Protein Alignment SdicB and dyci-1

DIOPT Version :10

• Sequence 1: NP_001303577.1
• Gene: SdicB / 26067075
• FlyBaseID: FBgn0283433
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001370459.1
• Gene: dyci-1 / 177440
• WormBaseID: WBGene00015927
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 209/540 - (38%)
• Similarity: 317/540 - (58%)
• Gaps: 39/540 - (7%)

  Fly    24 LNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNG-FTSKLPP 87
            ::|...:||......|::.:|:|.|||.......|:......:.|.::..:..:.:| |..:...
 Worm   105 VDLEFSSVQTACTDNKDSAIYSKGTQTDDERISVGEFSLGSQEFDYDDDMIMPMDHGQFRGRAHS 169

  Fly    88 GYLTHGLPTVKDVAPAITPLE------IKKETEVKKE-----VNELSEEQKQMIILSENFQRFVV 141
            ......||..:::|..:...:      .::|||.||.     |..||:|:|..:.|...|.....
 Worm   170 HDQDSPLPYNEEIAKLLGQTKQGDKGLTRQETEEKKTQTVQIVPPLSDEEKYRLTLDPEFLDSFN 234

  Fly   142 RAGRVIERALSENVDIYTDYIGGGDSEE---ANDERSHARLSLNRVFYDERWSKNRCITSMDWST 203
            |:.:||.|||:|.:||..:|.  .|..|   |:|:..|    |.:|:.||.|:..|.:|.|.:|.
 Worm   235 RSCKVISRALNEEIDICINYT--KDPYEKAIASDDLLH----LAQVYQDETWTAKRLVTGMAFSE 293

  Fly   204 HFPELVVGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYS 268
            |:|:|:..|| ...:.||||.||::|||||.|:.|.|.:.:|||.:.|..||:|:.:|:|.|..|
 Worm   294 HYPDLLAVSY-GPCDIPNEPPGVIVVWNTKSKRMTAEFIVYCQSEIQSVAFARFHAHLLLAGCES 357

  Fly   269 GQIVLWDNRV-QKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQP 332
            |||.:||||: .::.||.|:||:..|||:.|.||.:|||:||||.:|:|.||::|||::|.|:||
 Worm   358 GQICVWDNRLTSRKLPINRSPLTTQAHTYTVSCLAVVGTKNAHNFVSLSRDGRICSWNVDNLTQP 422

  Fly   333 QDTLELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGV---NEVYERHLGPIT 394
            .|..||..::.||.:.|.|:||..|:.:.|:|::.|.:.:|||:|....|   :..|:.|.|.:|
 Worm   423 VDGKELMTKEGKAASATRMSFPIGEMQTFVVGTDTGEILAASRNGADPAVIKTDVCYKGHSGTLT 487

  Fly   395 GISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDG 459
            ||..|......||.|||::||.|||:||||.||....:|||.:.|.|:||||||||||:||::|.
 Worm   488 GIEFHRASGVVDFSHLFISSSHDWTVKLWSTKDANLKFSFESHPDLVLDVAWSPVHPAVFASIDA 552

  Fly   460 SGRLDLWNLNQDTEVPIASIVVAGAPA----LNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQP 520
            .|.:.:||||:|.|.|:|.: .|||..    :||:.|:|.|.||.:||:.|::::|||.|:|...
 Worm   553 DGNIFVWNLNEDVEGPVARL-RAGAEGESVYMNRLIWSPDGKHVFVGDDEGRVHMYDVRESLYVL 616

  Fly   521 SRDE--------IKMNQSDE 532
            ..:|        ..|.||:|
 Worm   617 KSEEWNRFARVLSDMKQSNE 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdicB	NP_001303577.1	Dynein_IC2	21..51	CDD:463291	8/26 (31%)
		WD40	196..512	CDD:475233	150/323 (46%)
		WD40 repeat	196..245	CDD:293791	22/48 (46%)
		WD40 repeat	251..289	CDD:293791	18/38 (47%)
		WD40 repeat	298..337	CDD:293791	22/38 (58%)
		WD40 repeat	349..435	CDD:293791	37/88 (42%)
		WD40 repeat	441..479	CDD:293791	23/37 (62%)
		WD40 repeat	487..513	CDD:293791	11/25 (44%)
dyci-1	NP_001370459.1	WD40	<257..610	CDD:441893	163/358 (46%)
		WD40 repeat	286..333	CDD:293791	22/47 (47%)
		WD40 repeat	339..383	CDD:293791	20/43 (47%)
		WD40 repeat	388..457	CDD:293791	33/68 (49%)
		WD40 repeat	487..528	CDD:293791	21/40 (53%)
		WD40 repeat	534..573	CDD:293791	23/39 (59%)
		WD40 repeat	581..609	CDD:293791	11/27 (41%)