DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp1 and Acsl6

DIOPT Version :9

Sequence 1:	NP_001162940.3	Gene:	Fatp1 / 26067068	FlyBaseID:	FBgn0267828	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_030101662.1	Gene:	Acsl6 / 216739	MGIID:	894291	Length:	748	Species:	Mus musculus

Alignment Length:	835	Identity:	168/835 - (20%)
Similarity:	269/835 - (32%)	Gaps:	335/835 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 FRFFCATVAFGLAIACVIYTLHTMGWIFAVLVALVALLLT-KP--------------------GW 141
            ||...||            ||.::|    .|.|::|..|| :|                    |.
Mouse    47 FRSLSAT------------TLVSVG----ALAAVLAYWLTHRPKALQPPCNLLKQSEEVEDGGGA 95

  Fly   142 RWFYIAGATASRDLTALWAYIKLLRYTKRHERLNYTVADVFERNVQAHPDKVAV----VSETQRW 202
            |...|.|.|            :||.:.....|   |:..||.|.:....:...:    ..:..:|
Mouse    96 RRSVIGGCT------------QLLTHYYDDAR---TMYQVFRRGLSISGNGPCLGFRKPEQPYQW 145

  Fly   203 -TFRQVNEHANKVANVLQAQGYKKG--DVVALLLENRAEYVATWLGLSKIG-VITPLINTNLRGP 263
             ::::|.:.|..:.:.|.....|.|  ..|.:..:||.|::...|...... |:.||.:|  .||
Mouse   146 LSYQEVAKRAEFLGSGLLQHDCKVGTEQFVGVFAQNRPEWIIAELACYTYSMVVVPLYDT--LGP 208

  Fly   264 -SLLHSITVAH-CSALIYGEDFLEAVTDVAKDLPANLTLFQFNNENNNSETEKNIPQAKNLNAL- 325
             |:.:.|..|. |:.::              |.|...||...:.|      .|..|..|.:..:
Mouse   209 GSISYIINTADICTVIV--------------DKPHKATLLLEHVE------RKETPGLKLVILME 253

  Fly   326 -LTTASYEKPNKTQV--------------NHH--------DKLVYIYTSGTTGLPKAAVISH--- 364
             ...|..|:..|..|              |||        |..:..:||||||.||.|:::|
Mouse   254 PFEDALRERGKKCGVDIKSMQAIEDCGRENHHAPVPPRPDDLSIVCFTSGTTGNPKGAMLTHGNV 318

  Fly   365 ----SRYLFIAAGIHYTMGFQEEDIFYTPLPLYHTAGGIMCMGQSVLFGSTVSIRKKFSASNYFA 425
                |.:|.:...:.:.   :::|:..:.|||.|       |.:.|:            .|.:..
Mouse   319 VADFSGFLKVTEKVIFP---RQDDVLISFLPLAH-------MFERVI------------QSQWAP 361

  Fly   426 DCAKYNAT---IGQYIGEMARYILATKPSEYDQKHRVRLVFGN---------GLRPQIWPQFVQR 478
            .||..:.:   :......|.:.::      |....||....|:         .|||.|:|...:.
Mouse   362 TCADVHFSYLPLAHMFERMVQSVV------YCHGGRVGFFQGDIRLLSDDMKALRPTIFPVVPRL 420

  Fly   479 FNIAKVGEFYGA-----------------TEGNANIMNHD--------NTVGAI--GFVSRILPK 516
            .|......|:.|                 .|..:.|:.::        |.:.|.  |.|..|:..
Mouse   421 LNRMYDKIFHQADTSLKRWLLEFAAKRKQAEVRSGIIRNNSIWDELFFNKIQASLGGHVRMIVTG 485

  Fly   517 IYPISIIRADPDTGEPIRDRNGLCQL------------CAPNEPGVFIGKIVKGNP--------- 560
            ..|     |.|.....:|...| ||:            |....||.:....| |.|
Mouse   486 AAP-----ASPTVLGFLRAALG-CQVYEGYGQTECTAGCTFTTPGDWTSGHV-GAPLPCNHIKLV 543

  Fly   561 SREFLGYVDEKASAKKIVKDVFKHGDMAFISGDLLVADEKGYLYFKDR------------TGDTF 613
            ..|.|.|...|...:..||     |...|          ||||..:||            |||..
Mouse   544 DAEELNYWTCKGEGEICVK-----GPNVF----------KGYLKDEDRTKEALDSDGWLHTGDIG 593

  Fly   614 RW-------------------KGENVSTSEVE------AQVSNVAGYKDTV---VYGVTIPHTEG 650
            :|                   :||.|:..::|      ..|:.:..:.|::   :.|:.:|
Mouse   594 KWLPEGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSEPVAQIYVHGDSLKAFLVGIVVP---- 654

  Fly   651 RAGMAAIYDPERELDLDVFAASLAKVLPAYARPQIIRLLTKVDLTGTFK--LRKVDLQKEGYDPN 713
                    |||              |:|::|:        |..:.||::  ..|.:|:|
Mouse   655 --------DPE--------------VMPSWAQ--------KKGIEGTYQELCMKKELKK------ 683

  Fly   714 AIKD------------------ALY-----YQTSKGRYELLTPQVYDQVQRNEIR 745
            ||.|                  |:|     :....|   ||||.:  :.:|.|:|
Mouse   684 AILDDMVMLGKESGLHSFEQVKAIYIHCDMFSVQNG---LLTPTL--KAKRPELR 733

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp1	NP_001162940.3	PRK08279	153..746	CDD:236217	150/759 (20%)
Fatp1	NP_001162940.3	hsFATP4_like	199..712	CDD:213305	130/651 (20%)
Acsl6	XP_030101662.1	LC-FACS_euk	141..744	CDD:341250	143/710 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839094
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930