Protein Alignment SdicA and LOC4576277

DIOPT Version :10

• Sequence 1: NP_001303576.1
• Gene: SdicA / 26067074
• FlyBaseID: FBgn0283432
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_001237748.2
• Gene: LOC4576277 / 4576277
• VectorBaseID: AGAMI1_000491
• Length: 693
• Species: Anopheles gambiae
• Alignment Length: 558
• Identity: 122/558 - (21%)
• Similarity: 221/558 - (39%)
• Gaps: 126/558 - (22%)

  Fly    32 QATNIPPKETLVYTK--QTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNGFTSKLPPGYLTHGL 94
            |..::|.|...|.|:  ..|..::...|.|:  :|...|.|.         .|.::
Mosquito   179 QTRDLPCKSRSVNTECIHRQDVASFVSNYDM--YDTYNDLER---------HTKEI--------- 223

  Fly    95 PTVKDVAPAITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAGRVIERALSENV---- 155
                :||.:.:.|||  .|..::.:.::.|...:    :.||.    .:..:::|.|:.||
Mosquito   224 ----NVADSASKLEI--TTYSREGMEDIDERLNR----NANFH----LSSMILQRLLAGNVYREQ 274

  Fly   156 -----DIYTDYIGGGDSEEANDERSHARLSLNRVFYDERW------SKNRCITSMDWSTHFPELV 209
                 ::|.      ......|.|...||       |..|      :..:.:.|..|.....::|
Mosquito   275 QIRFRNMYP------PDPCREDIRYLYRL-------DVLWTYRTVETLGKPVASASWCPANGDIV 326

  Fly   210 VGSY--HNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIV 272
            ..:|  :.:..|.:...|.|.|||.| ....||..:.....|....|::..|.|:..|.|.|::
Mosquito   327 ALAYGIYGHTGSDDRGCGFVYVWNIK-NPVNPERRYRFDCPVTCVAFSRRTPQLLAVGLYDGRV- 389

  Fly   273 LWDNRVQKRTPIQRTPLSAAAHT-----HPVYCLQMVGTQN--AHNVISISSDGKLCSWSLD--- 327
                :|:..|...:|||:.:...     .|::.|:.|...|  ...||::|.:|.:..::|.
Mosquito   390 ----QVRDITDTTQTPLAVSNRDRFPVYQPIWDLKWVEFDNEGKDEVIAVSQNGWVMKYTLTIGQ 450

  Fly   328 -MLSQPQDTLELQQRQSKAIAITSMAFPAN----------------------EINSLVMGSEDGY 369
             :|..|...|:..:...:....|..:.||:                      :.:...:|:::|.
Mosquito   451 YLLPYPLLRLDRVEGTPEGQTSTGTSAPADQQPVRVQSDLHPQALCVTIHPVQKDKYYIGTDEGA 515

  Fly   370 VYSASRHGLRSGVNEVYERHLGPI----TGI-STHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTK 429
            |:..|       :|:.:: |||.:    .|| ...|:..||   .:|||.|.||:|::|..:..:
Mosquito   516 VHWCS-------INDPFQ-HLGVLQMHSRGIFCLEYSPWSP---RIFLTCSGDWSIRIWIEELPE 569

  Fly   430 PLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPIASIVVAGA--PALNRVSW 492
            |:.:.......:....|||.:..:.|:|..|| :.||:|.:.:..| ||....|:  .||..|.:
Mosquito   570 PIVTLCTGFAPIQAAYWSPTNSTVIASVTRSG-VQLWDLKRRSSKP-ASETTLGSLTTALTVVRF 632

  Fly   493 TPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEIKMNQS 530
            |..|..:.:||..||.:|. ..|::..|...:.:..||
Mosquito   633 TNCGRCLLVGDAEGKAHVC-ALEDMPFPPHFQYRELQS 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdicA	NP_001303576.1	Dynein_IC2	21..51	CDD:463291	6/20 (30%)
		WD40	196..512	CDD:475233	86/357 (24%)
		WD40 repeat	196..245	CDD:293791	13/50 (26%)
		WD40 repeat	251..289	CDD:293791	9/37 (24%)
		WD40 repeat	298..337	CDD:293791	10/44 (23%)
		WD40 repeat	349..435	CDD:293791	25/112 (22%)
		WD40 repeat	441..479	CDD:293791	12/37 (32%)
		WD40 repeat	487..513	CDD:293791	9/25 (36%)
LOC4576277	XP_001237748.2	WD40	<294..650	CDD:441893	89/381 (23%)
		WD40 repeat	368..406	CDD:293791	11/42 (26%)
		WD40 repeat	416..489	CDD:293791	14/72 (19%)
		WD40 repeat	497..533	CDD:293791	8/43 (19%)
		WD40 repeat	538..574	CDD:293791	13/38 (34%)
		WD40 repeat	581..621	CDD:293791	13/41 (32%)
		WD40 repeat	627..664	CDD:293791	11/37 (30%)