Protein Alignment Tmc and Tmc6

DIOPT Version :9

• Sequence 1: NP_001303362.1
• Gene: Tmc / 26067066
• FlyBaseID: FBgn0267796
• Length: 2036
• Species: Drosophila melanogaster
• Sequence 2: NP_663414.3
• Gene: Tmc6 / 217353
• MGIID: 1098686
• Length: 810
• Species: Mus musculus
• Alignment Length: 345
• Identity: 89/345 - (25%)
• Similarity: 140/345 - (40%)
• Gaps: 94/345 - (27%)

  Fly  1209 LTPLERKQKRLKEVQLAI--------------------KQIQTNLTTMCWETSLGQELSKVIVFD 1253
            |..|||....:.||.:||                    :::.| |...|||..:||||.:.:|.|
Mouse   492 LATLERHDSPVLEVYMAICRNLILKMAVLGVLCYHWLGRRVAT-LQGQCWEDFVGQELYRFMVVD 555

  Fly  1254 GLMSIVAPLCIDFLRALFVRYVNQNWCWDMEKTFP--QYGDFKIAENILTLINNQGQVWMGIFFS 1316
            .:..:        |.:||...|   |....||...  |..:|.||.|:|.||..|...|:|:.||
Mouse   556 FIFML--------LDSLFGELV---WRLISEKKLKRGQKPEFDIARNVLDLIYGQTLTWLGVLFS 609

  Fly  1317 PGLVLINLVKLMIMMYF-RSWIVLTCNVPHEVVFKASKSNNFYLSLLL------TMLFLCVLPVG 1374
            |.|..:.:::|:.:.:. ::.::..|..|.. .:.||..:..:|:||.      ..:|||
Mouse   610 PLLPAVQILRLLFLFHIKKASLMANCQAPRR-PWLASHMSTVFLTLLCFPSFLGAAVFLC----- 668

  Fly  1375 YAIVWLRPSWHCGPFSEYNRIAEFITNTTRNALPKQLHEPLDYLTSSSTVIPLL----------- 1428
            ||:..:|||..||||...|.:.|..|...|.         |::..|.::.:|.|
Mouse   669 YAVWQVRPSSTCGPFRTLNTMYEAGTVWVRR---------LEHAGSGASWLPWLHHFLVENTFFL 724

  Fly  1429 ----LLLILIIYYLVSLTGALREANQDLRTQLQKEREEERKKIFKVPEVKQAEPTATTLTNRWRK 1489
                .||:.:||:.:.:....|:....|:.|::.|.|:   |||              |.|:...
Mouse   725 FLASALLLAVIYFNIQVVKGQRKVICLLKEQIRNEGED---KIF--------------LINKLHS 772

  Fly  1490 VLEASSPVTP------TQPP 1503
            |.|......|      |:||
Mouse   773 VYEEEGRSRPGRTQDTTEPP 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmc	NP_001303362.1	TMC	1242..1348	CDD:285101	31/108 (29%)
		DUF612	<1447..1844	CDD:282585	15/63 (24%)
Tmc6	NP_663414.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		TMC	539..645	CDD:369533	34/117 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	775..810		5/18 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849496
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840