DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-lambda and zgc:152904

DIOPT Version :9

Sequence 1:	NP_001334747.1	Gene:	DIP-lambda / 26067049	FlyBaseID:	FBgn0267428	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001070212.1	Gene:	zgc:152904 / 767777	ZFINID:	ZDB-GENE-060929-856	Length:	809	Species:	Danio rerio

Alignment Length:	460	Identity:	103/460 - (22%)
Similarity:	177/460 - (38%)	Gaps:	82/460 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KCHAVAHIHGKGESEEID-------PQFLA---KLSNTTVPIGRDISFTCVVDNLGHYRVAWIKS 86
            :|.  |.:..:||.:..|       |..|:   :..|.|......::||||.......:|.|...
Zfish   154 RCE--ARVEARGEIDFRDIVVQVNVPPVLSVPQQSFNATADYQESVTFTCVTSGSPDPQVTWYWK 216

  Fly    87 DSKAILGIHTHMVSLNPRLSVTHNGHNTWKLHISRVQINDSGSYMCQVNTDPMKSLSG-YLDVVV 150
             ..||  .|:....||     |.||..: .|.:..::..|.|.|||:.:.....|.|. :|.|.|
Zfish   217 -GHAI--EHSEQYVLN-----TMNGGKS-TLTVKNIKQTDGGPYMCRASNKAGSSESQLFLKVFV 272

  Fly   151 PPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREAGKEIILRTDG-RDKTGFKSVEG 214
            .|.|.     ...:....||.:..:.|:..|.|.|::.|||.:.....  ||| :.|.|...|.|
Zfish   273 QPHIT-----QLRNVTAVEGSAAMISCTAEGEPLPEISWRRASDGHSF--TDGEKSKDGRVEVRG 330

  Fly   215 ER----LVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKAISQLVGAPVEREVTLEC 275
            ..    |.::.||.||.|.::|.|.:.|.......| :.:.::|..:....:..:.....|.:.|
Zfish   331 RHGKSMLTISGVQLSDWGRFDCEALSRIGGHQKSMF-LDIEYAPKFQTNQSIFYSWEGNPVNISC 394

  Fly   276 IVEVFPKPLNGWYR------SEG--NIKLHNGNKYNISEEVINIYTWHLNLTIRHLTKSDFGTYS 332
            .|:..|.....|.|      |:|  ||::|:.:..::             |.:..::..|||.|:
Zfish   395 EVKSNPAATMLWRRERFTISSQGTSNIRIHSTDGRSL-------------LEVTPVSDRDFGRYN 446

  Fly   333 CSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTGKSRRKHPASHKKGLNE--------VLRF 389
            |::.|.:|     .|.||..|......:....::.|..|:|....|..|..:.        ::.:
Zfish   447 CTARNNIG-----ARYQEFILAQADVPSSPYSVRMTAVSQRMATVSFMKPDSHGGVPISFYIINY 506

  Fly   390 QETHFANQIQQENEDHNEGFDLLKFTNSENSNIVLESGHINSMINKEDVNIYHPKQYGQEKTNKP 454
            ::|..|.:.:...            |:...:.:||.|...|:..... |:..:.|..|:....:.
Zfish   507 RDTSSAQEWRSAR------------THGVQTAVVLTSLEPNTTYEVR-VSAVNGKGQGEFSHTES 558

  Fly   455 SGTIP 459
            ..|:|
Zfish   559 FQTLP 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-lambda	NP_001334747.1	None
zgc:152904	NP_001070212.1	Ig	1..81	CDD:299845
		IG_like	2..80	CDD:214653
		IGc2	97..158	CDD:197706	1/5 (20%)
		Ig	177..273	CDD:299845	28/104 (27%)
		I-set	184..270	CDD:254352	25/94 (27%)
		Ig	272..369	CDD:299845	29/104 (28%)
		I-set	274..367	CDD:254352	28/100 (28%)
		IG_like	385..462	CDD:214653	22/94 (23%)
		IGc2	386..454	CDD:197706	18/80 (23%)
		FN3	468..561	CDD:238020	15/105 (14%)
		fn3	<591..650	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010