Protein Alignment Myo81F and myo1cb

DIOPT Version :10

• Sequence 1: NP_001303492.1
• Gene: Myo81F / 26067052
• FlyBaseID: FBgn0267431
• Length: 2082
• Species: Drosophila melanogaster
• Sequence 2: XP_073779253.1
• Gene: myo1cb / 566459
• ZFINID: ZDB-GENE-090429-3
• Length: 1069
• Species: Danio rerio
• Alignment Length: 1130
• Identity: 327/1130 - (28%)
• Similarity: 531/1130 - (46%)
• Gaps: 192/1130 - (16%)

  Fly     7 RVGFADMTEM-SEIDEIGINQNLNVRYNSDIIYTYTGSILLAVNPYKTINIFNKQTISEYHTCKL 70
            |||..|...: :...|:...:||..|:..::||||.||:|::|||||.:.|:.||.:..|.....
Zfish    52 RVGVQDFVLLENHTSEVAFIENLRKRFKENLIYTYIGSVLVSVNPYKDLEIYTKQHMERYRGVNF 116

  Fly    71 GDLSPHVFAVAEAAYTSIVDDNINQACVISGESGAGKTESTKFILQY---LCTITSNVSSWVQQQ 132
            .::|||::|||:.||.|:..:..:|..:|||||||||||::|.:|||   .|..:.:|.: |:.:
Zfish   117 YEVSPHIYAVADNAYRSMRTERRDQCILISGESGAGKTEASKKVLQYYAVTCPASDHVQT-VKDR 180

  Fly   133 ILEANTILEAFGNAKTTRNDNSSRFGKFMQVCFDDNNCIKGCVILDYLLEQSRITFQSEGERNYH 197
            :|::|.:|||||||||.||||||||||:|.:.||......|..||:||||:||:..||.||||:|
Zfish   181 LLQSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILNYLLEKSRVVHQSNGERNFH 245

  Fly   198 IMYQLVAQGQ----KNIGIANTFHLRPAEFYKYLNTSNSEKINMNLESKKFDAVTMAFTVLQIPQ 258
            |.|||:..|:    :.:|:.     |.|:.|:||...|..|::...:...:..|..|.:|:....
Zfish   246 IFYQLIEGGEDDLLRRLGLE-----RNAQQYQYLVKGNCPKVSSINDRNDWKTVRKALSVIGFTD 305

  Fly   259 FVIDGVFKVISSILWLGNIEFIDVDGEVTDLTRSDQEAISIISMLLGLSRCDFKKVLLIRQINVR 323
            ..::.:..:|:|:|.|||:::...|.....:|...|  |..::.|||:.....|:.|..::|..:
Zfish   306 DEVEELLNIIASVLHLGNVQYGGEDSGSAYITTDTQ--IKYLARLLGVDGTVLKEALTHKKIIAK 368

  Fly   324 GNITEIPLKIKEALENRHALAKALYSKMFTWLVSKINNC-----TNPGQDDAKFLGVLDIFGFEN 383
            |.....||..::|...|.||:||:|.:.|:|||:|||:.     .:....:|..:|:|||:|||.
Zfish   369 GEELMSPLNQEQAASARDALSKAIYGRTFSWLVNKINDSLAFKDESFSSKNASVIGLLDIYGFEV 433

  Fly   384 FSHNSFEQLCINYTNEKLHKFFNHYVFALEQSIYEHEGIYFNHVEFTDNTPCLEILEKPPRCVFK 448
            |.:|||||.||||.||||.:.|.......||..||.|||.:..|::.:|....:::|:..:.:..
Zfish   434 FQNNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGITWEPVQYFNNKIICDLVEEKFKGIIS 498

  Fly   449 LLTEQCHMP-QGSDLAFLSNMHTEFESHPNYI-----KGSDRR-HWETEFGIKHYAGLVIYAVGG 506
            :|.|:|..| ..||:.||..:......|.:::     .|..|: ....||.:.||||.|.|.|.|
Zfish   499 ILDEECLRPGDASDITFLEKLENTVGGHAHFLTHKLADGKTRKVMGREEFRLIHYAGEVNYNVKG 563

  Fly   507 FVEKNRDVQQDVMFEYMSYSKDVFIKDLSTYQDIQFINSSYPR---GSSKSKCTVSDNFRNQLQS 568
            |::||    .|::|..        :|.:....:.:.:|..:.|   ...|...|.:..|:|.|..
Zfish   564 FLDKN----NDLLFRN--------LKQVMCMSENKILNQCFDREELSDKKRPETAATQFKNSLAK 616

  Fly   569 LIDVLQNTKPWYVRCIKPNLQKRPNNYNSSLVLDQLKYLGVVDIIRIRREGFPIHLSHKDFIVRY 633
            |:::|.:.:|.||||||||..|:...::..|:..|:||||:::.:|:||.||.....::.|:.||
Zfish   617 LMEILMSKEPSYVRCIKPNDAKQAGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRRYETFLQRY 681

  Fly   634 KCLIKNKSFEYPQKY---LTNILEKNGMPTTEWQIGKSKIFLR-----NAAYELLETNRKDTLYK 690
            |.|..:....:..:.   ::.:::..|....|:::|::|||:|     .|..:.||. ||.:|
Zfish   682 KSLCPDTWPNWDGRQVDGVSTLVKHLGYKPEEYKLGRTKIFIRFPKTLFATEDALEV-RKHSL-- 743

  Fly   691 NAVIIQKNWKKYYIQKSFLRNKQAVLRIQHAYRGWRLRIRFMRMRRSAIVIQSRLRGVFAREVAA 755
             |..:|.:||                       |:..:.::.:||.||:.||:..||:.||..|.
Zfish   744 -ATQLQSSWK-----------------------GYSQKTKYQKMRHSAVWIQAWWRGILARRAAK 784

  Fly   756 ALREMKRVDEELKKRDGIYEQLTSITTKTLADCERS------IQEELSVLAHISDNIRASAKPLS 814
            ..||         ..|.|...:.....:....|..:      ::....:..|     |...|.:.
Zfish   785 RRRE---------AADTIRRFIKGFIYRHQPRCPENEYFLDYVRYSFLMNLH-----RCQPKTVL 835

  Fly   815 DKNDSDSNTARSSIKQNTVNL--DNMFDFLCESKGAFENALIKEINDNWNNLVKNLDEEIGLCIH 877
            ||:......|.....|:...|  .||....|           |.||..|.:   .:::::
Zfish   836 DKSWPTPPPALVEASQHLRKLCMQNMVRKYC-----------KNINPEWKH---QMEQKV----- 881

  Fly   878 TEDSFDSQKTGKLFTTKTVRTLPEPTVPPPPPPVSISANLNSEPI-------------------- 922
                    ...|:|..|      :...|...|.:.::..||.|.|
Zfish   882 --------VASKIFKDK------KDNYPQSVPKLFVNTRLNGEDINPKVLQALGNEKMKYAVPVI 932

  Fly   923 ------YEAIN--LYKLTTTKEIKKEKYM--LLDYKSIKDNSKKPSTSSVFVKYQIDERENRRKQ 977
                  |:|.|  |..::.:..|.:|..:  .:||.|:|..|....:..:|| :.:...:|::|.
Zfish   933 KYDRKGYKARNRQLLLMSDSAVIVEEGKLKQRIDYNSLKGISVSSLSDGMFV-FHVASEDNKQKG 996

  Fly   978 RV----EKKIHELTLIDIHKDIHIDNSFYNILEFAENYFNTHDLSSDCNFISTPTQKGKSS--DK 1036
            .|    |..|..||.:.|..|                  ...|::.:...|.....:||..  |.
Zfish   997 DVVLQNEHVIETLTKVAICAD------------------KMDDININQGSIKFDVAQGKEGIIDF 1043

  Fly  1037 TAKHEMTMFSKSDKIPTSHIHMYDP 1061
            ||..|:.:.    |....|:.:..|
Zfish  1044 TAGSELLIV----KAKNGHLSVTAP 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo81F	NP_001303492.1	Motor_domain	23..673	CDD:473979	237/674 (35%)
		MyTH4	1091..1194	CDD:459939
		FERM_F1_DdMyo7_like	1198..1299	CDD:340728
		B41	1202..1419	CDD:214604
		PH-like	1415..1523	CDD:473070
		MyTH4	1664..1771	CDD:459939
		FERM_F1_DdMyo7_like	1775..1880	CDD:340728
		B41	1781..1992	CDD:214604
		PH-like	1988..2076	CDD:473070
myo1cb	XP_073779253.1	None