Protein Alignment Myo81F and Myo3b

DIOPT Version :10

• Sequence 1: NP_001303492.1
• Gene: Myo81F / 26067052
• FlyBaseID: FBgn0267431
• Length: 2082
• Species: Drosophila melanogaster
• Sequence 2: NP_796350.2
• Gene: Myo3b / 329421
• MGIID: 2448580
• Length: 1333
• Species: Mus musculus
• Alignment Length: 790
• Identity: 251/790 - (31%)
• Similarity: 418/790 - (52%)
• Gaps: 85/790 - (10%)

  Fly    12 DMTEMSEIDEIGINQNLNVRYNSDIIYTYTGSILLAVNPYKTINIFNKQTISEYHTCKLGDLSPH 76
            |:..:..:||..|...|..||...:||||.|.||:|:||::.::|::.|....||..|.....||
Mouse   363 DLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRSSNPPH 427

  Fly    77 VFAVAEAAYTSIVDDNINQACVISGESGAGKTESTKFILQYLCTITSNVSSWVQQQILEANTILE 141
            :||.|:.||..:|..:.:|..|||||||:|||||...|:|:|..:....:..::|:||:.|:::|
Mouse   428 IFASADNAYQCLVTFSKDQCIVISGESGSGKTESAHLIVQHLTFLGKADNQTLRQKILQVNSLVE 492

  Fly   142 AFGNAKTTRNDNSSRFGKFMQVCFDDNNCIKGCVILDYLLEQSRITFQSEGERNYHIMYQLVA-- 204
            |||||:|..|||||||||::::.|.....:.|..|.:||||:||:..|:.||:|:||.|.:.|
Mouse   493 AFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARISEYLLEKSRVIQQAAGEKNFHIFYYIYAGL 557

  Fly   205 QGQKNIGIANTFHLRPAEFYKYLNTSNSEKINMNLESK-----KFDAVTMAFTVLQIPQFVIDGV 264
            ..||.:.   .|.|...:..:|: ...:|::..::.||     :|:|:...|.::......:..|
Mouse   558 YHQKKLA---EFRLPEEKPPRYI-AGETERVMQDITSKESYRTQFEAIQHCFKIIGFADKEVHSV 618

  Fly   265 FKVISSILWLGNIEFIDVDGE-VTDLTR-SDQEAISIISMLLGLSRCDFKKVLLIRQINVRGNIT 327
            :::::.||.:|:|||..:..: .||.:. .:.||:...:.:|.:|..:.::.|....:..||...
Mouse   619 YRILAGILNIGSIEFAAISSQHQTDKSEVPNPEALENAACVLCISSEELQEALTSHCVVTRGETI 683

  Fly   328 EIPLKIKEALENRHALAKALYSKMFTWLVSKINNCTNPGQ-----DDAKFLGVLDIFGFENFSHN 387
            .....:..|.:.|.|::||||.::|:|:|::||....|.:     :|...:|:|||||||:|..|
Mouse   684 VRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLLQPDKNICSAEDRMNVGILDIFGFEDFQRN 748

  Fly   388 SFEQLCINYTNEKLHKFFNHYVFALEQSIYEHEGIYFNHVEFTDNTPCLEILEKPPRCVFKLLTE 452
            ||||||||..||::..:||.:||||||..|::||:....|::.||.|.|::..:.|..:..||.|
Mouse   749 SFEQLCINIANEQIQYYFNQHVFALEQMEYKNEGVDAVLVQYEDNRPLLDMFLQKPLGLLALLDE 813

  Fly   453 QCHMPQGSDLA----FLSNMHTEFESHPNYIKGSDRRHWETEFGIKHYAGLVIYAVGGFVEKNRD 513
            :...|||:|..    |..|:..:|...|..:        |..|||:||||.|:|...|.:|||||
Mouse   814 ESRFPQGTDQTLVDKFEDNLRCKFFWRPKGV--------ELCFGIQHYAGPVLYDASGVLEKNRD 870

  Fly   514 VQQDVMFEYMSYSKDVFIKDL------------STYQDIQFINSSYP----RGSSK--------- 553
            .....:...:..|::..::.|            .|...|...:.|.|    .|.:|
Mouse   871 TLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRAKITASSRSLPPHFSAGRAKVDTLEVIRH 935

  Fly   554 -------SKCTVSDNFRNQLQSLIDVLQNTKPWYVRCIKPNLQKRPNNYNSSLVLDQLKYLGVVD 611
                   .:.|::..||..|..|:..:...:|.::||||||..::...::...||.||:..|:::
Mouse   936 PEETTNMKRQTMASYFRYSLMDLLSKMVVGQPHFIRCIKPNDDRKALQFSQDRVLAQLRSTGILE 1000

  Fly   612 IIRIRREGFPIHLSHKDFIVRYKCLIKNKSFEYPQKYLTN------ILEKNGMPTTEWQIGKSKI 670
            .:.|||:|:...:..::|:.||..|    :|...|....|      ||||:.:  ..|.:||:|:
Mouse  1001 TVSIRRQGYSHRIFFEEFVKRYYYL----AFRAHQTPPANKESCVAILEKSRL--DHWVLGKTKV 1059

  Fly   671 FLRNAAYELLETNRKDTLYKNAVIIQ---KNW---KKYYIQKSFLRNKQAVLRIQHAYRGW--RL 727
            ||:....|.|....::.:.: .|::|   |.|   ::|...|.  :.::..:.||.|:||:  |.
Mouse  1060 FLKYYHVEQLNLLLREVMGR-VVMLQAYTKGWLGARRYKRAKE--KREKGAITIQSAWRGYDARR 1121

  Fly   728 RIRFMRMRRS 737
            :::....|||
Mouse  1122 KLKQRSRRRS 1131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo81F	NP_001303492.1	Motor_domain	23..673	CDD:473979	230/705 (33%)
		MyTH4	1091..1194	CDD:459939
		FERM_F1_DdMyo7_like	1198..1299	CDD:340728
		B41	1202..1419	CDD:214604
		PH-like	1415..1523	CDD:473070
		MyTH4	1664..1771	CDD:459939
		FERM_F1_DdMyo7_like	1775..1880	CDD:340728
		B41	1781..1992	CDD:214604
		PH-like	1988..2076	CDD:473070
Myo3b	NP_796350.2	STKc_myosinIIIB_N	20..310	CDD:270808
		MYSc_Myo3	373..1062	CDD:276830	230/706 (33%)