Protein Alignment vas and ddx18

DIOPT Version :9

• Sequence 1: NP_001260458.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001003411.1
• Gene: ddx18 / 321127
• ZFINID: ZDB-GENE-030131-9685
• Length: 653
• Species: Danio rerio
• Alignment Length: 658
• Identity: 154/658 - (23%)
• Similarity: 272/658 - (41%)
• Gaps: 186/658 - (28%)

  Fly   134 ENEDGDERRGRLDREERGGERRGRLDREERGGERGERGDGGFARRRRNEDDINNNNNIVEDVERK 198
            |.|:.:|.:..||..|...:....:..|:               ::...|::|..:...:..::|
Zfish    31 EEENSEEVKDVLDESEVASDSAPNVIEEQ---------------QQSVSDEVNETSQKPKKKKKK 80

  Fly   199 REFYIPPEPSNDAIE------IFSSGIASGIHFSKY-------------NN-------------- 230
            |:.....|.:..:::      :.::..::|....:.             ||
Zfish    81 RKLDATGESTTSSVKKAKKQSVDTTQASAGEEEQQEEGNLETVKCPENGNNEKEGSAEEDSDEDG 145

  Fly   231 --IPVKVTGSDVPQPIQHFTSADLRDIIIDN----VNKSGYKIPTPIQKCSIPVISSGRDLMACA 289
              :|..:||:     .:..:.|.|.:::.:|    |.:.|:...|.||..:|..:..|||::|.|
Zfish   146 PQLPSGLTGA-----FEDRSFASLSEVVSENTLKGVKEMGFDTMTEIQHKTIRPLLEGRDVLAAA 205

  Fly   290 QTGSGKTAAFLLP---ILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGI 351
            :||||||.|||:|   ::.||...|.    ....|:::|||||||:|.:...::.........|:
Zfish   206 KTGSGKTLAFLIPSIELIYKLKFMPR----NGTGVIVLSPTRELAMQTYGVLKELMTHHVHTYGL 266

  Fly   352 VYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRT--FITFEDTRFVVLDEADRMLDMGFSEDMR 414
            :.||::...:.:.:..|.::::||||||||.:..|  |: |::.:.:::|||||:|::||.|:::
Zfish   267 IMGGSNRSAEAQKLANGVNILVATPGRLLDHLQNTPGFM-FKNLQCLIIDEADRILEVGFEEELK 330

  Fly   415 RIMTHVTMRP-EHQTLMFSATFPEEIQRMAGEFLKN---YVFV--------AIGIVGG--ACSDV 465
            :|   :.:.| :.|:::||||...:::.:|...||.   ||.|        ..|:..|  .|...
Zfish   331 QI---IKLLPKKRQSMLFSATQTRKVEDLARISLKKEPLYVGVDDNKDTATVEGLEQGYVVCPSE 392

  Fly   466 KQ--TIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQR 528
            |:  .::...|..::.||           :||..:.....|....|:..:.|..:|||.:.|::|
Zfish   393 KRFLLLFTFLKKNRKKKL-----------MVFFSSCMSVKFHYELLNYIDLPVMAIHGKQKQTKR 446

  Fly   529 EQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGR--ATS 591
            ......|.|....:|:.|.||:|||||..:..::.:|.|....:|:||:|||.| |.|||  |..
Zfish   447 TTTFFQFCNADSGILLCTDVAARGLDIPEVDWIVQFDPPDDPKEYIHRVGRTAR-GINGRGHALL 510

  Fly   592 FFDPEK-------------------------------DRAI------------------------ 601
            ...||:                               |:.|
Zfish   511 ILRPEELGFLRFLKQAKVPLSEFEFSWTKISDIQSQLDKLIEKNYYLHKSAQEAYKSYVRAYDSH 575

  Fly   602 ---------AADLVKILEGSGQTVPDF------------LRTCGAGGDGGYSNQN-------FGG 638
                     ..||.|:....|..||.|            |...|.||..||....       |..
Zfish   576 SLKQIYNVETLDLPKVAMSFGFKVPPFVDLNVHSSKGVKLHKRGGGGGFGYQKSKNVHKAKIFKH 640

  Fly   639 VDVRGRGN 646
            |: :|:|:
Zfish   641 VN-KGKGD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	73/227 (32%)
		DEXDc	260..467	CDD:214692	73/225 (32%)
		Helicase_C	475..584	CDD:278689	32/108 (30%)
ddx18	NP_001003411.1	SrmB	160..646	CDD:223587	135/506 (27%)
		DEADc	161..368	CDD:238167	70/214 (33%)
		HELICc	382..511	CDD:238034	41/140 (29%)
		DUF4217	543..601	CDD:290667	7/57 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910