Protein Alignment solo and laf-1

DIOPT Version :10

• Sequence 1: NP_001027274.2
• Gene: solo / 26067079
• FlyBaseID: FBgn0283440
• Length: 1031
• Species: Drosophila melanogaster
• Sequence 2: NP_001254859.1
• Gene: laf-1 / 190611
• WormBaseID: WBGene00002244
• Length: 708
• Species: Caenorhabditis elegans
• Alignment Length: 865
• Identity: 172/865 - (19%)
• Similarity: 253/865 - (29%)
• Gaps: 339/865 - (39%)

  Fly    34 EAEGDGVGGSG----GEGGGY-----QGGNRDVFGRIGGG----RGG-GAGGY-RGGNRDGGGFH 83
            |:.....||||    ..||.|     :||:.........|    ||| |.||| |||...|||..
 Worm     2 ESNQSNNGGSGNAALNRGGRYVPPHLRGGDGGAAAAASAGGDDRRGGAGGGGYRRGGGNSGGGGG 66

  Fly    84 GGRREG------ERDFRGGEGGF--------RGGQGGSRGGQGGSR-------GGQGGFR----- 122
            ||...|      :||.|||.||:        ||..||  ||.||:|       ||.||:.
 Worm    67 GGYDRGYNDNRDDRDNRGGSGGYGRDRNYEDRGYNGG--GGGGGNRGYNNNRGGGGGGYNRQDRG 129

  Fly   123 -GGEGGFRGRLYENEDAKELPPIPSSCDKDEVGAFIDQLDLSKYTTSLALIRKLRDYLLTAFKAL 186
             ||...|....|.|.|.          ..|..|:.                   |.|
 Worm   130 DGGSSNFSRGGYNNRDE----------GSDNRGSG-------------------RSY-------- 157

  Fly   187 VNQAWASLEKLAQEKRAQKAHQIRETTDMMNRLMEDMGRLIREGEHEEANGIGMGFQSIDADCRA 251
                                          |....|.|          .:|....:.::||....
 Worm   158 ------------------------------NNDRRDNG----------GDGQNTRWNNLDAPPSR 182

  Fly   252 DLSQWRNLQQVVMPQSSEIRDGQTNRTSGTEGGRSGGLTDGDDLTEIQSAAYAVYHQVLDRGYQT 316
            ..|:|.|                       .|.|       |:..|          |.|..|..:
 Worm   183 GTSKWEN-----------------------RGAR-------DERIE----------QELFSGQLS 207

  Fly   317 GRRLYDDNQGALREDSIPTE----DREHPENNQVDGSTYGVTRFLH-WLSENFVTRHEIRAVRFG 376
            |.. :|      :.:.||.|    |...|.:...|.|       || |:.||..|
 Worm   208 GIN-FD------KYEEIPVEATGDDVPQPISLFSDLS-------LHEWIEENIKT---------- 248

  Fly   377 SPHMVFQSYDWPESPKQHISTVHQKGIFYSQPLIR-TRIIATVASEPNNSSSGQLSSMVNLARHQ 440
                  ..||.|        |..||   ||.|.:: .|.:.:.|...:..::..|..:||...
 Worm   249 ------AGYDRP--------TPVQK---YSIPALQGGRDLMSCAQTGSGKTAAFLVPLVNAIL-- 294

  Fly   441 RSQNQETPDGIYVSRYNATG-DEETPCSATGVPGRVVALRASSTPNEHRSDPGLSFIPNLTYEDG 504
                |:.||.::.|..::.| .::.|.:....|.|.::|:..   ||.|         ...|...
 Worm   295 ----QDGPDAVHRSVTSSGGRKKQYPSALVLSPTRELSLQIF---NESR---------KFAYRTP 343

  Fly   505 TIPSLAAGGAASTPLAPSLPAEHSLGLEMDSNTLVVP----ADADETRLVGHPGSTVVRSRLGGP 565
            ...:|..||..:.       .:....|.:..:.|:..    .|..:..|:|..|.
 Worm   344 ITSALLYGGRENY-------KDQIHKLRLGCHILIATPGRLIDVMDQGLIGMEGC---------- 391

  Fly   566 PASTPLLSFRPRLPVIDEEHHLRFTRVSRELQMSVAFPPEETTLSEQREWGSIFRPRDEMVNYAE 630
                       |..|:||                                      .|.|::...
 Worm   392 -----------RYLVLDE--------------------------------------ADRMLDMGF 407

  Fly   631 GPPPRQTQRARRRSRTRRRRNRIASAASP---QLTPERIVRREEAFQSSRHIAATFMSSLLQNAA 692
            .|..||.....|......|...:.||..|   ||..:..::....|.:...:.:| ..:::|
 Worm   408 EPQIRQIVECNRMPSKEERITAMFSATFPKEIQLLAQDFLKENYVFLAVGRVGST-SENIMQ--- 468

  Fly   693 GEVTTSSGLAVTRSVKEITTSVHITRNVLQEEVPPTTEATTTSLEVAQATGYSDSGACMQSAAFS 757
                           |.:.......|:.|.:.:..|.:::.|.:.|....|.||....:.    .
 Worm   469 ---------------KIVWVEEDEKRSYLMDLLDATGDSSLTLVFVETKRGASDLAYYLN----R 514

  Fly   758 QDLPVVAPLEISGNASSDQASFDQALALLPPINSTPIGQHPIAVFGPKTEIEIKPQKMDISNMMN 822
            |:..||.   |.|    |...|::...|    :....|..||.|     ...:..:.:||.|:.:
 Worm   515 QNYEVVT---IHG----DLKQFEREKHL----DLFRTGTAPILV-----ATAVAARGLDIPNVKH 563

  Fly   823 TSVPPMPMEVDEVPLEVSNT 842
            .....:|.:|||....:..|
 Worm   564 VINYDLPSDVDEYVHRIGRT 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
solo	NP_001027274.2	None
laf-1	NP_001254859.1	SrmB	233..619	CDD:440279	92/508 (18%)