DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment solo and DDX4

DIOPT Version :9

Sequence 1:	NP_001027274.2	Gene:	solo / 26067079	FlyBaseID:	FBgn0283440	Length:	1031	Species:	Drosophila melanogaster
Sequence 2:	NP_077726.1	Gene:	DDX4 / 54514	HGNCID:	18700	Length:	724	Species:	Homo sapiens

Alignment Length:	281	Identity:	66/281 - (23%)
Similarity:	86/281 - (30%)	Gaps:	123/281 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DDWDDE---------PIVDTRGARGGDWSDDEDTAKSFSGEAEGDGVGG-----SGGEGGGYQGG 53
            :||:.|         ||.: :....|:..|:.:...:.|.|.: ||...     ..|...|...|
Human     4 EDWEAEINPHMSSYVPIFE-KDRYSGENGDNFNRTPASSSEMD-DGPSRRDHFMKSGFASGRNFG 66

  Fly    54 NRDV----------------FGRIGGGRG--------GGAGGY--------------------RG 74
            |||.                .|:..|.||        |.:.|:                    ||
Human    67 NRDAGECNKRDNTSTMGGFGVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCEDNPTRNRGFSKRG 131

  Fly    75 GNRDGGGFHGG---RREGERDFRGGEGGF-----------------RGGQGGSR---------GG 110
            |.|||......   ||.|...|||..|||                 .||..|||         |.
Human   132 GYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRTGGLFGSRRPVLSGTGNGD 196

  Fly   111 QGGSRGGQGGFRGG---------------------EGGFRGRLYENEDAK-----ELPPIPSSCD 149
            ...||.|.|..|||                     |||      |:.|.:     .:||.|.. |
Human   197 TSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGG------ESSDTQGPKVTYIPPPPPE-D 254

  Fly   150 KDEVGA-FIDQLDLSKYTTSL 169
            :|.:.| :...::..||.|.|
Human   255 EDSIFAHYQTGINFDKYDTIL 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
solo	NP_001027274.2	None
DDX4	NP_077726.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..246		56/249 (22%)
		Interaction with RANBP9. /evidence=ECO:0000269\|PubMed:27622290	228..247		5/24 (21%)
		SrmB	260..>660	CDD:223587	5/16 (31%)
		Q motif	288..316
		DEAD box. /evidence=ECO:0000250\|UniProtKB:Q61496	446..449
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..724
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D595675at2759
OrthoFinder	1	1.000	-	-		FOG0000634
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010