DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vas and bel

DIOPT Version :9

Sequence 1:	NP_001260458.1	Gene:	vas / 26067080	FlyBaseID:	FBgn0283442	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_001262379.1	Gene:	bel / 45826	FlyBaseID:	FBgn0263231	Length:	801	Species:	Drosophila melanogaster

Alignment Length:	699	Identity:	301/699 - (43%)
Similarity:	409/699 - (58%)	Gaps:	101/699 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RGGDWSDDEDTAKSFSGEAEGDGVGGSGGEGGGYQGGN-----RDVFGRIGGG----RGGGAGGY 72
            |||..:::       :.:||..|.|...|:|...:.||     ||.....|||    ||||.||
  Fly    52 RGGGGNNN-------AADAESQGQGQGQGQGFDSRSGNPRQETRDPQQSRGGGGEYRRGGGGGG- 108

  Fly    73 RGGNRDGGGF-----HGGRREG----ERDFRGGEGGFRGGQGG----SRGGQGGSRG-GQG-GFR 122
            ||.||..|.:     .||||.|    |.::.|||  |...:||    |.||.||.|| |:| .:|
  Fly   109 RGFNRQSGDYGYGSGGGGRRGGGGRFEDNYNGGE--FDSRRGGDWNRSGGGGGGGRGFGRGPSYR 171

  Fly   123 GGEGGFRGRLYEN--EDGDERRGRLDREER--GGERRGRLDREERG---------GERGERGDGG 174
            ||.||....|.|.  |||..::.:..|.:|  ..||....|..|.|         ..|||||.||
  Fly   172 GGGGGSGSNLNEQTAEDGQAQQQQQPRNDRWQEPERPAGFDGSEGGQSAGGNRSYNNRGERGGGG 236

  Fly   175 FARRRRNEDDINNNNNIVEDVERKREFYIPPEPSNDAIEIFSSGIASGIHFSKYNNIPVKVTGSD 239
            :..|.:.....|.:...:...:.:.|           :|:|..| .:||:|.||.:|||:.||.:
  Fly   237 YNSRWKEGGGSNVDYTKLGARDERLE-----------VELFGVG-NTGINFDKYEDIPVEATGQN 289

  Fly   240 VPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPIL 304
            ||..|..|....|.:||.:||..:.|..|||:||.:||:|.:|||||||||||||||||||:|||
  Fly   290 VPPNITSFDDVQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPIL 354

  Fly   305 SKLLEDPH--------------ELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGG 355
            :::.|..|              :..||    ::::||||||.|||.||:|||:.|.::..::|||
  Fly   355 NQMYELGHVPPPQSTRQYSRRKQYPLG----LVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGG 415

  Fly   356 TSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHV 420
            .:...|...:.||||:::||||||.|.:.|..:..|:.||:|||||||||||||...:|||:..:
  Fly   416 NNTSEQMRELDRGCHLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQL 480

  Fly   421 TMRP--EHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIE 483
            .|.|  :.||||||||||::||.:|.:||.||:|:|:|.||....::.|||..|.:..|||.|::
  Fly   481 NMPPTGQRQTLMFSATFPKQIQELASDFLSNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLD 545

  Fly   484 ILSEQADG--------TIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSM 540
            :||...||        |::|||||:|||.|..||.:...|.|||||||.|.:||:|||.|::|..
  Fly   546 LLSSIRDGPEYTKDSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDC 610

  Fly   541 KVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADL 605
            .:|:||:||:|||||.::|||||:|:||.:::||||||||||:||.|.|||||: ||:|.|.:||
  Fly   611 PILVATAVAARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFN-EKNRNICSDL 674

  Fly   606 VKILEGSGQTVPDFL------------RTCGAGGDGGYSNQNFGGVDVR 642
            :::|..:.|.:|.|:            :..|.||.|.|.. .||..|.|
  Fly   675 LELLIETKQEIPSFMEDMSSDRGHGGAKRAGRGGGGRYGG-GFGSRDYR 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	111/222 (50%)
		DEXDc	260..467	CDD:214692	110/222 (50%)
		Helicase_C	475..584	CDD:278689	64/116 (55%)
bel	NP_001262379.1	DEADc	297..516	CDD:238167	111/222 (50%)
		DEXDc	315..529	CDD:214692	109/217 (50%)
		Helicase_C	538..654	CDD:278689	64/115 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451552
Domainoid	1	1.000	51	1.000	Domainoid score	I4326
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	280	1.000	Inparanoid score	I100
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000634
OrthoInspector	1	1.000	-	-		mtm9764
orthoMCL	1	0.900	-	-		OOG6_100461
Panther	1	1.100	-	-	P	PTHR47958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900