Protein Alignment Fatp1 and FAA2

DIOPT Version :10

• Sequence 1: NP_001162940.3
• Gene: Fatp1 / 26067068
• FlyBaseID: FBgn0267828
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_010931.3
• Gene: FAA2 / 856734
• SGDID: S000000817
• Length: 744
• Species: Saccharomyces cerevisiae
• Alignment Length: 695
• Identity: 148/695 - (21%)
• Similarity: 238/695 - (34%)
• Gaps: 219/695 - (31%)

  Fly   177 TVADVFERNVQAHPDKVAVVSE-----TQRW--TFR-----QVNEHANKV-------ANVLQAQG 222
            |..|.|..:.:..|.:..:.|.     |..|  |||     .|::..:.:       .|..:.:.
Yeast    94 TAYDHFMFSARRWPQRDCLGSRPIDKATGTWEETFRFESYSTVSKRCHNIGSGILSLVNTKRKRP 158

  Fly   223 YKKGD-VVALLLENRAEYVATWLGLSKIGVITPLINTNL---RGPSLL-HSITVAHCSALIYGED 282
            .:..| |||:|..|..|::.|.|......    |.||.|   .||:.. :.:.:.....||:.:.
Yeast   159 LEANDFVVAILSHNNPEWILTDLACQAYS----LTNTALYETLGPNTSEYILNLTEAPILIFAKS 219

  Fly   283 FLEAVTDVAKDLPANLTLF---QFNNENNNSETEKNIP-QAKNLNALLTTASYEKPNKTQVNHHD 343
            .:..|..:..|:....||.   :..::......|..:| :..:||..:|..|.|:..  ||...:
Yeast   220 NMYHVLKMVPDMKFVNTLVCMDELTHDELRMLNESLLPVKCNSLNEKITFFSLEQVE--QVGCFN 282

  Fly   344 KLVYI-----------YTSGTTGLPKAAVISHSRYLFIAAGIHYTMGFQEEDIFYTP-------- 389
            |:..|           :|||||||||...:||..   ||:||.:..     ..|..|
Yeast   283 KIPAIPPTPDSLYTISFTSGTTGLPKGVEMSHRN---IASGIAFAF-----STFRIPPDKRNQQL 339

  Fly   390 -----LPLYHTAGGIMCMGQSVLFGSTVSIRKKFSASNYFADCAKYNATIGQYIGEMAR------ 443
                 |||.|            :|...|               ..|:..||..||.:.:
Yeast   340 YDMCFLPLAH------------IFERMV---------------IAYDLAIGFGIGFLHKPDPTVL 377

  Fly   444 ---------YILATKPSEYDQKHRVRLVFGNGLRPQIWPQFVQRFNIA------KVGEFYGATEG 493
                     |.:|..|       |:...|..|::..:....||| |:|      |...|......
Yeast   378 VEDLKILKPYAVALVP-------RILTRFEAGIKNALDKSTVQR-NVANTILDSKSARFTARGGP 434

  Fly   494 NANIMNH--------DNTVGAIGFV--SRILPKIYPIS-----IIRADPDTGEPIRDRNGL---- 539
            :.:|||.        |....::|..  |.|:....|||     .:|:..|.|  ||...||
Yeast   435 DKSIMNFLVYHRVLIDKIRDSLGLSNNSFIITGSAPISKDTLLFLRSALDIG--IRQGYGLTETF 497

  Fly   540 ------------------------CQLCAPNEPGVFIGKIVKG---------------NPSREFL 565
                                    |:|.:..|.|....|.:||               ||:.
Yeast   498 AGVCLSEPFEKDVGSCGAIGISAECRLKSVPEMGYHADKDLKGELQIRGPQVFERYFKNPNE--- 559

  Fly   566 GYVDEKASAKKIVKD-VFKHGDMAFISGDLLVADEKGYLYFKDRTGDTFRW-KGENVSTSEVE-- 626
                   ::|.:.:| .|..||:|||.|       ||.:...||..:.|:. .||.::..::|
Yeast   560 -------TSKAVDQDGWFSTGDVAFIDG-------KGRISVIDRVKNFFKLAHGEYIAPEKIENI 610

  Fly   627 -----AQVSNVAGYKD---TVVYGVTIPHTEGRAGMAAIYDPE-RELDLDVFAASLAKVLPAYAR 682
                 ..::.:..:.|   |.:.|:.....:....:.|...|| :....:|...:|.:  ....|
Yeast   611 YLSSCPYITQIFVFGDPLKTFLVGIVGVDVDAAQPILAAKHPEVKTWTKEVLVENLNR--NKKLR 673

  Fly   683 PQIIRLLTKV--DLTGTFKLRKVDLQKEGYDPNAIKDALYYQTSK 725
            .:.:..:.|.  .|.|..||..:   |.|.:|..::|.:...|.|
Yeast   674 KEFLNKINKCTDGLQGFEKLHNI---KVGLEPLTLEDDVVTPTFK 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp1	NP_001162940.3	hsFATP4_like	199..712	CDD:341262	139/653 (21%)
FAA2	NP_010931.3	LC-FACS_euk	126..734	CDD:341250	141/663 (21%)