DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG46026 and MUC21

DIOPT Version :9

Sequence 1:NP_001303496.1 Gene:CG46026 / 26067064 FlyBaseID:FBgn0267690 Length:666 Species:Drosophila melanogaster
Sequence 2:NP_001309300.2 Gene:MUC21 / 394263 HGNCID:21661 Length:626 Species:Homo sapiens


Alignment Length:549 Identity:228/549 - (41%)
Similarity:312/549 - (56%) Gaps:62/549 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   129 TSDPASTGSPTTSTTIPTTT--GSSTTSTAIPTST--GSPTTSTAIPTTTGSP--TTSTAIPTST 187
            ||..|:|||...|:...|.|  |||.||:.:.|:|  ||..||..:...|.|.  |||:.|.|:|
Human    27 TSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTAT 91

  Fly   188 ----EPATTSTAIPTSTGSPTTSTAIPTSTGSPTTSPAIPTSTTTTQ----TPIPTSTTTTTESS 244
                ..|::..:|.|::||.|||:...|:|.|.:::|:...||.|..    |....||.|.:|||
Human    92 NSEFSTASSGISIATNSGSSTTSSGASTATNSESSTPSSGASTVTNSGSSVTSSGASTATNSESS 156

  Fly   245 TTSTAIPPSTTTTTESSTTSTAIPTSTTTTTASSTTSTAIPSSTTTTTESSTTSTSIPTSTTSTT 309
            |.|:.  .||.|.:||||.|:.  .||.|.:.|||||:.  :||.|.:||||||:...|:|.|  
Human   157 TVSSR--ASTATNSESSTLSSG--ASTATNSDSSTTSSG--ASTATNSESSTTSSGASTATNS-- 213

  Fly   310 ESSTTSTAIPTSTTTTTASSTTSTAIPPSTTTTTESSTTSTALPTSTTTTTQSPTTSTAIPTTTT 374
            ||||.|:.  .||.|.:.|||||:.  .||.|.:||.|||..  ..|.|.::|.|||:.  .:|.
Human   214 ESSTVSSR--ASTATNSESSTTSSG--ASTATNSESRTTSNG--AGTATNSESSTTSSG--ASTA 270

  Fly   375 TTTESPTTSTAVPTSKTTTTETPTTSTAIPTSTTTTTESSTTSTAIPTSTTTTTESSTTSTAIPT 439
            |.::|.|.|:...|:  |.:|:.|||:.  .||.|.::|||||:.  ..|.|.:||||||:.  .
Human   271 TNSDSSTVSSGASTA--TNSESSTTSSG--ASTATNSDSSTTSSG--AGTATNSESSTTSSG--A 327

  Fly   440 STTTTTESSTTSTAIPTSTTTTTQSPTTSTAILTTTTTTTESPITSTAVPTSTTTTTETPTTSTA 504
            ||.|.:||||||:.  .||.|.:.|.|||:.  ..|.|.:||...|:.:  ||.|.:|:.|.|:.
Human   328 STATNSESSTTSSG--ASTATNSDSSTTSSG--AGTATNSESSTVSSGI--STVTNSESSTPSSG 386

  Fly   505 IPTSRTTTTESSTTSTPIPTSTTTTTASSTTSTAIPPSTTTTTESSTTSTAIPISTTTTTQSPTT 569
            ..|:  |.:||||||:  ..:|.|.:.|||.|:.  .||.|.:||||||:.  :||.|.::|.||
Human   387 ANTA--TNSESSTTSS--GANTATNSESSTVSSG--ASTATNSESSTTSSG--VSTATNSESSTT 443

  Fly   570 STAIPTTTTTTTESSTTSTAIPTSTTTTTASSTTSTAIPSSTTTTTESSTTSTAIPTSTTTTTES 634
            |:.  .:|.|.::|||||:  ..||.|.:.|||.|:.|  ||.|.:||||||:.  .:|.|.:.|
Human   444 SSG--ASTATNSDSSTTSS--EASTATNSESSTVSSGI--STVTNSESSTTSSG--ANTATNSGS 500

  Fly   635 STTSTAIPSSTTPTTLSPTTSTAIPTSTT 663
            |.||..  |.|...|...|||.:..|:.:
Human   501 SVTSAG--SGTAALTGMHTTSHSASTAVS 527

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG46026NP_001303496.1 None
MUC21NP_001309300.2 Epiglycanin_TR 32..97 CDD:310328 25/64 (39%)
Epiglycanin_TR 122..177 CDD:310328 22/58 (38%)
Epiglycanin_TR 362..417 CDD:310328 23/62 (37%)
Epiglycanin_C 524..622 CDD:317099 1/4 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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