Protein Alignment Fatp1 and SLC27A6

DIOPT Version :10

• Sequence 1: NP_001162940.3
• Gene: Fatp1 / 26067068
• FlyBaseID: FBgn0267828
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_054750.1
• Gene: SLC27A6 / 28965
• HGNCID: 11000
• Length: 619
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 241/647 - (37%)
• Similarity: 358/647 - (55%)
• Gaps: 53/647 - (8%)

  Fly   121 MGWIFAVLVALVAL-----LLTKPGWR--WFYIAGATASRDLTALWAYIKLLRYTKRHERLNYTV 178
            :.|:..:...:|.|     ||....|.  ||.         |..:...|:|.:|.||.|.:  ||
Human     3 LSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFV---------LKVVLIIIRLKKYEKRGELV--TV 56

  Fly   179 ADVFERNVQAHPDKVAVVSETQRWTFRQVNEHANKVANV-LQAQGYKKGDVVALLLENRAEYVAT 242
            .|.|..:.:..|.|..::.|...:|::.|::.:::||:| |.....||||.||||:.|..::|..
Human    57 LDKFLSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHV 121

  Fly   243 WLGLSKIGVITPLINTNLRGPSLLHSITVAHCSALIYGEDFLEAVTDVAKDLPANLTLFQFNNEN 307
            |.||:|:|.:...:|||:|..|||:.|......||:.|.|.|..|.::...|..|::::...:
Human   122 WFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKD-- 184

  Fly   308 NNSETEKNIPQAK-NLNALLTTASYEKPNKTQVNHH------DKLVYIYTSGTTGLPKAAVISHS 365
                   ::||.. :|...|:|:..|...:   :||      ...:||:||||||||||||||..
Human   185 -------SVPQGVISLKEKLSTSPDEPVPR---SHHVVSLLKSTCLYIFTSGTTGLPKAAVISQL 239

  Fly   366 RYLFIAAGIHYTMGFQEEDIFYTPLPLYHTAGGIMCMGQSVLFGSTVSIRKKFSASNYFADCAKY 430
            :.| ..:.:.:..|....||.|..|||||::..|:.:...|..|:|..::||||||.:::||.||
Human   240 QVL-RGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKY 303

  Fly   431 NATIGQYIGEMARYILATKPSEYDQKHRVRLVFGNGLRPQIWPQFVQRFNIAKVGEFYGATEGNA 495
            :.|:.|||||:.||:......|.::.|:|||..|||:|..:|.:|:.||...||.|.|.|||.:.
Human   304 DVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSI 368

  Fly   496 NIMNHDNTVGAIGFVSRILPKIYPISIIRADPDTGEPIRDRNGLCQLCAPNEPGVFIGKIVKGNP 560
            :.||:...:||||..:.....:....:|:.|....||:|:..|.|......|||:.|.::...||
Human   369 SFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP 433

  Fly   561 SREFLGYVDE-KASAKKIVKDVFKHGDMAFISGDLLVADEKGYLYFKDRTGDTFRWKGENVSTSE 624
               |.||... |.:..|::.||||.||:...:|||:|.|:..:|||.||||||||||||||:|:|
Human   434 ---FFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTE 495

  Fly   625 VEAQVSNVAGYKDTV----VYGVTIPHTEGRAGMAA-IYDPERELDLDVFAASLAKVLPAYARPQ 684
                |::|.|..|.:    ||||.|...|||||||: |..|...|||:.....:...|||||.|:
Human   496 ----VADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPR 556

  Fly   685 IIRLLTKVDLTGTFKLRKVDLQKEGYDPNAIKDALYYQTS-KGRYELLTPQVYDQVQRNEIR 745
            .:|:..|::.||||||.|..|.::|::|..|.:.||:..: |..|.|||.::|||:...||:
Human   557 FLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIK 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fatp1	NP_001162940.3	hsFATP4_like	199..712	CDD:341262	205/526 (39%)
SLC27A6	NP_054750.1	hsFATP2a_ACSVL_like	75..609	CDD:341261	215/553 (39%)