Protein Alignment SdicB and Dnai4

DIOPT Version :10

• Sequence 1: NP_001303577.1
• Gene: SdicB / 26067075
• FlyBaseID: FBgn0283433
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_036020022.1
• Gene: Dnai4 / 242584
• MGIID: 2385328
• Length: 812
• Species: Mus musculus
• Alignment Length: 611
• Identity: 134/611 - (21%)
• Similarity: 233/611 - (38%)
• Gaps: 155/611 - (25%)

  Fly     8 FLRSTYSTLSGGKK------QPLNLSVYNVQAT--------NIPPKETLVYTKQTQTTSTGGGNG 58
            ::.....|.:|..|      :.:.|....|.||        |||  |||:..|::..:|    .|
Mouse   246 YVERMMQTFNGAPKNKEVQCEKIILEEKGVVATTWDLYDSYNIP--ETLLAAKRSGYSS----KG 304

  Fly    59 DVLAFDAQ---GDDEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAPAITPLEIKKETEVKKEVN 120
            .:.|.|..   .|.|.|||.::.|...:|                                  |.
Mouse   305 SLPAKDRDPKIQDSESSSLMDIENVILAK----------------------------------VQ 335

  Fly   121 ELSEEQKQMIILSENFQRFVVRAGRVIERALSENV-----------DIYTDY------------- 161
            |..|:..:.|:.|:...:.:.    .:||.|.|||           .:|.::
Mouse   336 EDEEDNSEAILKSDKLHQDLF----YMERVLMENVFQPKLAAYRQLPVYKEHEPEEPEETLQVEN 396

  Fly   162 IGGGDSEEANDERSHARLSLNRVFYDER----------WS------KNRCITSMDWSTHFPELVV 210
            :...:.|...::.....:.|......|:          ||      |...::|:.|:...|:|:.
Mouse   397 LKVAEDEPKKEDEEEVEMELELEIATEQSTIPANLERLWSFSCDLTKGLNVSSLSWNKANPDLLA 461

  Fly   211 GSYHN---NEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIV 272
            ..|.|   .|:.    .|:...|:.| ....||.::.....|.|..|:..:|||:..|.::|.:.
Mouse   462 VGYGNFGFREQK----KGMACCWSIK-NPMWPERIYQSSYGVTSVDFSNSSPNLLAVGYHNGTVA 521

  Fly   273 LWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMV-------GTQNAHNVISISSDGKLCSWSLDMLS 330
            :::.:.....|:..:..|...|..||:.:|.:       |......::|||:||::..|.:....
Mouse   522 IYNVQSSHNIPVLDSSESPQKHLGPVWQVQWIEQDRGTTGDDKREILVSISADGRISKWIIRKGL 586

  Fly   331 QPQDTLELQ-----------QRQSKAIAITS-------MAFPANEINSLVMGSEDGYVYSASRHG 377
            ...|.:.|:           :::.|..|:.|       .||...:.|..:.|:|:|.::..|
Mouse   587 DCHDLMRLKRTTATGGKKGGEKEKKGEALISRQAPGMCFAFHPKDTNIYLAGTEEGLIHKCS--- 648

  Fly   378 LRSGVN----EVYERHLGPITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNS 438
              ...|    |.|..|.||:..::  :|...||   :||:.|.||.:.:|.....||..||...:
Mouse   649 --CSYNEQYLETYRGHKGPVYKVT--WNPFCPD---VFLSCSADWGVMIWHQDTVKPFLSFYPTT 706

  Fly   439 DYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPIASIVVAGAPAL--NRVSWTPSGLHVCI 501
            ..|.||:|||....:|||.: ..|:::|:|...|..|:  ||....|.:  ..|.:......:.:
Mouse   707 YVVYDVSWSPKSAYIFAAAN-ENRVEIWDLQISTLDPL--IVNVANPGIKFTTVLFAKETDCLLV 768

  Fly   502 GDEAGKLYVYDVAE--NLAQPSRDEI 525
            ||..|::.||::..  ..:..|||.|
Mouse   769 GDSDGQVAVYELRNMPTASDTSRDWI 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdicB	NP_001303577.1	Dynein_IC2	21..51	CDD:463291	12/43 (28%)
		WD40	196..512	CDD:475233	86/349 (25%)
		WD40 repeat	196..245	CDD:293791	12/51 (24%)
		WD40 repeat	251..289	CDD:293791	8/37 (22%)
		WD40 repeat	298..337	CDD:293791	10/45 (22%)
		WD40 repeat	349..435	CDD:293791	26/96 (27%)
		WD40 repeat	441..479	CDD:293791	14/37 (38%)
		WD40 repeat	487..513	CDD:293791	6/27 (22%)
Dnai4	XP_036020022.1	WD40 repeat	448..493	CDD:293791	12/49 (24%)
		WD40	<480..782	CDD:441893	79/315 (25%)
		WD40 repeat	498..542	CDD:293791	10/43 (23%)
		WD40 repeat	548..617	CDD:293791	12/68 (18%)
		WD40 repeat	622..660	CDD:293791	9/42 (21%)
		WD40 repeat	667..702	CDD:293791	11/39 (28%)
		WD40 repeat	709..741	CDD:293791	13/32 (41%)
		WD40 repeat	751..780	CDD:293791	6/28 (21%)