Protein Alignment Pzl and AT2G48060

DIOPT Version :9

• Sequence 1: NP_001303493.1
• Gene: Pzl / 26067051
• FlyBaseID: FBgn0267430
• Length: 2326
• Species: Drosophila melanogaster
• Sequence 2: NP_001323909.1
• Gene: AT2G48060 / 819418
• AraportID: AT2G48060
• Length: 2485
• Species: Arabidopsis thaliana
• Alignment Length: 2686
• Identity: 538/2686 - (20%)
• Similarity: 951/2686 - (35%)
• Gaps: 835/2686 - (31%)

  Fly     8 IITRIFLPLTLILVSLVR----------------------PVGLSYF------------------ 32
            |.:.:||.|..|::|.||                      |...|:|
plant   252 ICSGLFLVLFYIMLSYVRSDLEDMDFIMSTSENNLAERLLPPKYSFFIRESRAGVRHTNVLLRGA 316

  Fly    33 ----YLLTFFLSPWLLQSNSLKQRTFLNVFIIFLCVLSTFGIVGHIIFNLINLF----------- 82
                :.:.||...:.:   ||...:|.:.....||.......||:||:...:||
plant   317 VFKTFSINFFTYGFPV---SLFALSFWSFHFASLCAFGLLAYVGYIIYAFPSLFQLHRLNGLLLV 378

  Fly    83 FVDLSSKNSFSFILRQFGFLYFKG------LSFVSIAHWILPDIIV--------------LLNTI 127
            |:.|.:.:::.|.: .|.||..|.      ...|.:.|:.:|...:              |:|..
plant   379 FILLWAVSTYIFNV-AFSFLNTKVGKDMQIWEMVGLWHYTIPGFFLLAQFGLGMLVALGNLVNNS 442

  Fly   128 VFFIFSE--IKYKREKRVIQNDDDVFYKKSKELKGALKVAEINRVLIIVYIRSVLKTSLIFSLIV 190
            ||...||  .:...|:..::.|::                  .:||::..|...|:......::.
plant   443 VFLYLSEESSRSSNERSYVEADEE------------------TKVLVVATIAWGLRKCSRAIMLA 489

  Fly   191 LYFAATLRPSLPGSLY---FCMFIIAGSYWALFRQRKMYYSVIFMIVALLVHITCIFAYQLPVLQ 252
            |.|...::|....::|   |.|::::.:.     .||:..|:|.:..   ||...::..::.::.
plant   490 LIFLIAMKPGFFHAVYVIFFLMYLLSHNI-----NRKIRKSLILLCE---VHFALLYILEIDLVS 546

  Fly   253 NTINCDKLWTRLMGMEVLIRLN--KDNRNGKILELNPKLNLDSYLSPIALMLAYFATTLSLINRS 315
            |::..:...:|    |||.:|.  :...:...||             |||:..:.|     |:..
plant   547 NSLKQEGSASR----EVLFQLGLLRSESSWDFLE-------------IALLACFCA-----IHNH 589

  Fly   316 QYEISFN---TIRMNLGPKSNSIYDNIQPSNEENEEISIFTEPSMLEQFFYIVYELSSFVYKNSY 377
            .:|:.|:   .:|....|...  :..::....::..:|:::.||            ||:...|:.
plant   590 GFEVLFSFSAIVRHTPSPPIG--FSILKAGLNKSVLLSVYSSPS------------SSYSQDNTT 640

  Fly   378 ILLNIIMMIWSIVYHSWLTFVLLIWANILWMIPNQRRSMMRS-SLFVVFYSQILLLAQYIYGMNL 441
            ...:|                    |:.|..|..:..||.|| ..::.|.:  :|::.|:...|
plant   641 YERHI--------------------ASFLSAIGQKFLSMYRSCGTYIAFIT--ILISVYLVKPN- 682

  Fly   442 YESELPTKVTSCGLNLEQIGFVHPQSKDSLPWIPLTVKTVFLFVFWVTSRQYFREISLDRQQSDL 506
            |.|               .|:                  :||.:.|:|.||.|.|
plant   683 YVS---------------FGY------------------IFLLLLWITGRQLFEE---------- 704

  Fly   507 LQQIFATHRSRSEHLLSKKSQTPQIFIYILKSTSHFITRIWMWL-----LIFLIFLCAMIDRTMT 566
                  |.|                             |:|..|     |:|:...|
plant   705 ------TKR-----------------------------RLWFPLKAYAVLVFMFIYC-------- 726

  Fly   567 GIRICYMSLFLLFLMVFQMSLQLWIRFLYGYWIFLIFYAMTILTAIYTYQFDHFDYYWEKFLKVH 631
                  :|.|        :|||||   |.|: |.|.||..      |..:....|..||..
plant   727 ------LSSF--------VSLQLW---LSGF-IDLYFYLG------YNSKAPLLDNVWESL---- 763

  Fly   632 STLQCDIGLRRYQTKDLFLHLLIPTLTVIFTVVQLHYFHRRFVESVRRPRSTEGQNFHLAPNAET 696
                                       .:..|:||:.:.||             |:.|..|...:
plant   764 ---------------------------AVLIVMQLYSYERR-------------QSGHYIPGQSS 788

  Fly   697 RASQKTLDIHRQSWKVFFDAGYENVRAKGRQLFNPGKIVAW-KFLEMHMIKTVTLASFYCAISEI 760
                                           |.:||....: :||..|..|.:..|.||.::|.|
plant   789 -------------------------------LLHPGVFGFFERFLAWHGQKILFAALFYASLSPI 822

  Fly   761 CFLNLFLVILSLLGICGNRFLRRVIFRAVTFWI--SLLVLMKMIYQI-----------KYLDQSH 812
            .... |:.:|.|: || ..|.:.....:.:|.|  ..||..:.::|:           ||.:.|.
plant   823 SVFG-FVYLLGLV-IC-TTFPKSSSIPSKSFLIYTGFLVSAEYLFQLWGMQAQMFPGQKYAELSF 884

  Fly   813 Y--------------NFKCGNVTV--------NFAEWMGLRKTGTVFGVHLRYISSYIIYMIL-- 853
            |              :...|.|.|        |...|  |.:|..:..:..:|.....:::..
plant   885 YLGLRVYEPGFWGIESGLRGKVLVVAACTLQYNVFRW--LERTSGLTVIKGKYEEPCPLFVSAED 947

  Fly   854 --------------TSLHAVVKLRD---------------------------------------- 864
                          ::.||.:.::.
plant   948 TTASVSSSNGENPSSTDHASISMKQGEATSNSWPFFSPRGNQGAGFLHPKTGGSESGSSRKFSFG 1012

  Fly   865 HL---IRYSTHKQKDTKLLFPDITRQDAERDFPGLLKYVLNYG----YFKFGFEITMIGLMSTIA 922
            |.   |:.| |:....::|.....|.:.:::   |||..|.:.    :..:|.||.||.|:....
plant  1013 HFWGSIKES-HRWNRRRILALKKERFETQKN---LLKIYLKFWIENMFNLYGLEINMIALLLASF 1073

  Fly   923 HRRDLFALTYLIWLVLLLCLSRFRCARIWEMLQLYFVLSIFVQYVYLLN--FP----PNLCNVIS 981
            ...:..::.|:..|...:.|.|....::|.::...|...:.::||...|  .|    |:..:|..
plant  1074 ALLNAISMVYIALLAACVLLRRRVIQKLWPVVVFLFASILAIEYVATWNSFLPSDQAPSETSVHC 1138

  Fly   982 YNSLWSIS------------GSKNYTNRSNIMFDYIVLLLISRQRKSFRVEMRHINDLSYRGGVN 1034
            :: .|||:            |.:  .:....:..|.|:.:::    .|::...||:..|     .
plant  1139 HD-CWSIAALYFKFCRECWLGVR--VDDPRTLISYFVVFMLA----CFKLRADHISSFS-----E 1191

  Fly  1035 TNVVHNI---AKLGHVY----FENPTHDFCTYVRNYADVLKTAIFFSFFWITLAIVFLGGVCSTD 1092
            ::..|.:   .|...|:    ||  |....|.:    |.|:...:.....:.|.::.:.|....|
plant  1192 SSTYHQMKSQRKNSFVWRDLSFE--TKSMWTVL----DYLRLYCYVHLLDVVLILILITGTLEYD 1250

  Fly  1093 ILSLGYIIFALIFLLQGSEIYLQNIHFIICRWNCLIAF-NIFNIIVKVAIIVLEGTINLEHKSIL 1156
            ||.|||:.|||:|.....|        |:.:.|.:..| .::|.::
plant  1251 ILHLGYLAFALVFARMRLE--------ILKKKNKIFRFLRVYNFVL------------------- 1288

  Fly  1157 SIVFNVMHQTAPCENIMDGKFFEINEISE----KKYCYGPSDMIFKNTLVWHAIIFSFVVFQYRI 1217
             |:|::.:|:....|..|||...::.|.|    .||.|| ..:..::.|| ..|||..|..|..:
plant  1289 -IIFSLAYQSPFVGNFNDGKCETVDYIYEVIGFYKYDYG-FRITARSALV-EIIIFMLVSLQSYM 1350

  Fly  1218 FGSYYFCHVIMDTQANTILASRGAAIIENLHYKQIYDRRKNEQSVLERVKMKMERIRITNRRHQK 1282
            |.|..|.:|....:|..|     .||:.....|.   .||.||  |::::...|:.|..|
plant  1351 FSSQEFDYVSRYLEAEQI-----GAIVREQEKKA---ARKTEQ--LQQIREAEEKKRQRN----- 1400

  Fly  1283 QATGLDFQPHKPPSSIIHVHYRAEEKSKLKTLNNEFLTTIKQAERDTYF------SRSLKPRRRD 1341
                  .|..|..|.::::      :.:|..:|:           |:.|      :..|: ||:.
plant  1401 ------LQVEKMKSEMLNL------RVQLHRMNS-----------DSNFGVASPRTEGLR-RRKS 1441

  Fly  1342 LSLHPHAVRTGDYYMFNELD------DDDDLDVYEEYDFLEKEDVRARQMRQSLRSRASNYNRSK 1400
            ..|.|.:.....     |:|      ::..:|...:|.| |..:.......::|.|...::..|.
plant  1442 PYLIPDSGAASP-----EIDGVVHRKEEQPIDEDSQYPF-EAHEFPVSTTPEALDSPEYSFGASP 1500

  Fly  1401 SFLNDENSDTDTKKLETHPVIILTSELIVLLTFRLNRLSKNFRFVHKMLSAEKKKLQNISIMNRL 1465
            ..:.:...|.|...:|.                  .|..|:....:.::||.:.....:|.:..:
plant  1501 CEITEVQQDLDVMSMER------------------ERKQKSEGKENPLISAVQLIGDGVSQVQFI 1547

  Fly  1466 GLSNTAAMFKFLNKSLNNKVIKEAGSY-------YVSQDNDFTTLDHNDFVQ------------- 1510
            |......:..|||.|..|....|..|.       ..||....|..:.:..:|
plant  1548 GNQAVNNLVNFLNISPENSDTNEQSSVDDEVYDEMESQKRKHTPFERSTSLQSDRSSDGTSFQIG 1612

  Fly  1511 -MLIALWYALIANTETICY---LVVFLNQAANSSVISLPMPFL-VLCWGALTLPRPSKTFWVTLI 1570
             :...:|..:.:|.:.:||   ::.||...:..|::.|...|| .||    ....|:..|||.::
plant  1613 RIFRHIWSRMQSNNDIVCYCCFIIAFLWNFSLLSMVYLAALFLYALC----VHTGPTHIFWVIML 1673

  Fly  1571 TYN-----LTMIFVKSIMHQRVLLDQQLVSRSNSLSFEL-IMKRGRAVYDL-LLLVVLFW--HQY 1626
            .|.     |..::...|.|..:.:|..|:   :.|.|.. .:|....|..| |.|:.:|.  ...
plant  1674 MYTEIYILLQYLYQIIIQHCGLSIDAPLL---HELGFPTQRIKSSFVVSSLPLFLIYIFTLIQSS 1735

  Fly  1627 MLKKQGIW-------------------TIQRTNSELLLLEKK---------RNHYKRSFSKER-- 1661
            :..|.|.|                   |..|.:..:|.:.||         |:.|:...|..|
plant  1736 ITVKDGDWVPSADFTSRRNARGSQKDLTRIRLSQRILDVFKKLRDSAKLVIRSIYRYWISLTRGA 1800

  Fly  1662 ----------------------PENI----RKLLR-------EEGGGE---QVKAVRPNAIEFKR 1690
                                  ||.:    .:|||       |:|..:   ....|...:||...
plant  1801 ESPPYFVQVTMDVHMWPEDGIQPERVECRMNQLLRLVHNERCEKGNPDLCPYSSRVHVQSIERST 1865

  Fly  1691 EMDDILLPALENKYVYQN---IESEYY-------------RKAMQGLANKGGLLSGFRKFFLALR 1739
            |..:..|..||.:|....   ..:|:|             |||......:|   :||....|::.
plant  1866 ETPNEALVVLEVEYASPTNGCSSAEWYKSLTPASDVAKEIRKAQHSGLGEG---TGFPYPILSVI 1927

  Fly  1740 HKSRLSTDVYTLLFLCDFISFFILLFGFPKFVYRYKYSTSVLETYIQGNKVPFTFLLMLIVQFIT 1804
            ...:..||:|..:|..|.|.||::...:...:   |..:..::.|...::.||.|:::|:|.|..
plant  1928 GGGKRDTDLYAYIFGADLIVFFLVAIFYQSVI---KNKSEFIDVYQLEDQFPFDFVIILMVIFFL 1989

  Fly  1805 IVTERAIYLRKALIYKIFFHFISVLGIHIWMFFLVPYITS------HSFGETAPVLFYLIKCLHM 1863
            ||.:|.|||......|:.::..|::   ::.:.:..|..|      |:.|....::| |.|.:.:
plant  1990 IVVDRVIYLCSFATGKVVYYLFSLI---LFTYAVTEYAWSIYPTQQHAAGLALRIIF-LAKAMSL 2050

  Fly  1864 LLSAYQIRCGYPKR--ILGNVFTKGYSLANYIAFKIYMEIPFLYILRTMLDWVCIDTTLTVMEWI 1926
            .|.|.|||.|.|.:  :.....|...|..||..:::|..:||||.||.:|||.|..|:||:.:|:
plant  2051 ALQAIQIRYGLPHKSTLYRQFLTSEVSRINYYGYRLYRALPFLYELRCVLDWSCTATSLTMYDWL 2115

  Fly  1927 KMEDIFQSVFIVRCYRQMDTDFPVL------RGEPKALYSKLLIGGTIILILIALIWSPLFLFAL 1985
            |:||:..|:::|:|    ||   ||      .||.:...:|...|..:..||:.:||:|:.:::.
plant  2116 KLEDVNASLYLVKC----DT---VLNRATHKHGEKQTKMTKCCNGICLFFILLCVIWAPMLMYSS 2173

  Fly  1986 VGTVGKPNIPQKADITV-------KINHYEPIYVSQSNSDILQFSNSDFQKLTNHIILDNYASDS 2043
            .......|..:.|.:.:       |:..|:.....:.:.|.:...            ||..:...
plant  2174 GNPTNIANPIKDASVQIDLKTVGGKLTLYQTTLCERISGDNIDLG------------LDLGSQSF 2226

  Fly  2044 MMLYDAVDVTAIKFYENSISLWNMPPPDKERLLHDLSNGETLDIHLTLTLKCNLT--PEAVIYET 2106
            :..|:..|:..|....::..||.:|.....|.:..|.....:||..|..|..:..  .|.|.||.
plant  2227 LPTYNKNDIQLICCQADASVLWLVPDTVVTRFIQSLDWDTDMDITFTWVLNRDRPKGKETVKYER 2291

  Fly  2107 TYTLTENKVHTRDKL-------IRLMSNNFSNEKVIIPNILPKFITVQRQQANAKFIKDYDGKFN 2164
            :.          |.|       |:::.|. |.:...:.|:.|||..| ....:.:..:|...:.:
plant  2292 SV----------DPLDLPKRSDIQMVLNG-SMDGFRVHNLYPKFFRV-TGSGDVRSFEDQTDEVS 2344

  Fly  2165 RPIILTKIGKSQVYWWEMNDYCNDRFYTEILSALPLSNCE--NGVVLYVFNDKSFPSAM--SFLE 2225
            ..|::......  :||..::         :.::..:|.||  :|.|..:.::::.|...  ..|.
plant  2345 ADILINHANFK--WWWSFHN---------LKASENISACEGMDGPVAIIMSEETPPQGFLGDTLS 2398

  Fly  2226 KTGIIGLYTTFVYVVSRIIRSLIANNHRRIMFEDLPYVDRVLKLCTDIYLVRETQEYRLEEDLYG 2290
            |..|.|||.|||..|.|.||...::...||.:|:||..||::.:|.|:|..|...|..:||.||.
plant  2399 KFSIWGLYITFVLAVGRFIRLQCSDLRMRIPYENLPSCDRLIAICEDLYAARAEGELGVEEVLYW 2463

  Fly  2291 KLIFLYRSPETLIKWTRFKED 2311
            .|:.:||||..|:::|:...|
plant  2464 TLVKIYRSPHMLLEYTKLDYD 2484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pzl	NP_001303493.1	PIEZO	<1201..1388	CDD:292539	42/198 (21%)
		Piezo_RRas_bdg	1901..2308	CDD:288978	112/432 (26%)
AT2G48060	NP_001323909.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1571
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	294	1.000	Inparanoid score	I816
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001637
OrthoInspector	1	1.000	-	-		otm3283
orthoMCL	1	0.900	-	-		OOG6_102664
Panther	1	1.100	-	-	O	PTHR13167
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1528
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.050