DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vas and ddx49

DIOPT Version :9

Sequence 1:	NP_001260458.1	Gene:	vas / 26067080	FlyBaseID:	FBgn0283442	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_938179.1	Gene:	ddx49 / 386632	ZFINID:	ZDB-GENE-031030-3	Length:	468	Species:	Danio rerio

Alignment Length:	388	Identity:	140/388 - (36%)
Similarity:	202/388 - (52%)	Gaps:	41/388 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 FTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDP 311
            |.|..|.:.:|....:.|...||.:|:..||.|..|||.|.||:|||||||||:||:|.||.|||
Zfish     4 FESLGLSEWLIQQCKQMGISRPTAVQEKCIPAILDGRDCMGCAKTGSGKTAAFVLPVLQKLSEDP 68

  Fly   312 HELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATP 376
            :.:     ..::::||||||.||..:.|.......||..|:.||.....|...:::..|||:|||
Zfish    69 YGV-----FCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVTQGLELSKKPHVVVATP 128

  Fly   377 GRLLDFV-DRTFITFEDTRFVVLDEADRMLDMG---FSEDMRRIMTHVTMRPEHQTLMFSATFPE 437
            |||.|.: ....|.....:|:::|||||:|:.|   |::|:..|::.|..:  .|||:||||..:
Zfish   129 GRLADHIRSSDTINLNRIQFLIMDEADRLLEQGCTDFTKDLEVILSAVPAK--RQTLLFSATLTD 191

  Fly   438 EIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVN----------KYAKRSKLIEILSEQAD-- 490
            .:|::....:....|      ....||| ||:.|::          |.|....||:...::.|
Zfish   192 TLQQLQSIAMNRPFF------WEHKSDV-QTVEELDQRFILTPEKVKDAYLVHLIQTFQDEHDDW 249

  Fly   491 GTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDI 555
            ..|:|..|.:....|...|.|..|||.|:|....|.||...|..||:...|:||||.||:|||||
Zfish   250 SIIIFTNTCKSCQILTMMLREFNFPTISLHSMMKQRQRFANLAKFKSNVFKILIATDVAARGLDI 314

  Fly   556 KNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSF---FDPEKDRAIAADLVKILEGSGQT 615
            ..::.|||::.|.....|:||:|||.|.|.||.:.:.   :|        ..|:..:|...||
Zfish   315 PTVQVVINHNTPGLPKIYIHRVGRTARAGRNGVSITLVTQYD--------IHLINAIEEQNQT 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	81/210 (39%)
		DEXDc	260..467	CDD:214692	80/210 (38%)
		Helicase_C	475..584	CDD:278689	44/110 (40%)
ddx49	NP_938179.1	PRK11192	3..415	CDD:236877	140/388 (36%)
		DEADc	4..206	CDD:238167	80/208 (38%)
		HELICc	218..351	CDD:238034	49/132 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920