DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SdicC and LOC798868

DIOPT Version :9

Sequence 1:	NP_001303578.1	Gene:	SdicC / 26067076	FlyBaseID:	FBgn0283434	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	XP_021326617.1	Gene:	LOC798868 / 798868	-ID:	-	Length:	608	Species:	Danio rerio

Alignment Length:	543	Identity:	267/543 - (49%)
Similarity:	366/543 - (67%)	Gaps:	63/543 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SGGKKQPLNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNGF 81
            :.|:::...|....:...:..|:|.:.|.|:|||.:.        |..::.|:||..
Zfish   101 AAGRRRSHRLGPSKITQVDFLPREVVSYCKETQTPNA--------AHHSEEDEEEDE-------- 149

  Fly    82 TSKLPPGYLTHGLPTVKDVAPAITPLEIKKETEVKKE--VNELSEEQKQMIILSENFQRFVVRAG 144
                         ...:..|...|.|:.::|::..||  ..||:||:||.::.||.|..|..|:.
Zfish   150 -------------EVTEPKAGPETDLQEEEESKDTKEGHPRELTEEEKQQVLHSEEFLIFFDRSI 201

  Fly   145 RVIERALSENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPKLV 209
            ||:||||:|:.:|:.||.|....::..|.:..:.|||:|:||||.|||:|.||.:|||..:|:|:
Zfish   202 RVMERALAEDSNIFFDYSGRDLEDKEGDMQGGSSLSLSRLFYDEHWSKHRVITCLDWSPQYPELL 266

  Fly   210 VGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLW 274
            |.||:|||::|:|||||.:|||.||||:|||.::||||.|:|..||.|:|||::|||||||||||
Zfish   267 VASYNNNEDAPHEPDGVALVWNMKFKKTTPEYIYHCQSPVVSVGFALFHPNLLVGGTYSGQIVLW 331

  Fly   275 DNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQ 339
            |||..:|||:||||||||||||||||:.:||||||:|:|::|:||::||||||||||||:::||.
Zfish   332 DNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNANNLITVSTDGRMCSWSLDMLSQPQESMELV 396

  Fly   340 QRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLS 404
            ..:||.:|:|.||||..::|:.::|||:|.||:|||||.::|:.|::|.|.||:||||.| :.:.
Zfish   397 YNKSKPVAVTGMAFPTGDVNNYIVGSEEGTVYTASRHGSKAGICEMFEGHQGPVTGISCH-SAVG 460

  Fly   405 P-DFGHLFLTSS----IKIWSLKLPISSCQFSVVSGINSNKPLYSFEDNSDYMMDVAWSPVHPAL 464
            | ||.|||:|||    :|:||.|               .||||||||||:||:.||.||||||:|
Zfish   461 PVDFSHLFVTSSFDWTVKLWSTK---------------QNKPLYSFEDNADYVYDVMWSPVHPSL 510

  Fly   465 FAAVDGSGRLDLWNLNQDTEVPTASIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLA 529
            ||||||.|||||||||.|||||:||:.|.||||||||.|...|..|.:||..|::::|||.| ||
Zfish   511 FAAVDGMGRLDLWNLNNDTEVPSASVTVEGAPALNRVRWASGGREVAVGDSEGRVWIYDVGE-LA 574

  Fly   530 QPSRD----------EIKMNQSD 542
            .|..|          ||:.|:.|
Zfish   575 VPHADDWTRFGRTLMEIRANRGD 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SdicC	NP_001303578.1	Dynein_IC2	23..51	CDD:288403	7/27 (26%)
		NtpH	108..>178	CDD:225368	26/71 (37%)
		WD40	196..523	CDD:295369	201/331 (61%)
		WD40 repeat	196..245	CDD:293791	29/48 (60%)
		WD40	<224..534	CDD:225201	192/314 (61%)
		WD40 repeat	251..289	CDD:293791	27/37 (73%)
		WD40 repeat	298..337	CDD:293791	26/38 (68%)
		WD40 repeat	349..386	CDD:293791	19/36 (53%)
		WD40 repeat	393..446	CDD:293791	24/57 (42%)
		WD40 repeat	452..491	CDD:293791	31/38 (82%)
		WD40 repeat	498..522	CDD:293791	10/23 (43%)
LOC798868	XP_021326617.1	Dynein_IC2	109..135	CDD:314442	7/25 (28%)
		WD40	246..569	CDD:330360	205/338 (61%)
		WD40 repeat	253..302	CDD:293791	29/48 (60%)
		WD40 repeat	308..346	CDD:293791	27/37 (73%)
		WD40 repeat	355..398	CDD:293791	28/42 (67%)
		WD40 repeat	406..452	CDD:293791	23/45 (51%)
		WD40 repeat	459..492	CDD:293791	19/47 (40%)
		WD40 repeat	498..539	CDD:293791	31/40 (78%)
		WD40 repeat	544..568	CDD:293791	10/23 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1453532at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010