Protein Alignment vas and Ddx4

DIOPT Version :10

• Sequence 1: NP_723899.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: XP_063137794.1
• Gene: Ddx4 / 310090
• RGDID: 1308793
• Length: 743
• Species: Rattus norvegicus
• Alignment Length: 748
• Identity: 315/748 - (42%)
• Similarity: 426/748 - (56%)
• Gaps: 107/748 - (14%)

  Fly     3 DDWDDE----------PIVD----TRGARGGDWSDDEDTAKSFSGEAEGDGVGG-----SGGEGG 48
            :||:.|          |:.:    :.||.|    |..:...:.|.|.| ||..|     ..|...
  Rat    14 EDWEAEILKPHVSSYVPVFEKDKYSSGANG----DTFNRTSASSSEME-DGPSGRDHFMRSGFSS 73

  Fly    49 GYQGGNRDV-----------FGRIGGGRGGGAGGYRGGNRDGGGFHGGRREGERD-------FRG 95
            |...||||:           .|..|.|:|.|..|:.....:.|...|..:|...|       .||
  Rat    74 GRNLGNRDIGESSKRETTSTTGGFGRGKGFGNRGFLNNKFEEGDSSGFWKESTNDCEDTQTRSRG 138

  Fly    96 --GEGGFRGGQGGSRGGQGGSRGGQGGFRGGEGGF-RGR---LYENEDGDERRGRLDREERGGER 154
              ..||:..|......|. ..|||:|.|||..||| .||   .|:.:.|.:|.|.|     .|.|
  Rat   139 FSKRGGYPDGNDSEASGP-FRRGGRGSFRGCRGGFGLGRPNSEYDQDQGSQRGGGL-----FGSR 197

  Fly   155 R-----------GRLDR-EERGGERGERGDGGFARRRRNEDDI-----NNNNNIVE-----DVER 197
            :           |..|. :.|.|    .|.||:  :..||:.:     |:..:..|     |::.
  Rat   198 KPAASDSVQCFTGSGDTFQSRSG----NGRGGY--KGLNEEVVTGSGKNSWKSEAEGGESSDIQG 256

  Fly   198 KREFYIPPEPSNDAIEIFSSGIASGIHFSKYNNIPVKVTGSDVPQPIQHFTSADLRDIIIDNVNK 262
            .:..||||.|..|...||:. ..:||:|.||:.|.|:|:|.|.|..|..|..|:|...:.:|:.|
  Rat   257 PKVTYIPPPPPEDEDSIFAH-YQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAK 320

  Fly   263 SGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLED----PHELELGRPQVVI 323
            :||...||:||.|||::.:|||||||||||||||||||||||:.::.|    ....||..|:.:|
  Rat   321 AGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQEPECII 385

  Fly   324 VSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFI 388
            |:|||||..||:.|||||:|.:.::..::||||.|.|....|.:||:::.||||||:|.:.:..|
  Rat   386 VAPTRELINQIYLEARKFSFGTCVRAVVIYGGTQFGHSIRQIVQGCNILCATPGRLMDIIGKEKI 450

  Fly   389 TFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTM--RPEHQTLMFSATFPEEIQRMAGEFLK-NY 450
            ..:..:::|||||||||||||..:|:::::...|  :.:.|||:|||||||||||:|||||| ||
  Rat   451 GLKQVKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLLFSATFPEEIQRLAGEFLKSNY 515

  Fly   451 VFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIEILSEQAD-GTIVFVETKRGADFLASFLSEKEF 514
            :|||:|.|||||.||:|:|.:|.:|:||.||:|||....| .|:||||||:.|||:|:||.:::.
  Rat   516 LFVAVGQVGGACRDVQQSILQVGQYSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKI 580

  Fly   515 PTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGR 579
            .||||||||.|.:|||||.||:.|...||:|||||:|||||:|::||||:|:||.||:|||||||
  Rat   581 STTSIHGDREQREREQALGDFRCGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGR 645

  Fly   580 TGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVPDFLR--TCGAGGDGGYSNQNFGGV--D 640
            |||.||.|||.||||.|.|..:|..|||:|..:.|.||.:|.  ...:.....:||...|.|  .
  Rat   646 TGRCGNTGRAISFFDTESDNHLAQPLVKVLSDAQQDVPAWLEEIAFSSYAPPSFSNSTRGAVFAS 710

  Fly   641 VRGRGNYVG------------DATNVEEEEQWD 661
            |..|.|:.|            .|.|..::|.||
  Rat   711 VDTRKNFQGKNTLNTAGISSAQAPNPVDDESWD 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_723899.1	SrmB	247..617	CDD:440279	212/377 (56%)
Ddx4	XP_063137794.1	None