gene: ddx4 / 549577
• XenbaseID: XB-GENE-1016809
• Length: 678
• Species: Xenopus tropicalis
• Alignment Length: 707
• Identity: 306/707 - (43%)
• Similarity: 415/707 - (58%)
• Gaps: 75/707 - (10%)

  Fly     1 MSDDWDDE---------PIVDTRGARGGD----WSDDEDTAKSFSGEAEGDGVGGSGGEGGGYQG 52
            |.::||.|         |...:......|    :|:::.|.:::..|......||...|.||...
 Frog     1 MEENWDTEISTEKPTYIPNFSSLETDNTDNYTAYSNNDITNQNYQSERSFGNRGGYRSERGGPTN 65

  Fly    53 GNRDVFGRIGGGRGGGAG---GYR-GGNRDGGGFHGGRREGERDFRGGEGGFRGGQGGSRGGQGG 113
            .||.  .|||.|||..:.   .|. ...|||   :....:.::.|| |.||||...|..||
 Frog    66 FNRG--SRIGRGRGFDSNRNDQYSDSSERDG---YNANEDTQKPFR-GRGGFRNENGQRRG---- 120

  Fly   114 SRGGQGGFRGGEGGFRGRLYENEDGDER---RGRLDREERGGER-----RG---RLDREERG-GE 166
             .|.:||||            ||:|.:|   ||..:....|.||     ||   ..|.:..| |.
 Frog   121 -FGDRGGFR------------NENGQQRNFDRGDWNNSGEGEERPRGFGRGGFNNFDSDTGGRGH 172

  Fly   167 RGERGDGGFARRRRNEDDINNNNNIVEDVER--KREFYIPPEPSNDAIEIFSSGIASGIHFSKYN 229
            ||.||..|..:.|..|..:.:..|..|..|:  |:..|:|..||:...:||.. ..|||:|.||:
 Frog   173 RGGRGGRGGYKGRNEEVGVESGKNQEEGTEKEVKKVIYVPLPPSDSEDDIFRH-YQSGINFDKYD 236

  Fly   230 NIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSG 294
            .|.|.|||.|||..|..|..|:..:.:..||.|:||...||:||.|||:|.:|||||||||||||
 Frog   237 EILVDVTGKDVPPAILTFEEANFCETLSRNVTKAGYVKLTPVQKHSIPIILAGRDLMACAQTGSG 301

  Fly   295 KTAAFLLPILSKLLED----PHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGG 355
            |||||||||||.::.:    ...|.|..||.:|::|||||..||:.:||||::.:.::..:||||
 Frog   302 KTAAFLLPILSHMMNEGITASQFLPLQEPQAIIIAPTRELINQIYLDARKFSYGTCVRPVVVYGG 366

  Fly   356 TSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHV 420
            ....|....:.|||:::.||||||:|.:.|..|.....:::|||||||||||||:..|..::...
 Frog   367 IHPVHAMRDVERGCNILCATPGRLMDIIGREKIGLSKLKYLVLDEADRMLDMGFAPVMENLIGSP 431

  Fly   421 TM--RPEHQTLMFSATFPEEIQRMAGEFLK-NYVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLI 482
            .|  :.|.||||||||:|.||||:|.:||| :::||.:|:||||||||:|||.|:.:|.||.||:
 Frog   432 GMPAKEERQTLMFSATYPAEIQRLASKFLKSDHLFVVVGLVGGACSDVEQTILEIQEYRKRDKLV 496

  Fly   483 EILSEQADG---TIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLI 544
            |||  |:.|   |::||.||:.||.:|.:|.::.||||||||||.|.|||:|:|||::|...|::
 Frog   497 EIL--QSSGNERTMIFVNTKKKADVIAGYLCQEHFPTTSIHGDREQCQREEAIRDFRSGKCPVIV 559

  Fly   545 ATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKIL 609
            .|:||:|||||:|::||||||:|.:||:||||||||||.||.|:|||||:..:|..:|..|||||
 Frog   560 CTAVAARGLDIENVQHVINYDVPKEIDEYVHRIGRTGRCGNVGKATSFFNVNEDHVVARPLVKIL 624

  Fly   610 EGSGQTVPDFLRTCGAGGDGG----YSNQNFGGVDVRGRGNYVGDATNVEEEE-QWD 661
            ..:.|.||.:|.....||.|.    |:..:.||   .....||...::.:||| .||
 Frog   625 TDAHQEVPAWLEEIAFGGHGALNSLYAADSMGG---EAGEKYVSAPSSAQEEEASWD 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_723899.1	SrmB	247..617	CDD:440279	203/379 (54%)
ddx4	XP_012818309.1	DEADc_DDX4	210..473	CDD:350810	129/263 (49%)
		SF2_C_DEAD	479..608	CDD:350174	78/130 (60%)