DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fatp1 and Acsl4

DIOPT Version :9

Sequence 1:	NP_001162940.3	Gene:	Fatp1 / 26067068	FlyBaseID:	FBgn0267828	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_006257376.1	Gene:	Acsl4 / 113976	RGDID:	69401	Length:	711	Species:	Rattus norvegicus

Alignment Length:	619	Identity:	136/619 - (21%)
Similarity:	232/619 - (37%)	Gaps:	141/619 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 RW-TFRQVNEHANKVANVLQAQGYKKGDVVALLLENRAEYVATWLGLSKIGVITPLINTNLRGPS 264
            :| .:.:||...|...:.|.|.|.|..:.:|:..|.|||::.......|.......:...|...:
  Rat   124 KWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEA 188

  Fly   265 LLHSITVAHCSALIYGEDFLEAVTDVAKDLPANLT---LFQFNNENNNSETEKNIPQAKNLNALL 326
            ::|.:..:..|.||...:.||:....|. |..|..   ::..|...|.:|    .|:...::::.
  Rat   189 VVHGLNESEASYLITSVELLESKLKAAL-LDINCVKHIIYVDNKTINRAE----YPEGLEIHSMQ 248

  Fly   327 TTASY-EKPNKTQV-----NHHDKLVYIYTSGTTGLPKAAVISHSRYLFIAAGI----HYTMGFQ 381
            :.... .||..:.:     ...|..:.:||||:||.||..::.||.   :.||:    ....|..
  Rat   249 SVEELGSKPENSSIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSN---LIAGMTGQCERIPGLG 310

  Fly   382 EEDIFYTPLPLYHT---AGGIMCM--GQSVLFGSTVSIR------KKFSASNYFADCAKYNATIG 435
            .:|.:...|||.|.   ...|.|.  |..:.:.|.:::.      ||.|.    .||.....|:.
  Rat   311 PKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSK----GDCTVLKPTLM 371

  Fly   436 QYIGEMARYI---LATKPSE------------YDQK------------------HRVRLVFGNGL 467
            ..:.|:...|   :.:|..|            ||.|                  .:|:.:.|..:
  Rat   372 AAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNV 436

  Fly   468 R------PQIWPQFVQRFNI---AKVGEFYGATE--GNANIMN-HDNTVGAIGFVSRILPKIYPI 520
            |      ..:.||..:..|:   ..:|:.||.||  |...:.. .|.|.|.:|     .|.|...
  Rat   437 RMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVG-----APLICCE 496

  Fly   521 SIIRADPDTGEPIRDRNGLCQLCAPNEPGVFIGKIVKGNPSREFLGYVDEKASAKKIVKD--VFK 583
            ..::...:.|..:.|:        ||..    |:||.|..:.. :||...:   :|..:|  |.:
  Rat   497 IKLKDWQEGGYTVHDK--------PNPR----GEIVIGGQNIS-MGYFKNE---EKTAEDYSVDE 545

  Fly   584 HGDMAFISGDLLVADEKGYLYFKDRTGDTFRWK-GENVSTSEVEAQVSN---------VAGYKDT 638
            :|...|.:||:......|.|...||..|..:.: ||.||..:|||.:.|         .|....:
  Rat   546 NGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQS 610

  Fly   639 VVYGVTIPH------------TEGRAGMAAIYDPERELDL--DVFAASLAKVLPAYARPQIIRLL 689
            .|....:|:            .|| :.:....:|..|.::  ::..|:.|..|..:..|..:||.
  Rat   611 YVISFVVPNQKKLTLLAQQKGVEG-SWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLS 674

  Fly   690 TKV------DLTGTFKLRKVDLQKEGYDPNAIKD 717
            .:.      .:|..|||::.:| |..|    :||
  Rat   675 PEPWTPETGLVTDAFKLKRKEL-KNHY----LKD 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fatp1	NP_001162940.3	PRK08279	153..746	CDD:236217	136/619 (22%)
Fatp1	NP_001162940.3	hsFATP4_like	199..712	CDD:213305	134/612 (22%)
Acsl4	XP_006257376.1	LC_FACS_euk1	121..696	CDD:341294	131/605 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342827
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930