DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kl-3 and Dnah14

DIOPT Version :9

Sequence 1:	NP_001104482.3	Gene:	kl-3 / 26067053	FlyBaseID:	FBgn0267432	Length:	4593	Species:	Drosophila melanogaster
Sequence 2:	NP_001363968.1	Gene:	Dnah14 / 240960	MGIID:	2444525	Length:	4599	Species:	Mus musculus

Alignment Length:	4724	Identity:	1167/4724 - (24%)
Similarity:	2065/4724 - (43%)	Gaps:	955/4724 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   584 DRRYLEVAEMLEREMFLLKDVYNEE-----RGNPFIPRNLPPVA---------GRIIWI------ 628
            ||...|.|:.: :.:|.|::....|     |...:.|:.:.|..         |..|:.
Mouse   112 DRAEPEEADAI-KHIFRLREKLGWETPSFLRSLKYHPKTVLPRCSLKECLKDDGEFIYCLPMEND 175

  Fly   629 RSIFKKIDLPMQALKLRQCVLAHKKAQRTVRYYNYMNGIICHYEMAYHKAWFDYVEEVRCLLNAP 693
            |.:|.:.||        |.|.|| :|:....::.    :...:.....|...: :|:|..:   |
Mouse   176 RGMFNEYDL--------QAVSAH-RAKSCKEFWM----VTASFVSKITKTGLN-MEDVELM---P 223

  Fly   694 IM----------TINKEEAIYIVNIDRAILQLISETEWMWKLNLEVPNMAATITY------CKDR 742
            .|          .:.|.:..|...:::|.:        .||||::......:.:|      |.|.
Mouse   224 TMDWLYERHYFYLLQKFKIFYNFRLNKAFV--------TWKLNVKRRKTETSRSYLYNHLFCADE 280

  Fly   743 LL-----------GPATTLK---------LMLQRYDRLRTSL------------TPVFINIMRFR 775
            |.           ..|.|||         :.|.:.|..||.:            |.....:...|
Mouse   281 LFQTSLLYVRGLCEDALTLKKKNKDNSSTICLIKVDTSRTHVLEKFCEEQLQQATQAVAQLEEIR 345

  Fly   776 LQEISILLKPSLSTVTWISENLEDYVEKVCMKIKEVET-------FFNLILDIEDLRILQEMYSI 833
            .:.|..:.|.:|....  .:|:::|.|.   |..|:.|       :.||:  ..:||.|:    :
Mouse   346 SKAIVEIKKSALKVAE--KKNVKEYFES---KPSEINTTHFKLPQYRNLL--ETNLRFLK----L 399

  Fly   834 SDYLYIYVPEEPVSSYEFVEESNKLRSEIERILEKKSVCMERAVVDIINMFIDLLDFEQTDSKGR 898
            .|||:                     .|:.|.|      |..|:..::::|           .|.
Mouse   400 IDYLF---------------------QELIRQL------MNSALTQLLDLF-----------TGS 426

  Fly   899 RVFQLPPEKLNDTNWRTEGFLPIDKWDFIQFHKIY-RTIYLAPEDVLRTLQFRNYENIR------ 956
            .......||.|::..||           .:..||: |......|.||.:|...::::.:
Mouse   427 ARMPFSKEKKNESLMRT-----------FRDRKIFSRKESDDDEFVLSSLTAPSFQSSQPKLDTD 480

  Fly   957 -YELYHLRNDCMDLFSYYNS--KIILAL-----------VAGSKRSLDFVRQNI------LRTNW 1001
             .|.::.....|||...|..  :|.|.|           :.|:.:..:...:::      |....
Mouse   481 VKETFNSHRVAMDLKKTYAPIFEISLCLRLPTMNDSPEDLEGNNQKSENCEESLVCDEEELENRK 545

  Fly  1002 RTNP----------------MKPILH---TDLEID---FYN-------GCYIQPNLEIMQNDFNN 1037
            ||:.                :|.||.   ..||.|   |||       ..:::||    :.||:
Mouse   546 RTSSEAMLSQYNQPSKFGTLLKRILSDSGLQLESDQERFYNKFFEFPTNLFMEPN----RLDFS- 605

  Fly  1038 AVLCCTEINYFVSTWGKQAKT--QERRDRRVTV-----------DENKYERSYFRYVMEHK---- 1085
                 |:....::|..|...|  ...:|.|:::           :|.| .:|..:|..:.:
Mouse   606 -----TQFQNMIATIEKYVTTIIPLHQDPRLSILVDLVSVPDLSNETK-TKSVVKYKKQTRWPDF 664

  Fly  1086 ----DVIRAVQNLANGLLSYKSDMEEFQRDMFEKY-KYLWAEDREDIINSFV--LTNPLTVDIRD 1143
                |.....||....||:...:......|...:: ||.:..::..::.:.:  :||..:::.:.
Mouse   665 YILFDTDTDYQNKIVTLLTIIGNSVGLVSDYSCRFLKYCYIVEKAKVMTTKLPFMTNLTSIEFKR 729

  Fly  1144 MFLHYDNISLKIETMSAKRIIGPIEVRMG--------------STIEKLVSES---------KKW 1185
            :...:.:...:|.||:       ||:|:|              ..::.::..|         :|.
Mouse   730 IIHKFRSYLKQIVTMT-------IEIRIGIFYVNSLDYQLACLPYVDGIIQMSYNLLQCTIEEKS 787

  Fly  1186 KVLLGHLLSVQYKKQLD----EMIEFITEQNNILDKPINDLDDVRQAMVVLEKVRDNYIEMDVSL 1246
            ..||..|.|:.:  |||    |:.||:        :.:|.|||:..::..:||          ..
Mouse   788 ANLLETLDSLLH--QLDTEPVELEEFV--------EHLNFLDDIFSSLTEIEK----------DF 832

  Fly  1247 QLITDTYSLFSQFYIYVPQEDYDKVEGLQVLFNKMLENAKKVSDRISEM-EEPLLRELNDGIATF 1310
            ..|::.||:...:.|.|.:|   ::...:::|.|.  |..|.|.:...| .|..|.:..:|:..:
Mouse   833 CTISELYSIVRHYQINVSEE---QIAIYKIIFMKF--NHLKTSMKFVAMNRETSLTKFKNGLEAY 892

  Fly  1311 VQEF-YDF-NLDFDLNGPMVEGISA--KEASDRVFLFQNRFDELWRKFEMYSSGEKLFGLPITDY 1371
            :... .|. ||...:..|::...|.  .:|.:.|...:...:.|..|.:.||:.:..:
Mouse   893 IVSLRVDVSNLKDKIRTPLLLAASTPIPKAKEIVQSLEAEAESLTLKVKTYSNYQNYY------- 950

  Fly  1372 PLLHQRKREFNYLNRLYSLYIQVLKTITDY-------------------YEMPWADVNIEKISAE 1417
               .|.....|.:|.....:| ||..|::.                   |...|.:..::.|..:
Mouse   951 ---DQAYFRMNAINTNEMSHI-VLSEISEIECDLMLRKLLWEAQEEWGKYFWEWRNCTLQSIDID 1011

  Fly  1418 L-----SDFQLRCRKLPKGMQSWPAFIDLKTKIDDFNETCPLLELMTNKAMKERHWIRLNALFNT 1477
            |     |.:......|.||:........||..:.||.:..|::..:.|..:|.|||..|..:...
Mouse  1012 LVKNNVSKWLHIIIVLEKGLPKNDMVPLLKQSVLDFRQELPIITALGNACLKARHWETLQGITGR 1076

  Fly  1478 DFDPTNPKFTLGKLLEAPILKYKEDVEDICVGASKELDIEAKLKQIVSDWSLVSLQLGQFKNRGD 1542
            . ...|...::.|||...:..|:..:.:|.:.|:.|..:|..|.:|:..|:...|.|......|.
Mouse  1077 S-TSLNKNLSIEKLLALKLFPYERKINEISISATNEAALEKMLFKIIDLWNTTPLHLVPHLTEGR 1140

  Fly  1543 LVLKGGETLEIISSLEDSLMIMNSLASNRYNAPFKKDIQLWLSKLVNTGDILEKWLMVQNLWIYL 1607
            .:|....|.::|:.||||..|:.|:..:.|..|.|:.:..|...|......:::|:..|..|:.|
Mouse  1141 SILIISSTDDLITQLEDSQAILASIKGSSYLRPIKQLVIKWNQNLTLFSQTIDEWVTCQRTWLSL 1205

  Fly  1608 EAVFVGGDISKQLPMEAKRFTNIDKSYVKIMMRAREIPNAVDCCTGDESLATNLTWLL----DQL 1668
            |.:|...:|.|||..|||.|:.:...:.:||.|.....||:..     :::|.:..:|    ..|
Mouse  1206 EPIFQSLEIQKQLAAEAKLFSQVLVMWKEIMSRVLNKLNALHI-----TISTGILGVLKSCNSHL 1265

  Fly  1669 ETCQKSLTGYLESKRLVFPRFFFVSDPVLLEILGQASDPTSIQPHLLSIFDAIATVDFQEKSI-- 1731
            |:.:|||..|||.||:.||||||:|:..||:||..:.:|.|:||||:..|:.|..:...::.:
Mouse  1266 ESIKKSLEEYLELKRMSFPRFFFLSNDELLDILANSKNPESVQPHLVKCFENIRRILLWKQDVGP 1330

  Fly  1732 DIIESMNSMNREKVKFENTVQCLGSVELWLGRLLKEMQDTIRTILAQMSVSLNDPEFN-FAEEFP 1795
            ..::.:.|...|.:.....::...|||.|:..:.|.|.|.::..:.|   .:.|.::: |::...
Mouse  1331 PSVKMLISAEGEGLVMPKKIRVRASVEQWMVNVEKSMFDVLKKFIIQ---GIEDWKYHTFSDWVM 1392

  Fly  1796 SFCGQAGVVGVQLLWTKDSEYALRKCRTDKTIMKRTNNKFLV-----LLNFFIDLTVKDLTSLDR 1855
            |..||..:..:|:::..|       |.  |..|.....:.|.     ||....|:.|....:...
Mouse  1393 SHPGQVVITVIQIMFYND-------CL--KGFMSYNPREILEAVQARLLRHLEDIAVLVTLNTSN 1448

  Fly  1856 IRFETMVT----IHVHQRDIFDDLCTLRIKSAGDFEWQKQARFYYNEDNDDVIVGITDVNFVYQN 1916
            .|.:||:.    |.||.|||..|:...:|.|..||||.:..|:.:|.......|...:.:|||..
Mouse  1449 QRTKTMLAATLIICVHCRDIMSDVLVKKIFSIQDFEWTRHLRYKWNGKQKLCYVLQANTSFVYGY 1513

  Fly  1917 EYLGVTERLAITPLTDRCYITLAQAVGMCMGGAPAGPAGTGKTETTKDMGRALGKLVVVFNCSDQ 1981
            ||||...||.|||||:||:::|::|:...:||..|||||||||||.||:.::.||..|||||.:.
Mouse  1514 EYLGCAPRLVITPLTERCWLSLSEALYFNLGGCTAGPAGTGKTETVKDLAKSFGKHCVVFNCFED 1578

  Fly  1982 MDFRGLGRIYKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKEKRSTFIFLDGDIVSLN 2046
            :|::.:|:::.||.|||:|.||||||||.:.||||.|.||..:..|:......|: |||..:.:|
Mouse  1579 LDYKIIGKLFFGLVQSGAWCCFDEFNRISIEVLSVIASQILAIKIAKSSYSVRFV-LDGREIRIN 1642

  Fly  2047 PEFGIFITMNPGYAGRQELPENLKIMFRTVAMMVPDRQIIIRVKMASCGFKENVVLSRKMYTLYK 2111
            ....:.||:|||..||.|:|:|||.:||.|::|||..::|..|.:.|.|||.:..||.|:..||.
Mouse  1643 MSCAVLITINPGTTGRVEIPDNLKYLFRLVSIMVPHYKMITEVILFSYGFKSSRSLSGKIVHLYD 1707

  Fly  2112 LCEEQLSKQVHYDFGLRNILSVLRTLGSQKR---------SNPNDTEETIVM-RVLRDMNVSKLI 2166
            |.::|||||.|||||||.:.:||  :.::|:         .:.::.:|:::: ..:|:.::|||:
Mouse  1708 LADKQLSKQEHYDFGLRTLKTVL--IMTEKKILEHKCGRGEHLSELDESLILIEAIREASLSKLL 1770

  Fly  2167 DEDEGLFVSLVDDMFPGIKLTTNVYKDLQKAIIKVCDELGYVNNPEWNLKVVQLYETSLVRHGLM 2231
            .||...|..:::|:||.|.::...:..|:|||....::||:.:.|....|::|.|:...|..|::
Mouse  1771 PEDVLPFEKIIEDVFPRITVSKINHLTLEKAISTATEQLGFQHWPSQKEKIIQFYQQLQVCVGVI 1835

  Fly  2232 LMGPTGSGKTSCTVCMLRCFTEMGRTH----KEMR----------------MNPKAITAPQMFGR 2276
            |:||||.|||:....:.:....:..|.    ||.:                :|||.||..:::|:
Mouse  1836 LVGPTGGGKTTVRKILEKALVTLPVTSAMLMKERQSDSKSTGKKGKVDVCVLNPKCITLSELYGQ 1900

  Fly  2277 LDVATNDWTDGI--------------------------------------FSTL----------- 2292
            |::.|.:|.||:                                      |||:
Mouse  1901 LNINTMEWNDGLLSAAIRNYVHMNTADYSKIDNDFEMSGITDLSNIFQVGFSTIADMDNNIFMGE 1965

  Fly  2293 WRRSLKVPQHQNC---WIVLDGPVDAVWIENLNSVLDDNKTLTLANGDRIKMADNSKLVFEPDNV 2354
            ..:|.|.|:..:.   |||||||:|::||||||:|||:.:||.|||.:||.:.:..::|||.|::
Mouse  1966 LEKSFKTPEIHDFDWQWIVLDGPIDSLWIENLNTVLDETRTLCLANSERISLTNKIRIVFEADSL 2030

  Fly  2355 DNASPATVSRVGMVFTSSSVLSWKIYMEAWLLKQGED-SEVFRRCYDVLYDDAHV----FLQSR- 2413
            .:|:|:.::|..||:.....|.|:.||::||||..:. |:...:|.:::.:.:..    ||:..
Mouse  2031 FDATPSVITRCAMVYMDPVDLGWEPYMKSWLLKSSKSISQQGIQCLEMMINRSVTKGMKFLKKHR 2095

  Fly  2414 ------------LLAKMRILEAIYIRQMLDIMDG------------------------------- 2435
                        ::...|||:|.:  :.:.|..|
Mouse  2096 KFLPYPIQDVTVVITLCRILDAFF--EFMHIKQGTPKSHEAMDSESPTETKVKVKFKEETSHHKD 2158

  Fly  2436 ----LLLDLPLRTEKALERIFLFSLMWSLGAVLELSE--------REKLEEFLLKHV-------- 2480
                .|...|.:....:::||:|:..|:.|.:|:..:        |:..|...|..|
Mouse  2159 EGSWFLERNPEKLPMMIQKIFVFAFTWAFGGILKREDQHEEDILFRKSFEHDSLAEVNYNFDIFV 2223

  Fly  2481 -----------SKLRWPKRGVNETIFEYYVD-DNGNWQHWSTRV--------------EEFRYPE 2519
                       :.:..|  |...::|.|:|| ....:..||..|              .:|:...
Mouse  2224 REVFEDDSERDTGISLP--GSERSVFGYFVDVQQCEFMPWSDLVPTAHTLIQKETSLLTDFQGSS 2286

  Fly  2520 DEI---PEFSSIL--VPNVDNVRTAFLLHNIAKQLKQVLLIGEQGTAKTVMIKAYMGHYDPE--- 2576
            :.:   .|:...:  :...|.:..:||:....:....|||.|:.|..|:|.|...:...:..
Mouse  2287 ENVLRMNEYGECVNYMATRDTICLSFLMSLFLRNSYPVLLTGDCGVGKSVAINKMLEKLEGRGTL 2351

  Fly  2577 ------------VH-------------------------------------------------IF 2580
                        :|                                                 |.
Mouse  2352 NIKYGSILGKVLLHNDIKRSSLRQNINILIGDPTKIIGAGLEQSAKKEEAKANDSTVINDKGIIV 2416

  Fly  2581 KSFNFSSATTPNMYQRIIESYVEKRQGTTYGPPNQRAMTIFIDDINMPVINEWGDQITNEIVRQM 2645
            .:.||:|..|....:.::...:.:|.....|.|....:.:||||:|||:::..|.|...|::||:
Mouse  2417 STINFTSTMTAAKTKELLLRKLVRRTKDILGAPKNNRIVVFIDDLNMPIVDACGTQPPLELIRQL 2481

  Fly  2646 IEQRGFYSLERPGDFSTIMDIQMLSAMIHPGGGRNDIPNRLKRHLCIFNCTLPSNNSMDQIFKSI 2710
            ::..|.|..|| ..:.:|.|:.:::|......|: :|..||.:|........|..:::..:|::.
Mouse  2482 LDMGGVYDTER-NMWKSIQDLSLIAAYTSSVSGK-EISPRLLKHFSTLVLPHPPQSALCTVFQAH 2544

  Fly  2711 GAGYFSPDRLGDEVVEVIPLLVPLTRIFWQNVKAKMLPTPANFHYVFNLRDLSRIWEGILKVKHE 2775
            ...|||.:...:||.:....:|..:...:..|..|:||||...||:||.||:.::..|:::....
Mouse  2545 LGMYFSINNFVNEVQKCRDEIVHCSLAIYYEVCKKLLPTPTKCHYIFNPRDIFKLLLGLMQADKN 2609

  Fly  2776 ECKSVDQILKLWCHECTRVISDRFTAEKDKIWFSSKMISDAELNIKEFM--EFYPEEPTYWVDFL 2838
            ...|.:....|..||.:||..||.|.:.:|..|...:.::.:.:::.:.  |....:|..:|||
Mouse  2610 IINSKEMAALLLVHEASRVFHDRLTDQSEKSLFYQILSTELQNHLQIYWSHERLMNKPVLFVDF- 2673

  Fly  2839 RDAPEGQEEEDEEMSFEPP---KIYEEIPSFDFVRSKVLVFMSQFNEYIRGYNMDL----VFFMD 2896
                         |....|   ::|:...::    :::|..:::|.:.:...::::    |||.:
Mouse  2674 -------------MDINKPHRKRVYQNTDNY----NELLSILTKFQQKLSSSSLEMSHSVVFFKE 2721

  Fly  2897 ALKHLMIVSRIISNPRGNALLVGVGGSGKQSLTRLSSFIAGYKFFQMTLTRSYNTGNLTEDLKFL 2961
            |:.|:...:|.:.....:.||:|:.|.||::...::.::|.||..::.::.:|......|..|.:
Mouse  2722 AIDHITRTTRALRQSGSHMLLLGIDGCGKETYATIACYLAEYKVCKVPISHNYAISEFKEMFKKV 2786

  Fly  2962 YRTAGLDGNGMTFIFTANEIKEESFLEFINNILSSGEIANLFAKDELDEM------YSELIPVMK 3020
            :...||:......:.|..:.:..||||.:|.|:::|:|:|:|..:|||.:      ::|.:..::
Mouse  2787 FIQTGLEETPTVVMVTNLQEEHVSFLEDLNYIINAGKISNMFENEELDSIVMRVGTFAEQLTCIE 2851

  Fly  3021 KHQPRRPATQDNLYDFFISRARYNLHIALCFSPVGEKFRMRSLKFPGLISGCVIDWFQKWPEDAR 3085
            ..:        .|...|..|...||||.: .|..|..||.....:|.:||.|.|||||:||::|.
Mouse  2852 DRK--------YLLSLFQRRVSKNLHICM-ISATGPNFRHNCRVYPSMISSCTIDWFQRWPDEAL 2907

  Fly  3086 IAVSRHYLTDYQIVCSEKVKDQVIDIMSW------IHESVQETCLSYYDRFRRVTFVTPKSLISF 3144
            :.|:..||.:     ..||:|:...|..:      ||:|:::....|::...:..::||.....|
Mouse  2908 LVVASSYLKE-----KLKVEDKEDKIREFAPTCVEIHKSMKDLSAKYFEETGKHYYITPSCYFKF 2967

  Fly  3145 LESYKLLYKDKQDHIVIMSERMSSGLDKLDEAGASVAILKKDLIEMNKVIALASEEAEDVLATVE 3209
            ||::....:.:|:.:.....|...||.|:.||...|..::::|:.:...|...::|.|.::   |
Mouse  2968 LETFTHSLRIRQEEMQTKRNRFYMGLSKILEATVLVTDMQEELLVIGPQIEQKAKEKEILM---E 3029

  Fly  3210 QSKAAAEIV-KVEVAEKKGQAEVLVKNISAVKHVAEA---KLEKALPALEEAEAALKTIKAADIA 3270
            :.:..::|| ||::..|:.: |::.:.:..|:..|:.   :|:..||:|::|..||..:..:||:
Mouse  3030 KLRKDSQIVEKVQMLVKQDE-EIVAEQVKIVEEYAQKTSNELKNVLPSLDKAIVALNALDKSDIS 3093

  Fly  3271 TVRKLGKPPYLITLIMDCVCILFRRKVKPIRPDTEKAFIQSSWDESLKVMSDTSFLRKIVEYPTD 3335
            .:|...:||||:..:|:.||||..:|              .:|..:..::||||||::::....|
Mouse  3094 ELRVYTRPPYLVLTVMNAVCILLEKK--------------PNWATAKLLLSDTSFLKRLINIDKD 3144

  Fly  3336 LINAEMVDMMVPYFQYPQYTFEAAKVACGNVA--GLLSWTMAMSKYFEVNKEVLPLKANLAVQEA 3398
            .|..::...:......|.  |...|:|..:||  .:..|.:|::.|.||.|.|.|.:|.:|..:.
Mouse  3145 SIPDKVFLRLKKILNLPD--FNPNKIAMVSVACCSMCQWVIALNNYHEVQKVVRPKQAQVAEAQN 3207

  Fly  3399 KYQKASSDLQEAEELLQQKENELAEVQQTLEDAVSKKDAVLDEAKKCQDKMDAATALIGGLAGEK 3463
            ..|.|...|.|.:..||..|:.|..:..:..|.|::|..:....|....::..|:.|:..|..||
Mouse  3208 VLQIAKQRLLEKQRGLQLIEDHLQFLHTSYRDIVTEKHQLASRKKLATKRLQCASVLLTVLEDEK 3272

  Fly  3464 IRWTEQIASFKSETDRLVGDVILLTAFLSYTGPFNQEFRSDLQSIWTKQIIEKMIPISANVNIIE 3528
            |||.|.|.....:...:.||..|.:|.|:|.|....|||..:...|........|.:|.|.::|:
Mouse  3273 IRWQETINEIDCKLKGVCGDTFLSSACLAYIGVLTPEFRELVIQKWKDFCTRAEIILSPNFSLID 3337

  Fly  3529 SLTDRSQIGEWNIQGLPTDELSIQNGIISTKAMRFPLLIDPQSQGKVWIKNKEKQNKVIVTTLNH 3593
            .:.::::|..|:.||||..:...:|.|:..:..::||:|||..|...||:..|......::..:.
Mouse  3338 VMAEKNEIRRWHNQGLPLGQHLAENAILMKRTKQWPLVIDPHKQALHWIRQMEGPRLQEISAQDS 3402

  Fly  3594 KYFRNHLEDSVSMGIPIIIEDVAEELDPCLDNLLDRNLLKVGTQYKIKIGDKEVDWNPAFRCYIT 3658
            .|.:. |..::..|.|:::::|.|...|.|..:|.:::.:...||.|||.|.|:::|..||.|::
Mouse  3403 NYTKK-LVIAMQAGDPVLLQNVPETFPPNLRAMLKKDVCQKRGQYYIKIDDTEIEFNKNFRLYLS 3466

  Fly  3659 TKLPNPAYTPEIFARTSIIDFTVTMRGLEDQLLGRVILAERKELEDERVQLVETVTGNMKKMKEL 3723
            |:|.||.:.|.::...:||:||||.:||:|:||..|:..|...||::|.||:|:::.:...::||
Mouse  3467 TELENPNFFPSVYNFVTIINFTVTFQGLQDELLSTVVSHEVPHLENQRAQLLESISLDAITLEEL 3531

  Fly  3724 EANLLQKLSTTKGSLLDDVTVIEVLNTSKNTAIEVKEKIEIAKVTEAKINAAREEYRVVATRGSV 3788
            |...|..|...:||:|||..::|.|...|.|:.|:.::|:..:..|:||.|.|:.|..:||||::
Mouse  3532 EDKTLTLLQKAEGSVLDDEEIVETLRKCKMTSNEISKRIKETEKAESKIQATRKNYLPIATRGAL 3596

  Fly  3789 LYFLVCSMARVNNMYQTSL-------VQFL------ERFD-------------ASMYNSSKTHIT 3827
            |||:|..::.|..|||.||       |.|.      |:.|             .|:.:|.:.::.
Mouse  3597 LYFVVAGLSHVEKMYQFSLEWLRGVFVSFTVSKTKEEKHDWKTDETSQEKADEVSLSSSEQENLE 3661

  Fly  3828 QKR------IKRIINYLTFEIYRYKSRGLYEKDKFLFVLLMALSIDR----------QLELITFD 3876
            .:|      ||..|..||..:::..|..|:.:.|..|...:..:|.|          .:..:..:
Mouse  3662 SERIPLAENIKNAIETLTRNVFKVVSSALFNEHKLCFSFALCTTIMRGNSSDTLMADDIGFLPEE 3726

  Fly  3877 EFQVFIKGGAALNLNDCPPVP-------------FRWTTDETWLNLVQLTN-LTPFVNILSKVSG 3927
            |:.:|:.....:|:.:....|             .:|..|..|.....::| :.||..:.:.:..
Mouse  3727 EWNIFLYTSILINIKNILSKPRLNSIFEIRRNGHLQWVPDLRWRQCQYISNQMEPFSLLCTSLLS 3791

  Fly  3928 NERAWFTW-------------YKKDAP----------ENEIIPDGYNSLDP----------FRKM 3959
            ||:.|..:             :..|||          |.|::.:....|||          |:::
Mouse  3792 NEQQWNAFKDAMAVYSLMSRPFFSDAPLPQKKPRSAKEAELLDESDEMLDPVTFPWEKLTQFQRL 3856

  Fly  3960 LLVRSWCMDRTISQCRKYIANSLGDRFAEPVVLNFEELLLESRELMPMICFLSLGSDPSSNIELL 4024
            :|::....||..:..:|:|...:|..:.....:|.:|...||....|:|...|.|.|.::.:...
Mouse  3857 ILIKILRPDRLENSIKKFITEKMGGEYIPDTTVNLKESFSESTAQTPLILTHSYGIDLNNLLLRF 3921

  Fly  4025 A---KKNELKCHPISMGQGQEIHARKLILSCLEDG-GWVLLQNCHLGLEYMVELTVQILELERQG 4085
            |   |....|...||:|..||..|.::|...:... .||.||||||...:|..||..|...  ..
Mouse  3922 AEEFKGTTPKVTMISLGPDQENKAEEIIFKAVRKAHQWVFLQNCHLAESFMPRLTAIIDSF--SS 3984

  Fly  4086 KDAAVNPNFRIWITTEPHPKFPITLLQMCLKYTNEPPAGIRAGLKRTY-----TNLSQDFLDYSQ 4145
            .|..::|:||:|::::....||||:||..:|...|||.|:::.|.:.:     ..::::..:...
Mouse  3985 PDMVLDPDFRLWLSSKASGFFPITILQKSVKIAVEPPQGLKSNLLQMFGYGGSGEVTEEMFEKPD 4049

  Fly  4146 -SPFYLPLVYSISFLHTVVQERRKFGPLGWNIPYEFNSSDWYASCLFVQNHLDDIEQGKGISWVT 4209
             .|::..:::||.....|:.||:.:|.|||||||.|:|||...|...:.|.|....:   :.|..
Mouse  4050 CGPWWKKILFSICLFSAVLIERKAYGTLGWNIPYRFSSSDLEVSLKVLGNVLSGRSE---VPWKE 4111

  Fly  4210 VRYMLGEVQYGGRVTDDYDKRLLNT-FTRVWFHDTLFEDCFQFFKGYKVYSFKEQEAY-----LA 4268
            |.|::.||.:||||.|::|.|.|.| |.:....:.|.:|          |||...|.|     .|
Mouse  4112 VNYLISEVTFGGRVVDEWDMRCLKTLFDKFCNPEMLKDD----------YSFSSNEMYQPVPSSA 4166

  Fly  4269 AIDDMANV-------DPPQVYGFHSNAEITYQTNTMRNILDEIMSIQPKESSA----GTGESRED 4322
            ::.|..|:       |.|::.|.|..|..|......:..::.::.:|||::..    ...:|.:.
Mouse  4167 SLKDCINIIQSFPDDDSPEILGIHPEATHTGSEIKAQKYIENLIYMQPKDAPGYLMIKPMQSNDS 4231

  Fly  4323 RVARQVKEMLSKTPLAFDLFDVKQHLIAMGATSSM------------NI-------------FLR 4362
            .|...:.:::|:.||..:..||.:.  .:.:|.|.            ||             ||:
Mouse  4232 VVMEVLSDIMSQLPLTVESEDVSEP--GLQSTFSFIVSSPIWERLHENIQGYDPLIHSVLIPFLK 4294

  Fly  4363 QEIDRMQRIIILVRSIFKDLLLAVEGTIIMSENLRDALDNIFNARVPTVFKRGSWVS-SSLGFWF 4426
            :||:|..:::.::....|.|.||::|..|::.:|.:..|:...||||.::::.::.| ..|..|.
Mouse  4295 KEIERFNKLLSVIHKSLKSLQLAIKGESILTPDLEETYDSFLRARVPMLWQKNAYKSCKPLSIWV 4359

  Fly  4427 TELLERHTQFYNWC--------------------FGAR---------------PVVFWMSGFFNP 4456
            :.|::|...|..|.                    .|.:               |..:|:|.||:|
Mouse  4360 SNLIQRVNFFNTWAKVAYTAIHHRYMLFITTWRQLGQKSRHPTDFKTEITDGFPARYWLSAFFSP 4424

  Fly  4457 QGFLTAMRQEVARAHQGWALD------------QVTMHNDVLKVGPEECK-----------KPPK 4498
            |.|||||.|:..|| ||.::|            .||..:|:.|:..:...           ..||
Mouse  4425 QAFLTAMLQDYGRA-QGISMDTLTFTHKVIYNISVTQEDDISKLLQKRLNIVRRAFQQHQDHSPK 4488

  Fly  4499 EGVFVYGLFVDGAGWDKRTSRLVEATNKVLFTLMPVIHIYAIFST----------AAKNSKLYTC 4553
             ||:::|||::||.||.....|.::....|....|.|.......|          .|.:.:.:.|
Mouse  4489 -GVYIFGLFMEGARWDPEQEVLEDSLPSQLCCEFPDILFLPTKITEPSASQDSDQTASDLQTFEC 4552

  Fly  4554 PVYKKINRT------DLNYICALWLQSNKHPDHWTLRGVALLCD 4591
            |||....|:      ....:.::.|.:.|.|.||....|||||:
Mouse  4553 PVYYTPERSRNMIGLPTTVLTSVHLPTKKPPSHWITMQVALLCE 4596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kl-3	NP_001104482.3	DHC_N1	266..800	CDD:285571	51/283 (18%)
		DHC_N2	1378..1778	CDD:285579	113/429 (26%)
		P-loop_NTPase	1914..2145	CDD:304359	112/239 (47%)
		P-loop_NTPase	2229..2364	CDD:304359	59/206 (29%)
		P-loop_NTPase	2521..2790	CDD:304359	68/337 (20%)
		P-loop_NTPase	2889..3151	CDD:304359	74/277 (27%)
		MT	3164..3506	CDD:289543	97/347 (28%)
		AAA_9	3538..3754	CDD:289547	73/215 (34%)
		Dynein_heavy	3900..4582	CDD:281078	211/842 (25%)
Dnah14	NP_001363968.1	DUF4168	328..391	CDD:379360	13/69 (19%)
		DHC_N2	973..1378	CDD:369852	109/413 (26%)
		DYN1	1202..4193	CDD:227570	836/3084 (27%)
		AAA_6	1511..1845	CDD:372306	142/336 (42%)
		AAA_9	3348..3563	CDD:372311	73/215 (34%)
		Dynein_C	4202..4595	CDD:375627	91/396 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100025
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900