DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp1 and LOC316124

DIOPT Version :9

Sequence 1:	NP_001162940.3	Gene:	Fatp1 / 26067068	FlyBaseID:	FBgn0267828	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_006244385.1	Gene:	LOC316124 / 316124	RGDID:	1595856	Length:	705	Species:	Rattus norvegicus

Alignment Length:	556	Identity:	109/556 - (19%)
Similarity:	193/556 - (34%)	Gaps:	164/556 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 TVADVFERNVQAHPDKVAVVSETQR-W---TFRQVNEHANKVANVLQAQGYKKGDVVALLLENRA 237
            ||.|:.......:...:|:.|:.:: |   |:.:..|...:.|......|.::...|.::..|.:
  Rat    74 TVPDLIMSAATKYSHYLAIGSKYKKSWQVLTYIEYYEACRRAAKAFLKVGLERFHGVGIMGINSS 138

  Fly   238 EYVATWLG-LSKIGVITPLINTNLRGPSLLHSITVAHCSAL----IYGEDFLEAVTDVAKDLPAN 297
            |:|...:| :...|:...::::|  .|....  .:|..|.:    :..:..|:.|..:...|...
  Rat   139 EWVIASIGAIMAGGISVGILSSN--SPKACQ--IIAETSEMDIFVVDNDRQLQKVNQIQGYLKHL 199

  Fly   298 LTLFQFNNENNNSETEKNIPQAKNLNALLTTASYE---------KPNKTQVNHHDKLVYIYTSGT 353
            ..:.|:..:  ..|.:.|:...|....|....|.|         |||:.       ...:|..||
  Rat   200 KAIIQYRED--IQEVQPNLYSWKGFLDLADGISDEKLDQIIDAQKPNQC-------CALVYNQGT 255

  Fly   354 TGLPKAAVISHSRYLFIAAGIHYTMGFQ----EEDIFYTPLPLYHTAGGIMCMGQSVLFGSTVSI 414
            ||.|||.::||....:..|....::|::    .::|..:.|||......|:.:..::....||
  Rat   256 TGNPKAIMLSHDNITWTTAATVQSLGYKCPPHGQEILVSYLPLCFAGIQILDVWVAISVAGTV-- 318

  Fly   415 RKKFSASNYFADCAKYNATIGQYIG-----------EMARYILATK----PSEYDQ-------KH 457
                    ||.....     |::.|           |:.|.:..|.    |..:|:       ||
  Rat   319 --------YFPSLES-----GKWSGLPRVSGTGFLMELLREVQPTTFCGIPWVWDRMLDSLKTKH 370

  Fly   458 ---------------------RVRLVFGNGLRPQIWPQFVQRFNIAKVGEFYGATEGNANIMNHD 501
                                 ..|.:.| |:...:.....:|.......:|.|        :||.
  Rat   371 LDSTAFRRKIDRWAMRMGLSTNKRQMMG-GIHQPLCFGLAKRLTFKPAKKFLG--------LNHC 426

  Fly   502 NTVGAIG----------FVSRILP--KIYPIS---------------II---RADPDTGEPIRDR 536
            .....:|          |:|..:|  ::|.:|               |:   :|.|.|...:...
  Rat   427 EQFLNVGMGLPRSTLDFFLSMNIPILELYGLSECTGLHTLSSLQAYRILSSGKALPKTHTKVEKE 491

  Fly   537 N--GLCQLCAPNEPGVFIGKIVKGNPSREFLGYVDEKASAKKIVKDVFKHG-----DMAFISGDL 594
            |  |:..||       ..|:.|       |:||:.:|.|.::.|.:   ||     |:.|:..|
  Rat   492 NQDGVGNLC-------IWGRHV-------FMGYLRDKHSTERKVDN---HGWLHTNDLGFLDFD- 538

  Fly   595 LVADEKGYLYFKDRTGDTFRW-KGENVSTSEVEAQV 629
                  .|||....|.|..|. .||.|:...:|.:|
  Rat   539 ------KYLYVTGNTNDLIRLNSGEMVNPIPIEERV 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp1	NP_001162940.3	PRK08279	153..746	CDD:236217	109/556 (20%)
Fatp1	NP_001162940.3	hsFATP4_like	199..712	CDD:213305	104/534 (19%)
LOC316124	XP_006244385.1	FAA1	74..701	CDD:223953	109/556 (20%)
LOC316124	XP_006244385.1	ACSBG_like	95..700	CDD:213299	104/535 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342896
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930