DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vas and ddx59

DIOPT Version :9

Sequence 1:	NP_001260458.1	Gene:	vas / 26067080	FlyBaseID:	FBgn0283442	Length:	661	Species:	Drosophila melanogaster
Sequence 2:	XP_031756897.1	Gene:	ddx59 / 100488709	XenbaseID:	XB-GENE-976229	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	395	Identity:	141/395 - (35%)
Similarity:	236/395 - (59%)	Gaps:	19/395 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 IPVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGK 295
            :.:.|.|:::.:||..|.......::..|:..:||::|||||...|||...|||::|.|.|||||
Frog   356 LSLSVHGNEMCKPIMEFDHCQFPPVLSSNIKAAGYEVPTPIQMQMIPVGLMGRDILASADTGSGK 420

  Fly   296 TAAFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFE-SYLKIGIVYGGTSFR 359
            |||||||.:.:.||     :...|..:|::||||||:||..:|::.... .:::..::.||....
Frog   421 TAAFLLPAIIRCLE-----KKDSPAALILTPTRELAVQIEGQAKELMRGIPHMRTALLVGGMPLP 480

  Fly   360 HQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSE---DMRRIMTHVT 421
            .|...:.:|..|:||||||||:.:.:..:...|.:.:::||||.||.|||.:   |:..::.|
Frog   481 PQIHRLKQGVQVIIATPGRLLEIIKQDSVNLGDLKILIVDEADTMLKMGFQQQVLDILEVVPH-- 543

  Fly   422 MRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVNKYAKRSKLIEILS 486
               :|||::.|||.|..|:....:.|::.|.:.:|.....|::|:|.:..|.:.:|:.||.|||:
Frog   544 ---DHQTILVSATIPAGIEAFTKQLLQDPVRITVGEKNQPCTNVRQIVLWVEEPSKKKKLFEILN 605

  Fly   487 EQ---ADGTIVFVETKRGADFLASFLSE-KEFPTTSIHGDRLQSQREQALRDFKNGSMKVLIATS 547
            :.   ....:|||:.:.|||.|:..:|: ......::|.|:.|.:|.:.|:....|...|:::|.
Frog   606 DSKLFQPPVLVFVDCRLGADLLSDAVSKITGLECVAMHSDKSQVERMKILQGLLQGEYDVVVSTG 670

  Fly   548 VASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSFFDPEKDRAIAADLVKILEGS 612
            |..||||:.|:|.|:|:||||.:|:|||:|||.||:|:.|.|.:|.: :.:|.:..||||.::.:
Frog   671 VLGRGLDLVNVKLVVNFDMPSSMDEYVHQIGRAGRLGHRGTAITFIN-KNNRNLFWDLVKRVQPT 734

  Fly   613 GQTVP 617
            |..:|
Frog   735 GSLLP 739

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vas	NP_001260458.1	DEADc	247..454	CDD:238167	77/210 (37%)
		DEXDc	260..467	CDD:214692	78/210 (37%)
		Helicase_C	475..584	CDD:278689	44/112 (39%)
ddx59	XP_031756897.1	PHA03247	<29..211	CDD:223021
ddx59	XP_031756897.1	PLN00206	217..759	CDD:215103	141/395 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910