DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vas and SPAC1F5.10

DIOPT Version :9

Sequence 1:	NP_001260458.1	Gene:	vas / 26067080	FlyBaseID:	FBgn0283442	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	NP_592863.1	Gene:	SPAC1F5.10 / 2541602	PomBaseID:	SPAC1F5.10	Length:	394	Species:	Schizosaccharomyces pombe

Alignment Length:	391	Identity:	126/391 - (32%)
Similarity:	212/391 - (54%)	Gaps:	20/391 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 VKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTA 297
            |::|.|:....:..|...:|::.::..:...||:.|:.:|..:|..|..|||::|.||:|:||||
pombe     9 VELTTSEDVNAVSSFEEMNLKEDLLRGIYAYGYETPSAVQSRAIIQICKGRDVIAQAQSGTGKTA 73

  Fly   298 AFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQN 362
            .|.:.||..:     :|.:...|.:|:|||||||:||.|..........::.....||||..:..
pombe    74 TFSIGILQSI-----DLSVRDTQALILSPTRELAVQIQNVVLALGDHMNVQCHACIGGTSVGNDI 133

  Fly   363 ECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRPEHQ 427
            :.:..|.|||..||||:.|.:.|..:...:.:.::|||||.:|:.||.|.:..|..:  :.|..|
pombe   134 KKLDYGQHVVSGTPGRVTDMIRRRNLRTRNVKMLILDEADELLNQGFKEQIYDIYRY--LPPGTQ 196

  Fly   428 TLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVN----KYAKRSKLIEILS-E 487
            .::.|||.|:::..|..:|..|.|.:.:.........:||....|.    |:.....|.:.|: .
pombe   197 VVVVSATLPQDVLEMTNKFTTNPVRILVKRDELTLEGLKQYFIAVEKEEWKFDTLCDLYDTLTIT 261

  Fly   488 QADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATSVASRG 552
            ||   ::|..::|..|:|...:.|..|..||:||:..|.:|:..::||:.|:.:|||.|.:.:||
pombe   262 QA---VIFCNSRRKVDWLTEKMREANFTVTSMHGEMPQKERDAIMQDFRQGNSRVLICTDIWARG 323

  Fly   553 LDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGSGQTVP 617
            :|::.:..|||||:|:..::|:|||||:||.|..|.|.:|...|..|     :::.:|....||.
pombe   324 IDVQQVSLVINYDLPANRENYIHRIGRSGRFGRKGVAINFVTNEDVR-----ILRDIEQYYSTVI 383

  Fly   618 D 618
            |
pombe   384 D 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	69/206 (33%)
		DEXDc	260..467	CDD:214692	67/206 (33%)
		Helicase_C	475..584	CDD:278689	40/109 (37%)
SPAC1F5.10	NP_592863.1	PTZ00424	19..392	CDD:185609	123/381 (32%)
		DEADc	23..223	CDD:238167	69/206 (33%)
		HELICc	234..363	CDD:238034	47/131 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910