Protein Alignment vas and glh-4

DIOPT Version :10

• Sequence 1: NP_723899.1
• Gene: vas / 26067080
• FlyBaseID: FBgn0283442
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_491207.3
• Gene: glh-4 / 171941
• WormBaseID: WBGene00001601
• Length: 1156
• Species: Caenorhabditis elegans
• Alignment Length: 767
• Identity: 236/767 - (30%)
• Similarity: 335/767 - (43%)
• Gaps: 159/767 - (20%)

  Fly    15 GARGGDWSDDEDTAKSFSGEAEGDGVGGSGGEGG-GYQGGNRDVFGRIGGGRGGGA-GGYRG--- 74
            |.:.|.......||::.....|..|.||.....| |....|...||:...|.||.. .|:.|
 Worm   428 GLKAGFGGHRASTAENSGLPTETTGFGGKLPPAGFGASSSNESAFGQQSKGFGGATKNGFGGDSS 492

  Fly    75 ---GNRDGGGFHGGRREGERD----FRGGEGGFRGGQGGSRGGQGGSRGGQGGFRGGEGGFRGRL 132
               |.|| .||.|.:.:|..|    .:.|.|.|..|     ||...|..|..|| |....|....
 Worm   493 NSFGKRD-SGFGGPQDQGFGDTDAPSKSGLGSFNTG-----GGAVKSAFGAAGF-GSSSNFGNGN 550

  Fly   133 YENEDGDERRGRLDREERGGER---------RGRLDRE--------------ERGGE-------- 166
            ...|..|.:||..|    ||||         .|.:.:|              |:.|.
 Worm   551 TFGEPSDNQRGNWD----GGERPRGCHNCGEEGHISKECDKPKVPRFPCRNCEQLGHFASDCDQP 611

  Fly   167 RGERG-------DGGFA----------RRRRNEDDINNNNNIVEDVERKREFYIPPEPSNDAIEI 214
            |..||       :|.||          ...||   .....:..:|.:.:|....|.||.....|.
 Worm   612 RVPRGPCRNCGIEGHFAVDCDQPKVPRGPCRN---CGQEGHFAKDCQNERVRMEPTEPCRRCAEE 673

  Fly   215 FSSGI--------ASGIHFSKY---------------NN-----IPVKVTGSDVPQPIQHFTSAD 251
            ...|.        ..|.....|               ||     ...||..|.....|....|.|
 Worm   674 GHWGYECPTRPKDLQGNFLESYDFVFTPDDKMFEDAVNNDDKIDFDQKVVASTGKVEIPDMASFD 738

  Fly   252 ----LRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSKLLEDPH 312
                |...:.||:.:.....|||||:.|...|..|.|::|||.||||||.|||:|.:.||:|
 Worm   739 GFKILPQDLHDNLKRMKMNRPTPIQRASFFPIMHGNDVVACAHTGSGKTLAFLIPFVIKLME--- 800

  Fly   313 ELELGR--------PQVVIVSPTRELAIQIFNEARKFAFESYLKIGIVYGGTSFRHQNECITRG- 368
            |.|..|        |:::||:|||||..|.|..||:..:|:.||.|:.:||.| |:.|....|.
 Worm   801 EFEKDRDVTDEKPSPRLLIVAPTRELVNQTFTTARQLTYETGLKCGLAFGGYS-RNANVQHLRSF 864

  Fly   369 --CHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMG-FSEDMRRIMTHVTMRPEHQTLM 430
              .::::||.|||.|||:...::....:::||||||||:|.. |.|::.:|:.....|.: ||::
 Worm   865 SQLNILVATMGRLQDFVNAGEVSLSKMKYIVLDEADRMVDSNDFGEEVSKIIGSPGERTQ-QTVL 928

  Fly   431 FSATFPEEIQR-MAGEFLK-NYVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIEILS------- 486
            |||:|.|::|. ...:|:| .|..:.:...|.|...:.|.|..|.:..||..:.::|.
 Worm   929 FSASFSEDLQSDDLPKFVKEGYTMLQVDKFGTANEKIDQKILPVPRTEKRDAIYKLLGIDENTVT 993

  Fly   487 ------EQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIA 545
                  .:...|::||.:.:..|.||:.:|.....|.|:|..:.|.||::.|.||:.|..:.::|
 Worm   994 LLPDAPIEKQKTLIFVNSVKFCDTLAALISSAGVSTISMHSYQNQEQRDRTLDDFRRGKYQCMVA 1058

  Fly   546 TSVASRGLDIKNIKHVINYDMPSK--IDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKI 608
            ::|.:|||:|..:.||:|||||.|  .|:||:|||||||.|..|.:|:|.|.|.|..|...||.|
 Worm  1059 SNVCARGLNIAGLDHVVNYDMPDKNGFDEYVNRIGRTGRAGFTGTSTAFVDVENDTDIIPCLVSI 1123

  Fly   609 LEGSGQTVPDFLRTCGAGGDGGYSNQNFGGVDVRGRGNYVGDATNVEEEEQW 660
            |..:.:.||::| |.|||      :|..||.|..            |:|::|
 Worm  1124 LNEAKKEVPEWL-TEGAG------HQEEGGDDWN------------EQEQEW 1156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_723899.1	SrmB	247..617	CDD:440279	148/402 (37%)
glh-4	NP_491207.3	dermokine	<388..>590	CDD:455732	49/172 (28%)
		PTZ00368	572..685	CDD:173561	19/115 (17%)
		SrmB	734..1109	CDD:440279	140/379 (37%)