Protein Alignment vas and Ddx24

DIOPT Version :9

• Sequence 1: NP_001260458.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001152974.1
• Gene: Ddx24 / 27225
• MGIID: 1351337
• Length: 903
• Species: Mus musculus
• Alignment Length: 652
• Identity: 137/652 - (21%)
• Similarity: 231/652 - (35%)
• Gaps: 207/652 - (31%)

  Fly   131 RLYENEDGDERRGRL---DREERGGE-----RRGRLDREERGGERGERGDGGFARRRRNEDDINN 187
            ||:.:|:..:|:.:.   :.||..|:     ::.:| :::|...|...|...     :||.::..
Mouse   110 RLFSSEETKKRKAQAVSEEEEEEEGQSSSPKKKIKL-KKQRDAARAAEGAAA-----QNEYEVKA 168

  Fly   188 NNNIVEDVERKREFYIPPEPSNDAIEIF--------SSGIASGIHFSKYNNIPVKV-----TGSD 239
            :.               ||...:.....        |..:|......|.|....|:     |...
Mouse   169 SE---------------PEAQGEVTACSDQKVGGAKSESLAQAAPRKKKNKGKKKLDTFQSTSPK 218

  Fly   240 VPQPIQ-------HFTSADL---RDIIIDN-----VNKSGYKIPTPIQKCSI-PVISSGRDLMAC 288
            :|:..:       |...||:   ||:.:..     ::..|:..|||||..:: |.|....|::..
Mouse   219 LPKKSKKTWMAEVHDQKADVSAWRDLFVPKAVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGA 283

  Fly   289 AQTGSGKTAAFLLPILSKLLE---------------DPHELELG--------------------- 317
            |:||||||.||.:|::..:|:               .|.|:..|
Mouse   284 AETGSGKTLAFAIPMIHSVLQWHKMKAPPIPRSTGMPPREMRFGATAHLGSPCKDRTESGVLPEE 348

  Fly   318 ----------------------------------------------------------------- 317
                                                                             
Mouse   349 ARIETEAQPSDSGVQATPETSASASAQTLLVCDDDAGEGPSSLEEKPVPKQNEDGEEKFDAEQAG 413

  Fly   318 ------------------RPQV-VIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNE 363
                              ||.: ::::||||||||:.......|..:.:...|:.||.|.:.|..
Mouse   414 KLKQELCDQIAIYKVHPRRPLLGLVLTPTRELAIQVRQHIDAVAKFTGINTAILVGGMSTQKQQR 478

  Fly   364 CITRGCHVVIATPGRLLDFVDRT---FITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVT---M 422
            .:.|...:||||||||.:.|...   .......|.:|:||||||::.|...::.:::..:.   .
Mouse   479 MLNRHPEIVIATPGRLWELVKEKHPHLSNLRQLRCLVIDEADRMVEKGHFAELSQLLEMLNDSQY 543

  Fly   423 RPEHQTLMFSATF------------PEEIQRMAGEFLKNYVFVAIGIVG-----------GACSD 464
            .|..|||:||||.            .:.:::|......:.:...:|:.|           |....
Mouse   544 NPSRQTLVFSATLTLVHQAPARILHKKHVKKMDKTDKLDLLMQKVGMRGKPKVIDLTRNEGTVET 608

  Fly   465 VKQTIYEVNKYAKRSKLIEILSEQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQRE 529
            :.:|........|...|...|.:....::||..:......|:..|...:....::|....|.||.
Mouse   609 LTETKIHCETDEKDLYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDVMPLTLHACMHQKQRL 673

  Fly   530 QALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFD 594
            :.|..|......||:||.||:|||||..::|||:|.:|...:.|:||.|||.|..:.|.:.....
Mouse   674 RNLEQFARLQDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYIHRSGRTARAASEGLSLMLIG 738

  Fly   595 PE 596
            ||
Mouse   739 PE 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	71/353 (20%)
		DEXDc	260..467	CDD:214692	70/356 (20%)
		Helicase_C	475..584	CDD:278689	36/108 (33%)
Ddx24	NP_001152974.1	SrmB	238..787	CDD:223587	112/503 (22%)
		P-loop_NTPase	241..557	CDD:304359	68/315 (22%)
		Helicase_C	619..727	CDD:278689	35/107 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53695
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920