Protein Alignment SdicB and Dync1i2

DIOPT Version :10

• Sequence 1: NP_001303577.1
• Gene: SdicB / 26067075
• FlyBaseID: FBgn0283433
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001185801.1
• Gene: Dync1i2 / 13427
• MGIID: 107750
• Length: 655
• Species: Mus musculus
• Alignment Length: 527
• Identity: 285/527 - (54%)
• Similarity: 369/527 - (70%)
• Gaps: 52/527 - (9%)

  Fly    23 PLNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNGFTSKLPP 87
            |:.|.:..:...:.||:|.:.|||:|||..|.         ..:.|:||..
Mouse   152 PIKLGMAKITQVDFPPREIVTYTKETQTPVTA---------QPKEDEEEED-------------- 193

  Fly    88 GYLTHGLPTVKDVAPAITPLEIKKETEVKKE--------VNELSEEQKQMIILSENFQRFVVRAG 144
                       |||....|:|.::|..:||:        .:||:||:||.|:.||.|..|...:.
Mouse   194 -----------DVATPKPPVEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHST 247

  Fly   145 RVIERALSENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELV 209
            |::||||||.::|:.||.|....::..:.::.|:|||||.|:||||||:|.::.:|||:.:|||:
Mouse   248 RIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELL 312

  Fly   210 VGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLW 274
            |.||:||||:|:|||||.:|||.|:||:|||.||||||||||..||||:|||::|||||||||||
Mouse   313 VASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLW 377

  Fly   275 DNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQ 339
            |||..||||:||||||||||||||||:.:||||||||:||||:|||:|||||||||.|||::||.
Mouse   378 DNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELV 442

  Fly   340 QRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLS 404
            .:||||:|:|||:||..::|:.|:|||:|.||:|.|||.::|::|::|.|.||||||..|....:
Mouse   443 HKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGA 507

  Fly   405 PDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLN 469
            .||.|||:|||.|||:|||:.|:.|||||||||||||.||.|||.||||||.|||.|||||||||
Mouse   508 VDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLN 572

  Fly   470 QDTEVPIASIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRD----------E 524
            .|||||.|||.|.|.||||||.||.||..:.:||..|::.:|||.|.:|.|..|          |
Mouse   573 NDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAE 637

  Fly   525 IKMNQSD 531
            |..|::|
Mouse   638 INANRAD 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdicB	NP_001303577.1	Dynein_IC2	21..51	CDD:463291	10/27 (37%)
		WD40	196..512	CDD:475233	215/315 (68%)
		WD40 repeat	196..245	CDD:293791	30/48 (63%)
		WD40 repeat	251..289	CDD:293791	29/37 (78%)
		WD40 repeat	298..337	CDD:293791	30/38 (79%)
		WD40 repeat	349..435	CDD:293791	48/85 (56%)
		WD40 repeat	441..479	CDD:293791	30/37 (81%)
		WD40 repeat	487..513	CDD:293791	12/25 (48%)
Dync1i2	NP_001185801.1	Dynein_IC2	150..180	CDD:463291	10/27 (37%)
		WD40 repeat	299..348	CDD:293791	30/48 (63%)
		WD40	<327..430	CDD:441893	82/102 (80%)
		WD40 repeat	356..394	CDD:293791	30/37 (81%)
		WD40	397..>622	CDD:475233	147/224 (66%)
		WD40 repeat	402..443	CDD:293791	31/40 (78%)
		WD40 repeat	451..498	CDD:293791	24/46 (52%)
		WD40 repeat	506..538	CDD:293791	20/31 (65%)
		WD40 repeat	544..582	CDD:293791	30/37 (81%)
		WD40 repeat	590..616	CDD:293791	12/25 (48%)