Protein Alignment SdicA and dync1i1

DIOPT Version :10

• Sequence 1: NP_001303576.1
• Gene: SdicA / 26067074
• FlyBaseID: FBgn0283432
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001106382.1
• Gene: dync1i1 / 100127187
• XenbaseID: XB-GENE-490874
• Length: 627
• Species: Xenopus tropicalis
• Alignment Length: 504
• Identity: 271/504 - (53%)
• Similarity: 355/504 - (70%)
• Gaps: 35/504 - (6%)

  Fly    24 LNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLAFDAQGDDEESSLQNLGNGFTSKLPPG 88
            :.|.|..|...:..|:|.:.|:|:|||        .|.....:.::|:..:.:|.....|:
 Frog   129 IKLGVSKVTQVDFLPREVVSYSKETQT--------PVTTHQTEEEEEDEEMVDLKTEHDSE---- 181

  Fly    89 YLTHGLPTVKDVAPAITPLEIKKETEVKKEV--NELSEEQKQMIILSENFQRFVVRAGRVIERAL 151
                              .|.::|.:..:||  .||:||:||.:..||.|..|..|..|||||||
 Frog   182 ------------------FENQEEKQDSREVPPRELTEEEKQQVTHSEEFLIFFDRTIRVIERAL 228

  Fly   152 SENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNN 216
            :|:.:|:.||.|....::..|.::.|.||.||.||||.|||:|.:|.:|||..:|||:|.||:||
 Frog   229 AEDSNIFFDYSGRDLEDKEGDIQAGANLSFNRQFYDEHWSKHRVVTCLDWSLQYPELMVASYNNN 293

  Fly   217 EESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKR 281
            |::|:|||||.:|||.||:|:|||.:|||||:|||.|||:|:|||::||||||||||||||..:|
 Frog   294 EDAPHEPDGVALVWNMKFRKTTPEYIFHCQSSVMSVCFARFHPNLVIGGTYSGQIVLWDNRSHRR 358

  Fly   282 TPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAI 346
            ||:|||||||||||||:||:.:||||||||:|::|:|||||||||||||.||:::||...:||.:
 Frog   359 TPVQRTPLSAAAHTHPIYCVNVVGTQNAHNLITVSTDGKLCSWSLDMLSAPQESMELVYNKSKPV 423

  Fly   347 AITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSP-DFGHL 410
            |:|.||||..::|:.|:|||:|.||:|.|||.::|::||:|.|.||:|||:.| |.:.| ||.||
 Frog   424 AVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGISEVFEGHQGPVTGINCH-NAVGPIDFSHL 487

  Fly   411 FLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVP 475
            |||||.|||:|||:.|..|||||||||:|||.||.||||||||||.|||.|||||||||.|||||
 Frog   488 FLTSSFDWTVKLWTTKHNKPLYSFEDNADYVCDVTWSPVHPALFACVDGMGRLDLWNLNNDTEVP 552

  Fly   476 IASIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDE 524
            .||..|.||.|||||.|..||..|.:||..|::::|||.| .:.|..||
 Frog   553 TASTAVEGASALNRVRWAQSGKEVAVGDSEGRVWIYDVGE-FSIPHNDE 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SdicA	NP_001303576.1	Dynein_IC2	21..51	CDD:463291	9/26 (35%)
		WD40	196..512	CDD:475233	209/316 (66%)
		WD40 repeat	196..245	CDD:293791	29/48 (60%)
		WD40 repeat	251..289	CDD:293791	28/37 (76%)
		WD40 repeat	298..337	CDD:293791	27/38 (71%)
		WD40 repeat	349..435	CDD:293791	51/86 (59%)
		WD40 repeat	441..479	CDD:293791	31/37 (84%)
		WD40 repeat	487..513	CDD:293791	12/25 (48%)
dync1i1	NP_001106382.1	Dynein_IC2	126..156	CDD:463291	10/34 (29%)
		WD40 repeat	274..319	CDD:293791	28/44 (64%)
		WD40	<301..590	CDD:441893	194/289 (67%)
		WD40 repeat	329..368	CDD:293791	29/38 (76%)
		WD40 repeat	376..419	CDD:293791	29/42 (69%)
		WD40 repeat	425..464	CDD:293791	20/38 (53%)
		WD40 repeat	480..512	CDD:293791	22/31 (71%)
		WD40 repeat	518..556	CDD:293791	31/37 (84%)
		WD40 repeat	564..590	CDD:293791	12/25 (48%)