DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kl-5 and Dhc16F

DIOPT Version :9

Sequence 1:	NP_001015499.4	Gene:	kl-5 / 26067054	FlyBaseID:	FBgn0267433	Length:	4559	Species:	Drosophila melanogaster
Sequence 2:	NP_523394.1	Gene:	Dhc16F / 32785	FlyBaseID:	FBgn0283476	Length:	4081	Species:	Drosophila melanogaster

Alignment Length:	4455	Identity:	1286/4455 - (28%)
Similarity:	2066/4455 - (46%)	Gaps:	785/4455 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   353 SLIDCVNRTVE-----PDSIF---------QGDVDEAYKKLDINMQHLEYYKLIYNECRNSLKKF 403
            |||..:|..:.     ||..|         ..:....|...::..:.|..|:..|...|:
  Fly   153 SLIPDLNLIINRMRNMPDDSFVYMDYMLPHDSEYFTPYSLREVEYKDLNTYEPFYTVTRH----- 212

  Fly   404 KIGTTFNSQDWTWH-QDEIFGRLDKFLVRLEELKDLFNTVRDFQKLEKIVMGGLKGRQITFALEK 467
              |.||      || .:..|..||::....::...:.. :|.|
  Fly   213 --GVTF------WHCSENFFTPLDQWQQEFKQFLSIIQ-IRSF---------------------- 246

  Fly   468 ILEEYNSIYREWTNI----------QYNPIDPDAENSLF----QRDRLSFKAKTDVME-RMVSFQ 517
                  ||:|.|...          :.|......:|:||    |..:...:.::|::: :.::|.
  Fly   247 ------SIFRLWKGFKVWEKTIKWRKLNEARDYLQNNLFIVIPQLAKAILRMRSDIVQLQRLNFV 305

  Fly   518 FEKGLEDTHDLLLAGSLLLRPIIKKH--VEPLMHVIVDDFEEEIMCVKKEFINFKNVFTALGLNE 580
            ....:|:.|...         .::.|  :...:|....||        :||| .|.:|.|
  Fly   306 NVSNIENWHPFY---------FLETHMRIYEQLHKTFTDF--------REFI-AKTIFRA----- 347

  Fly   581 LPTDDCFPKVSGAISFLKKLRHRIIGLHKEHELYEYPLFDNERGGYVSDIFNIMVQEIDDFTKML 645
                 |...:...            |.:.:.|:..||.....|..:         ..:|...|..
  Fly   348 -----CTDAIQAR------------GFYPDDEVNYYPSLKKMREAH---------SFMDRARKRA 386

  Fly   646 LDKWTVECWQGIQQDITLTLIEKDEANELRVNFTERLIFALKDIKVVRLLGCDVSV--------- 701
            ..|             |||            ||               |..||:.|
  Fly   387 FCK-------------TLT------------NF---------------LTYCDMMVYQMLYRITK 411

  Fly   702 ----NLTKFFCREDELWQARVKLMRIAEWYNDTFERAHPTEKRLIAAEMILIEEQM---KPLLDF 759
                :|...|...||:..:...:           .:....:||        ||:|.   ||...|
  Fly   412 KSFEDLATSFEVHDEVGPSEADI-----------NKHDRVDKR--------IEKQRPQDKPQSPF 457

  Fly   760 IKWNAFSQRFIVMIFKMVKYLHDRLVAAQENLEAIKESIRSWGKVPLFQRKD---LNPALLLH-- 819
                     |:.|:    :.|.||:     ::|..::.||.     :|||..   |...|.:|
  Fly   458 ---------FLAML----RLLPDRI-----DIEPSEDIIRI-----IFQRITGLILETVLEIHPF 499

  Fly   820 -TDPREPILSIRAANAADTQRLIDLLMYVNLKLFFDIPRRYSLPPGEHGEEDEESDGIWPPIISL 883
             |||                             ||   .:|:.|.....:|:...:|  .|.:..
  Fly   500 TTDP-----------------------------FF---TQYTQPSIMGRQEEVLYEG--APDLHY 530

  Fly   884 SVMTSVKFKKKREVIDEEDDLEEFEEEQSESEEEIITPFHRYELLKGLSQEERALFREYEIYVDE 948
            .:...::|:..|:                          :.:.|:       |..:....:|...
  Fly   531 LLRADIRFQYNRK--------------------------NMFVLI-------RKAYERARLYTQR 562

  Fly   949 I--IAENLVDSVITSSTYLRMEVD--------NRYENNTPIFEIFMELQEPNVVYFRNLDTSSKT 1003
            .  |.||......|..|.|..|.|        :||.||....:..:|      ..|..|...::|
  Fly   563 FHQIRENFEIDNSTDPTVLNTERDLQILRAYCDRYCNNVRALDGILE------YVFLGLLKLTQT 621

  Fly  1004 GFAFFIETILDDMNNMM-SLLKRVAQDPTEVTNMNPYSFYDELQDKSEL----DKQRVEIMNKIK 1063
            .|...:..:...:.|:: :.|.::|::  |.|.:     |:|.||....    ..:.:||:..|:
  Fly   622 NFKDTVTPVCSRLQNVLATYLPKLAEE--ETTRL-----YEEAQDFHGRICYEPHETLEIVAHIR 679

  Fly  1064 LALQAVRVHGKGFMEFSSL---WIWDKSTYLSE----VKKFGRNLTLDERDAEADLEGSSGVKLL 1121
                        |::..|.   .|:|...|:.:    :|.||..:..|.::...|.|
  Fly   680 ------------FLDKCSTELDGIFDGIDYVHDLLLIIKDFGIPIDDDSKEDYMDTE-------- 724

  Fly  1122 GLEYPPLSVYKEQLDKFIELQDQIRTWETYEDFFVFLRLNMTGFKVAVLSQVGQWISLFKLDLIN 1186
                                                                         |.:|
  Fly   725 -------------------------------------------------------------DYLN 728

  Fly  1187 RVKNSLKEL----QDFVDEANIVLKIELQKDDFEGLVKILSVLNQINEKQCIYDSMFDPLKEIID 1247
            |.:.:|:|:    |||::...     :..:||...|            |:.|::       ..|:
  Fly   729 RTRETLEEIREKRQDFINRLE-----DAMQDDIAAL------------KEDIHE-------VAIE 769

  Fly  1248 LLRQYNYEFKDTELAQINELPDAWMKVKRLAATTKQLIAPIQSYQVDLIEKRILLCDNMANTYRK 1312
            .|:.:..:.....|:..|:|.....::.:...|..:.:...:.:|:||     .:.|.||:.:
  Fly   770 ALQPWLLDANSNRLSVTNKLDSMLERLNKCRETADEFLGYQKEFQIDL-----TMYDEMASGF-- 827

  Fly  1313 KFLSKKFFFVPCLSCYELIDESDLELVALEERQRSLAESAVLFELQGPDPVKIELCRFDLKLVKI 1377
                                                                     :|:::.:
  Fly   828 ---------------------------------------------------------YDIRMRQ- 834

  Fly  1378 MWDFAITIQSTINDWKKT--PWKKIDIENMD------------QECKKFGRELRGLDKAMRTWEP 1428
                  .:..|.:||:::  .|...|...::            :.|.:|.:.|.         |.
  Fly   835 ------NLYRTWSDWEESLAEWIVSDFNTLNVVDMVELNSKTIKNCMQFQKYLP---------EN 884

  Fly  1429 FI--FMEASLKNLMTSLRAVTELQNPAIRDRHWIELMQTTKVKFSMDDSTTLKDLIDLNLHEYE- 1490
            .|  .::.|.:.....|..:..|:||.:|.|||.|:......||..:....::...|  :|.::
  Fly   885 NIVPVLQKSAEAFKEKLPVIGYLRNPNLRARHWAEIEDLLNRKFFQEKDILIQTYED--VHAFDD 947

  Fly  1491 ----EEVKNIVDKSVKEMAMEKQLRDIATAWGTMEFG-TDIHDRTSIKLLKASEELIETLEDHQG 1550
                |.:..|..::..|:.:|..|:.|.|.|...|.. ...||...:.:|..:|||...|:|...
  Fly   948 VAIGEALMQISSQATGEVQLENMLKGIETTWKETELSIVPHHDAKDVFILAGTEELQAVLDDSNV 1012

  Fly  1551 QLQNMASSKYIAFFEHEVRLWQNRLSNADQIIGSWFEVQRKWQYLESIFIGSEDIRSQLPEDSRR 1615
            .:..:|:||::...:.:|..|.|.:....:...||.:.|..|.|||:|| .|.||:.|||.:::.
  Fly  1013 NINTIAASKFVGPIKSKVDEWINAMDQFAKTFESWMDCQGAWIYLEAIF-ASADIQRQLPHEAKM 1076

  Fly  1616 FDYIDKEFKALLAQMNADRNVVRSTNRSGSKLYEHLEILLKMLLLCEKALNDYLETKRLSYPRFY 1680
            |..:||.||..:.|  |.:..:.....|...:::.|....::|.|..:.|..|||.||:.:||||
  Fly  1077 FFTVDKSFKETVRQ--AKKVALALPTMSSVDVHKVLVENNRLLDLISRGLEAYLEVKRVVFPRFY 1139

  Fly  1681 FVSSADLLDILSNGNNPALVARHLTKLYDSMGKLNLISGSKNAAG--MVAKELEEYVPFL----- 1738
            |:|:.:||:||:....|..|..||.|.:|::.:|..  |||....  |||  ..:.|.||
  Fly  1140 FLSNDELLEILAQTRIPQAVQPHLRKCFDAIYRLEF--GSKEGGDGKMVA--TNDIVAFLSPEGE 1200

  Fly  1739 -----ENCDCSGKVEVWLNRITDKMRDTLRDQLKRSLTFYDHKPRHVWIFEWPAQPALVGTQIMW 1798
                 :.....|.||.||:::.:.|..:.:..::.....|..|.|..|..:.|.|..|..:|:.|
  Fly  1201 KLQFGKGLKARGAVEEWLSKVEEAMFVSCKRYMRFGYQCYPAKEREDWFQDHPNQVVLTVSQVQW 1265

  Fly  1799 TTETNDAFAKVQQRYENALKDYNKKQITQLNNLIILLLGDLTAAERQKIMT-----IC---TIDV 1855
            ..:.:..:...::...|.|:...|.:|..|.:     ||.|.|..|:.|.:     :|   ||||
  Fly  1266 AADIHRIYEGKERNPLNILEKMAKFEIKCLKD-----LGALAALTRKNISSLLRKILCALITIDV 1325

  Fly  1856 HSRDVVGTIIAKKVEVQTAFQWQSQLRHRWDPKIDDCFANICDAQFRYDYEYLGNTPRLVITPLT 1920
            |::|.|..:|.|:|...:.|.|...||..|..:.:..::.:..|...|.|||||....||:||||
  Fly  1326 HAKDSVRMLIEKEVCKASDFNWLKMLRFYWADETETVYSRMAAANIPYYYEYLGAGGVLVLTPLT 1390

  Fly  1921 DRCYITLTQSLHLVMGGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGDIHKGLAQ 1985
            ||||:.|..:..:.:|||||||||||||||||||.:||.....|||||:.:|||.:|....||||
  Fly  1391 DRCYLCLMGAFQMDLGGAPAGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKMMGRFFSGLAQ 1455

  Fly  1986 TGAWGCFDEFNRISVEVLSVVAVQVKCIQDAIKSKKQTFSFLGEHIALRTTVGVFITMNPGYAGR 2050
            .|||.||||||||.:|||||:|.|:..|:.|...:.:.|.|.|..|.:..:..||||||||||||
  Fly  1456 CGAWCCFDEFNRIDIEVLSVIAQQLITIRTAKAMRVKRFIFEGREIKINRSCCVFITMNPGYAGR 1520

  Fly  2051 AELPENLKALYRPCAMVVPDFALISEIMLVAEGFQEARLLARKFITLYTLCKELLSKQDHYDWGL 2115
            .|||:|||||:||.:|:|||:|||||::|.:|||::.::||||.:.:|.||.:.||:|:|||:|:
  Fly  1521 TELPDNLKALFRPISMMVPDYALISEVILYSEGFEDPKILARKMVQMYQLCSQQLSQQNHYDFGM 1585

  Fly  2116 RAIKSVLVVAGALRRDDRQRPEDQVLMRALRDFNIPKIVTDDVPVFMGLIGDLFPALDVPRKRNP 2180
            ||:|||||:||||:|....:.||..|:.||||.||||.:.||..:|.|::.||||.:::|..::|
  Fly  1586 RAVKSVLVMAGALKRASPNQREDITLIAALRDSNIPKFLADDAVLFRGILSDLFPGVELPDSQHP 1650

  Fly  2181 EFEAVIKRSALDLKLQPEDGFILKIVQLEELFAVRHSVFIIGFAGTGKSEVWK----TLNKTYQN 2241
            ..||.::.......||.....|.|.:||.|...||..|.::|..|.|||.|..    .|:..::|
  Fly  1651 HLEASLRLGLRQKNLQAVPTTIRKCLQLYETMCVRWGVMLVGPTGGGKSVVLHALEFALSHLFEN 1715

  Fly  2242 QKRKPHY-----NDLNPKAVTNDELFGIVNPSTREWKDGLFSILMRDQANLGGTGPKWIVLDGDI 2301
            :.:.|::     ..:||||||.:||:|.|:..|.||:|||..:.:|....:.....:||:.||.:
  Fly  1716 EVQDPNFRPVVIQTMNPKAVTMNELYGYVDLKTLEWQDGLLGLAVRTATTVEDEIHQWIMCDGPV 1780

  Fly  2302 DPMWIESLNTVMDDNKVLTLASNERIALTKEMRLLFEIASLRTATPATVSRAGILYINPQDLGWT 2366
            |.:|||:||||:||||:|.||::|||.||..:.:|||:..|..|:||||||.|::|::|.||||.
  Fly  1781 DAVWIENLNTVLDDNKMLCLANSERIKLTAWIHMLFEVQDLLQASPATVSRCGMVYVDPGDLGWI 1845

  Fly  2367 PFIQSWLGTRTNSSEVSMLN-----------VLFDKYVPPLLDIFRTRLRSITPISDI--ARLQM 2418
            |.|.:|       .||.|.:           .||..|....|.|  .|.|::..|..:  :::::
  Fly  1846 PLIDTW-------REVDMKHKLPAPLAEFCYQLFVGYFDKALKI--ERKRAVYTIHQVLGSKVRL 1901

  Fly  2419 TCYLLDSMLTP---QNVPNDCPKDWYEIYFVFCIVWGFGSSLFQDQIIDWSNEFSKWFLNEYKAV 2480
            .|.|..:....   ..:..:..|:.....|.:.::|...|:|...:.:.:..::|| .:.::..:
  Fly  1902 CCELNSAQFEAVKWSAMSEEQGKELVTKIFAWAVLWAIASNLKDAEKVSFEEQWSK-AIAQHPNM 1965

  Fly  2481 KFPLSGTIFSFYIDHETKKFFPWTNLVPQFELDMDLPLQSNLVNTAETTRLRFFMDTLIEADHPL 2545
            ..| :.|::::.||.|...:..|.:::.:|..|.:.......|.|.:||:..:..|.|.:...|:
  Fly  1966 TLP-NFTLWNYRIDLEKMDWGSWIDIMAKFVFDPETSYYDMQVPTVDTTKYGYVSDLLFKRGMPV 2029

  Fly  2546 MLIGPSGSGKTILMNAKLSALPSDKYSVTNVPFNFYTTSEMLQRILEKPLEKKAGRNYG-PIGNK 2609
            |:.|.:|.|||:|..:.:..|.........:.|:..|:|...|.::|.||||:.....| |:| |
  Fly  2030 MVTGDTGVGKTVLAISCMKRLSQGNVIPVILNFSAQTSSNRTQEMIEGPLEKRKKTQLGAPVG-K 2093

  Fly  2610 RMIYFVDDMNMPEVDKYFTVQPHTLIRQFMDYHHWYDRQKMTLRDIHKCNIV---ACMNPSAGSF 2671
            .:|.|:||:|||::|.|.......|:|||:|:..:|||:|:..::|  .::|   ||..|..|..
  Fly  2094 TVIVFIDDVNMPKLDTYGASPAIELLRQFLDFKGFYDREKLYWKEI--LDVVLGCACAPPGGGRN 2156

  Fly  2672 TIDPRLQRHFCSFAVNPPSQDALFHILNSILSQHMDNPIQKFDKAVIKLCENMVTTAITLHLKVV 2736
            .:.||..|||..|::..|:::.|..|.|.||...    :|.|..||..|.|.||...:.::::|.
  Fly  2157 PLTPRFVRHFALFSLPKPNEETLTQIFNGILRGF----LQTFSSAVRALSEPMVNACVDVYMRVA 2217

  Fly  2737 SSFLPTAIKFHYNFNLRDIANIFTGVLYSNSETCPNSNQMIRLWIHECYRVYGDKLVDYTDINSF 2801
            :..|||..|.||.|||||::....|:|.:::......||::||:.||..||:.|:|::..|.|.|
  Fly  2218 TVMLPTPDKSHYIFNLRDLSKCIQGILQASNLHYNQENQILRLFYHETTRVFHDRLINIEDKNIF 2282

  Fly  2802 KKIVSDIVRKGIEG--VNDDVVYAQPLIYCHFAKGLTDIKYMPISGWDRLKSLLDEAQDR----- 2859
            |.::.::.......  :||:   ..|:::..|.          :.|..:.:.:.||.:|.
  Fly  2283 KALMKEVCMDHFNRPVINDN---EPPILFGDFM----------VFGKPKNERIYDEIRDHTKLES 2334

  Fly  2860 -YNDYIG---------AMNLVLFDDAMSHVCRISRILESSRGYALLIGVGGSGKQSLTRLASFIS 2914
             .||||.         .|.|:||.|||.|..|::|:|.|.||..||:||.|.||||||||||.::
  Fly  2335 VLNDYIADYNSVAVGKQMKLILFQDAMEHTVRLARLLRSDRGNGLLVGVAGMGKQSLTRLASHVN 2399

  Fly  2915 SLDVFQIQLTKDYSVSDLKANIATLYMKAGVKTSACCFLMTDSEVAREQFLVLVNDLLASGDIHE 2979
            ..:.:||::.::|.::....::..||..||:......||:.||::..|:||..:|::|.||::..
  Fly  2400 EYNCWQIEMRRNYDLNAFHEDLRVLYRIAGIDNQPVTFLLIDSQIVEEEFLEDINNILNSGEVPN 2464

  Fly  2980 LFPDDEVENIVNAVRNEVKQLGIVDN-------RENCWKYFIEKVRSLLKVVLCFSPVGATLRVR 3037
            ||..||.|.|:...|:     |..:|       |::.:|:||.:||:.|.||:..||||...|.|
  Fly  2465 LFEGDEFEKIILDARD-----GCNENRKDDPCTRDDIYKFFINRVRNNLHVVMSMSPVGDAFRRR 2524

  Fly  3038 SRKFPALVNCTTIDWFHEWPQQALESVSLRFLSEITVLPK-ELALPVSNFMAFVHKTVNDISKLY 3101
            .|.||:||||||||||..||.:||.||:|..|::|.  || |..:.:::...|:||||.|.|..:
  Fly  2525 CRMFPSLVNCTTIDWFTSWPTEALYSVALGLLTKIA--PKMEDRISLASTTVFMHKTVEDASVKF 2587

  Fly  3102 LANAKRYNYTTPKSFLELIALYSKLLHEKVKANLDRRLRLENGLIKLASCTKEVDALQDVLKVQE 3166
            ....||:.||||.|:|||:.||..||..|....:.:|.|:.|||.||....:.:..:...|:|..
  Fly  2588 YKEMKRHYYTTPSSYLELLKLYQNLLKIKNMEIIAKRKRIANGLNKLLETNEVIAVMGKELEVMV 2652

  Fly  3167 VELKIKNQEADNLIIVVGTENEKVSKERAFASKEEKNVRQ--IEEDVTAK-----AKLCEEDFLK 3224
            .:|..|:....:|:       :.::||    :|:...|:|  :|:::.||     |:...||..|
  Fly  2653 PQLDEKSAMMKSLV-------DNLTKE----TKQADAVKQSVLEDEMNAKEKAAVAQAISEDAGK 2706

  Fly  3225 ----AQPALIAAQEALNTLNKNNLTELKSFGSPPDAVVSVC-GAVLVLFSSKGKIPKDRSWKACR 3284
                |.|||..|:|||..|.|.::.|||||.:|| |:|..| .||.:|...|      .:|.:.:
  Fly  2707 DLEIAMPALREAEEALKGLTKADINELKSFTTPP-ALVQFCMEAVCILLGVK------PTWASAK 2764

  Fly  3285 AFMGNVDKFLDNLINYDKKHIHPDVIKALQPYILDAEFSPEKILAKSSAAAGLCSWVININRFYD 3349
            |.|.::: |:..|..|||:|:..|.:|.::.||...:|.|.|....|..|..:..|||::::|..
  Fly  2765 AIMADIN-FIKRLFEYDKEHMKEDTLKKVKKYIDHKDFVPAKFEKVSKVAKSMSMWVISMDKFSK 2828

  Fly  3350 VYLVVEPKERALLESEKEVKDARDKLTALNLRLTELEEQLNALQMEYDEALAKKQKCQDEASKTA 3414
            ||.|||||.:....:|.|:|:....|......|..:|.::..|:...:|...:.|..||....|.
  Fly  2829 VYKVVEPKIKRKEAAEAELKEVMTVLRQKQKELAAVEAKIQGLRDSLEEKQREFQVIQDNVDLTY 2893

  Fly  3415 FTIDIANRLIGGLATEKIRWMESVKVLTFGIQQLPGDILIISCFISYVGCFTRAYRQELQEKLWM 3479
            ..|:.|.||...|:.|::||.|:||.||..:..:|||:|:.:..::|:|.|:..||::: ..||:
  Fly  2894 GRINRAGRLTSALSDEQVRWRETVKSLTGDLACVPGDVLVAAACVAYLGAFSHEYRRDM-SALWV 2957

  Fly  3480 PAFKNSQPPIPSTDGVDPFEMICDDAQIAEWNNQGLPSDRMSAENAAILVQSERYPLMIDPQLQG 3544
            .  |..:..|||:...:..:::.|..::.:||..|||.|.:|.||.....::.|:.||||||.|.
  Fly  2958 S--KCREHKIPSSPEFNLLKVLGDPYEMRQWNVDGLPKDNISIENGIYATRALRWALMIDPQEQA 3020

  Fly  3545 IKWVKT-KYGTGLVVLRLSQRNYLDQVERAVSNGSVLLIENIGENIDPVLNPLLGRQLIK-KG-T 3606
            .:|::. :....|.|::::....:..:|.||..|..:|:|.|.|.|||.|.|:|.|:..: :| |
  Fly  3021 NRWIRNMERANNLQVIKMTDSTMMRVLENAVRQGYPVLLEEINETIDPSLRPILQRETYRFEGRT 3085

  Fly  3607 VLKIGDREIDFNSRFRLILHTKLANPHYKPEMQAQTTLINFTVTRDGLEDQLLAEVVKVERPDLE 3671
            .||:||..||::..|:|.:.|||.||||.||:....||:||.||..||||||||::|.:|.|.:|
  Fly  3086 YLKLGDMVIDYDDNFKLYMTTKLPNPHYLPEVCINVTLVNFLVTESGLEDQLLADIVAIELPAME 3150

  Fly  3672 AMRTRLTQQQNHFKITLKFLEDDLLARLSSAGDNVLEDVTLVMNLEKTKKTADEIEVKVAEAKIT 3736
            ..|..|..:.|..|..|..|||.:|..|.::..|:|:|..||..|...|:|:..|..::.:.:.|
  Fly  3151 IQRNDLVVKINSDKQQLLALEDKVLKLLFNSEGNILDDEELVETLNDAKETSLIIAARLIDTEET 3215

  Fly  3737 GVQIDSAREAYRPAAERASIIYFILNDLFKINPIYQFSLKAFTVVFNNAMLKAMAAEKLKDRVEN 3801
            ...|.::||.||..|.|.:|:||::..|.:|:|:||:|||.||.||.|.:......:.::.|:..
  Fly  3216 EKVITASRERYRILASRGAILYFVVAGLAEIDPMYQYSLKYFTQVFCNVLRLDHPPQSVEVRIST 3280

  Fly  3802 LIDSITFCSFVYTSRGLFEQDKLIFLTQLCIQILVNLGEVEPTELDFLLRFP-------YMPNQT 3859
            |:.......|...||||||..|:||...|.:.:....|.|...|..||.|.|       ..|.:.
  Fly  3281 LMTDELRAIFDNISRGLFENHKIIFSFLLALSVERQEGRVTEEEFLFLSRGPVGNIRTKIQPAKI 3345

  Fly  3860 SNFTWLTHVGWGGIRAL--NNQAVFKGLEKDIE-------GSHKRWKKFVDSESPENEKFPGEW- 3914
            .    ::.:.|.....|  |..:.|.||..:::       ..:|....|..:..|..:|    |
  Fly  3346 K----MSQIEWDSCIFLEDNFSSFFSGLTDELDKPFFIQMQENKEVFDFAQTNQPPTDK----WN 3402

  Fly  3915 KGKSAIQRLCIMRCIRPDRMSYAMRSFIEEKLGSKYIDAR-SMEFSRTFEESSPETHIFFVLSPG 3978
            |......:|..:...|..|....:..:::..:|..:.:|. ..:.|..:.::|..|.:.||||.|
  Fly  3403 KRLRVFHKLMFISAFRKPRFLLNVVCYLQSTVGKYFTEASGGTQLSSVYLDTSAVTPLIFVLSTG 3467

  Fly  3979 VDPLKDVEKLGKSLGFSFDHENFHSVSLGQGQEIVAENAIEIASQYGHWVILQNIHLVARWLPSL 4043
            .||:....|....:.|:   :.::|:||||||..:|||.||.:.:.||||.|||.||...::.:|
  Fly  3468 SDPMSGFLKFTTQMQFT---DKYYSISLGQGQGPLAENLIEKSLRLGHWVFLQNCHLATSFMQTL 3529

  Fly  4044 E---KKMESSLSNVHTSYRLFLSAEPAGDPAAHILPQGILESAIKITNEPPTGMMANIHKALDNF 4105
            |   :.:...::..|..:||:||:.|     ....|..:|::::|||||||.|:.||:..||.:.
  Fly  3530 ETIVRNLTLGITKAHVDFRLYLSSMP-----IQTFPISVLQNSVKITNEPPKGIKANVFGALTDL 3589

  Fly  4106 SDETLEMCSKETEFKAILFSLCYFHAVVAERRKFGPQGWNRSYPFNVGDLTISVYVLYNYL--EA 4168
            ..:..|...:...::||:|.||.||||:.|||||||.|||.:|.|:..|....:..|..::  |.
  Fly  3590 KQDFFEQHIQNGNWRAIVFGLCMFHAVLLERRKFGPLGWNITYEFSESDRECGLKTLDFFIDREV 3654

  Fly  4169 NTRVPWEDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFMQPELIDGELEYCQG---FPAPGILKY 4230
            ...:|||.:.|:.|:|.:||.:||.||.|..||.|..|....:|..:.:||:|   :..|.....
  Fly  3655 LDEIPWEAILYINGDITWGGRVTDYWDLRCLRTILTIFSSKRIIQPDYKYCRGDSYYRDPRKKTL 3719

  Fly  4231 TGYHNYIDDNLPSESPSLYGLHSNAEIGFLTTVSERLFRIVFELQPRMTG--GSSGGETVSQEDI 4293
            |.|..|:......|.|.::|::.||.|.|.|..:......:...|||...  |.:....::|:.|
  Fly  3720 TEYSAYVQGFPVLEDPEIFGMNQNANIVFQTKETAFFINTLLLGQPRSAADEGQAMENEIAQQTI 3784

  Fly  4294 --IKNIIEDILDKTP--TPFNILELMGRVEDRSPYIIVAFQECERMNNLMTELKRSLNELDLGLK 4354
              |:..:...:.:.|  ...::|:..|:|...:   ||..||.:|.|..:..:..||..|...:|
  Fly  3785 ARIQKALATKIKREPIHDTLSVLDAKGQVPSLT---IVLVQEIDRFNIALGIIHDSLVNLSKAIK 3846

  Fly  4355 GELTISSVMEDLMVCLYMDQVPEQWTKLAYPSMLGLQSWFSDLMLRLRELEGWVADFRMPSSIWL 4419
            |.:.:|..:|::...|..:|||..|.|.::.|:..|.|:.||...|:..::.| |:...|.|.|:
  Fly  3847 GLVVMSEELENVFKALLSNQVPASWAKRSFLSIKPLPSYISDFQRRIDFIQQW-AENGAPRSYWI 3910

  Fly  4420 AGFFNPQSLLTAIMQQTARKNEWPLDRMCLNCDVTKK-------WKEELTTAPREGAY------- 4470
            :|||.|||.||.::|..||:...|:|.:.::.||.::       ::........:..|
  Fly  3911 SGFFFPQSFLTGVLQTYARRRVLPIDSLKIDFDVFERELVQQDFFEMHTNNMSDQKLYGNLPECT 3975

  Fly  4471 -----INGLFMEGARWDMKMGTIADAFLKELFPAMPVLYIKAVTQDKQDIKNVYECPVYKIRLR- 4529
                 ::|:|:|.||||:..|.:.||...|||..|||:..|...:....::  ||.|:||.:.|
  Fly  3976 DAIINVHGIFIEAARWDLSKGGLCDANFGELFSRMPVVRFKPCLEISPTVR--YEAPLYKTQQRS 4038

  Fly  4530 --------GPTFVWTFNLKSRERASKWTLAGVCLL 4556
                    ...|:....|:|......|.:.|..|:
  Fly  4039 GVLSTTGHSTNFILAVLLRSHNDPEFWIMRGTALV 4073

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kl-5	NP_001015499.4	DHC_N1	197..763	CDD:285571	75/457 (16%)
		DHC_N2	1368..1770	CDD:285579	112/435 (26%)
		P-loop_NTPase	1903..2132	CDD:304359	136/228 (60%)
		P-loop_NTPase	2217..2352	CDD:304359	60/143 (42%)
		P-loop_NTPase	2510..2783	CDD:304359	92/276 (33%)
		P-loop_NTPase	2860..3127	CDD:304359	119/283 (42%)
		MT	3140..3480	CDD:289543	112/351 (32%)
		AAA_9	3509..3722	CDD:289547	89/215 (41%)
		Dynein_heavy	3864..4549	CDD:281078	213/737 (29%)
Dhc16F	NP_523394.1	DHC_N2	829..1234	CDD:285579	112/429 (26%)
		P-loop_NTPase	1373..1603	CDD:304359	136/229 (59%)
		P-loop_NTPase	1687..1832	CDD:304359	61/144 (42%)
		P-loop_NTPase	1994..2264	CDD:304359	92/276 (33%)
		P-loop_NTPase	2343..2613	CDD:304359	115/276 (42%)
		MT	2625..2957	CDD:289543	111/351 (32%)
		AAA_9	2985..3201	CDD:289547	89/215 (41%)
		Dynein_heavy	3342..4066	CDD:281078	214/745 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450577
Domainoid	1	1.000	49	1.000	Domainoid score	I7912
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1492at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47047
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.750