DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp1 and CG11391

DIOPT Version :9

Sequence 1:	NP_001162940.3	Gene:	Fatp1 / 26067068	FlyBaseID:	FBgn0267828	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_650830.1	Gene:	CG11391 / 42353	FlyBaseID:	FBgn0038732	Length:	542	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	128/539 - (23%)
Similarity:	223/539 - (41%)	Gaps:	97/539 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 ATASRDLTALWAYIKLLRYTKRHERLNYTVADVFERNVQAHPDKVAVVSETQ--RWTFRQVNEHA 211
            ||:...:..:|:...  |::..:|.|  ||..:..|.:|..|.::..:|.|.  |.|..|:.::|
  Fly     9 ATSYDPVQKVWSGCS--RHSLYNEEL--TVGQIIFRQLQRQPQRIFQISHTDNTRLTRFQMLQNA 69

  Fly   212 NKVANVLQAQGYKK-GDVVALLLENRAEYVATWLGLSKIGVI---TPL--INTNLRGPSL--LHS 268
            .|:...|:.||:|| .|:|.|:..|     :|.:|....|.:   ||.  :|.||...::  |:.
  Fly    70 AKIGCYLRDQGFKKETDLVGLMARN-----STHVGALAYGCLFNGTPFHAVNPNLEHNTISSLYK 129

  Fly   269 IT---VAHCSALIYGEDFLEAVTDVAKDLPANLTLFQFNNENNNSETEKNIPQAKNLNALLTTA- 329
            ||   :..|....|     |.:.|:...|.|  .:...|.:         :|...::..:|...
  Fly   130 ITRPRILCCDTADY-----EKIKDIGASLGA--LIITVNGK---------LPGVISVADILQNPL 178

  Fly   330 --SYEKPNKTQVNHHDKLVYIYTSGTTGLPKAAVISHSRYLFIAAGIHYTMGFQEEDIFYTPLPL 392
              .|| |.:.|......:..:.:|||||.|||..:|:||.||   .:|..:|  .:|:.|.|..|
  Fly   179 PDDYE-PAQFQRGVDRTMAILCSSGTTGTPKAVTLSNSRKLF---EMHSYLG--SDDVQYAPSTL 237

  Fly   393 YHTAGGIMCMGQSVLFGSTVSIRKKFSASNYFADCAKYNATIGQYIGEMARYILATKPSEYDQKH 457
             ....|::.:..:.:||:...|..:..::.:|.|..:.:......:......:||..|....||.
  Fly   238 -DWLTGLITLVTAAVFGTVRLISSEMFSTAHFLDICEQHEVSWTIMANSHVAMLANCPKTSAQKL 301

  Fly   458 R--VRLVFGNG------LRPQIWPQFVQRFNIAKVGEFYGATEGNANIMNHDNTVGAIGFVSRIL 514
            |  ..|:|..|      |:..  ..|:....|.:  ..||.||....:..:.:|......|.|::
  Fly   302 RSLKHLLFAGGHCLVATLKKM--QSFLHGSGILR--NAYGLTEVGTLVSYNYDTQSKPTSVGRLM 362

  Fly   515 PKIYPISIIRADPDTGEPIRDRNGLCQ-LCAPNEPGVFIGKIVKGNP-----SREFLGYVDEKAS 573
            ..| .:.|:    |:...::...||.: ||...:|  :.|.:  |||     .|:..|:
  Fly   363 ANI-RVKIV----DSSGQLQGPKGLGEILCHNGQP--WSGYV--GNPLATAEMRDSAGW------ 412

  Fly   574 AKKIVKDVFKHGDMAFISGDLLVADEKGYLYFKDRTGDTFRWKGENVSTSEVEAQVSNVAGYKDT 638
                           :.:||:...||..||:..:|..|..::.|......|||..::.:....:.
  Fly   413 ---------------YHTGDVGYFDEDHYLHIVERKKDMLKYLGMMYYPHEVEEVIAQMPDVAEV 462

  Fly   639 VVYGVTIPHTEGRAGMAAI 657
            .|:|: ...|||.|..|::
  Fly   463 CVFGI-FRETEGDAAAASV 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp1	NP_001162940.3	PRK08279	153..746	CDD:236217	126/535 (24%)
Fatp1	NP_001162940.3	hsFATP4_like	199..712	CDD:213305	116/489 (24%)
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	125/522 (24%)
CG11391	NP_650830.1	AFD_class_I	51..527	CDD:302604	117/493 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452167
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840