Protein Alignment Fatp1 and SLC27A6

DIOPT Version :9

• Sequence 1: NP_001162940.3
• Gene: Fatp1 / 26067068
• FlyBaseID: FBgn0267828
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_001017372.1
• Gene: SLC27A6 / 28965
• HGNCID: 11000
• Length: 619
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 241/647 - (37%)
• Similarity: 358/647 - (55%)
• Gaps: 53/647 - (8%)

  Fly   121 MGWIFAVLVALVAL-----LLTKPGWR--WFYIAGATASRDLTALWAYIKLLRYTKRHERLNYTV 178
            :.|:..:...:|.|     ||....|.  ||.         |..:...|:|.:|.||.|.:  ||
Human     3 LSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFV---------LKVVLIIIRLKKYEKRGELV--TV 56

  Fly   179 ADVFERNVQAHPDKVAVVSETQRWTFRQVNEHANKVANV-LQAQGYKKGDVVALLLENRAEYVAT 242
            .|.|..:.:..|.|..::.|...:|::.|::.:::||:| |.....||||.||||:.|..::|..
Human    57 LDKFLSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHV 121

  Fly   243 WLGLSKIGVITPLINTNLRGPSLLHSITVAHCSALIYGEDFLEAVTDVAKDLPANLTLFQFNNEN 307
            |.||:|:|.:...:|||:|..|||:.|......||:.|.|.|..|.::...|..|::::...:
Human   122 WFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKD-- 184

  Fly   308 NNSETEKNIPQAK-NLNALLTTASYEKPNKTQVNHH------DKLVYIYTSGTTGLPKAAVISHS 365
                   ::||.. :|...|:|:..|...:   :||      ...:||:||||||||||||||..
Human   185 -------SVPQGVISLKEKLSTSPDEPVPR---SHHVVSLLKSTCLYIFTSGTTGLPKAAVISQL 239

  Fly   366 RYLFIAAGIHYTMGFQEEDIFYTPLPLYHTAGGIMCMGQSVLFGSTVSIRKKFSASNYFADCAKY 430
            :.| ..:.:.:..|....||.|..|||||::..|:.:...|..|:|..::||||||.:::||.||
Human   240 QVL-RGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKY 303

  Fly   431 NATIGQYIGEMARYILATKPSEYDQKHRVRLVFGNGLRPQIWPQFVQRFNIAKVGEFYGATEGNA 495
            :.|:.|||||:.||:......|.::.|:|||..|||:|..:|.:|:.||...||.|.|.|||.:.
Human   304 DVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSI 368

  Fly   496 NIMNHDNTVGAIGFVSRILPKIYPISIIRADPDTGEPIRDRNGLCQLCAPNEPGVFIGKIVKGNP 560
            :.||:...:||||..:.....:....:|:.|....||:|:..|.|......|||:.|.::...||
Human   369 SFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP 433

  Fly   561 SREFLGYVDE-KASAKKIVKDVFKHGDMAFISGDLLVADEKGYLYFKDRTGDTFRWKGENVSTSE 624
               |.||... |.:..|::.||||.||:...:|||:|.|:..:|||.||||||||||||||:|:|
Human   434 ---FFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTE 495

  Fly   625 VEAQVSNVAGYKDTV----VYGVTIPHTEGRAGMAA-IYDPERELDLDVFAASLAKVLPAYARPQ 684
                |::|.|..|.:    ||||.|...|||||||: |..|...|||:.....:...|||||.|:
Human   496 ----VADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPR 556

  Fly   685 IIRLLTKVDLTGTFKLRKVDLQKEGYDPNAIKDALYYQTS-KGRYELLTPQVYDQVQRNEIR 745
            .:|:..|::.||||||.|..|.::|::|..|.:.||:..: |..|.|||.::|||:...||:
Human   557 FLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIK 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp1	NP_001162940.3	PRK08279	153..746	CDD:236217	233/608 (38%)
		hsFATP4_like	199..712	CDD:213305	205/526 (39%)
SLC27A6	NP_001017372.1	PRK08279	16..619	CDD:236217	239/634 (38%)
		hsFATP2a_ACSVL_like	77..609	CDD:213304	214/551 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149033
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000388
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100576
Panther	1	1.100	-	-	O	PTHR43107
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2110
SonicParanoid	1	1.000	-	-		X222
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.870