Protein Alignment DIP-lambda and NTM

DIOPT Version :10

• Sequence 1: NP_001334747.1
• Gene: DIP-lambda / 26067049
• FlyBaseID: FBgn0267428
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001338930.1
• Gene: NTM / 50863
• HGNCID: 17941
• Length: 367
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 111/395 - (28%)
• Similarity: 162/395 - (41%)
• Gaps: 79/395 - (20%)

  Fly     5 KTARIKMYNGTLACSIAFILIKAITITKCHAVAHIHG----KGESEEIDPQFLAKLSNTTVPIGR 65
            ||.:.||:|     ||::.:...:.     |:....|    .|     |..|...:.|.||..|.
Human     2 KTIQPKMHN-----SISWAIFTGLA-----ALCLFQGVPVRSG-----DATFPKAMDNVTVRQGE 51

  Fly    66 DISFTCVVDNLGHYRVAWIKSDSKAILGIHTHMVSLNPRLSVTHNGHNTWKLHISRVQINDSGSY 130
            ..:..|.:|| ...||||:  :...||........|:||:.:..|....:.:.|..|.:.|.|.|
Human    52 SATLRCTIDN-RVTRVAWL--NRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPY 113

  Fly   131 MCQVNTD--PMKSLSGYLDVVVPPDILNHPEHNPEDGVCQEGGSISLMCSVTGVPRPKVLWRREA 193
            .|.|.||  | |:...:|.|.|.|.|:    ....|....||.:|||.|..||.|.|.|.||..:
Human   114 TCSVQTDNHP-KTSRVHLIVQVSPKIV----EISSDISINEGNNISLTCIATGRPEPTVTWRHIS 173

  Fly   194 GKEIILRTDGRDKTGFKSVEGERLVLTNVQRSDMGGYNCIASNGIPPSVSKRFNVYVNFSPTVKA 258
            .|.:          ||.| |.|.|.:..:.|...|.|.|.|||.:...|.:|..|.||:.|.:..
Human   174 PKAV----------GFVS-EDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISE 227

  Fly   259 ISQLVGAPVEREVTLECIVEVFPKPLNGWYRSEGNIKLHNGNK---------------YNISEEV 308
             ::..|.||.::.||:|.....|.....||:.:.  :|..|.|               :|:||.
Human   228 -AKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDK--RLIEGKKGVKVENRPFLSKLIFFNVSEH- 288

  Fly   309 INIYTWHLNLTIRHLTKSDFGTYSCSSVNALGKSESLIRLQELRLPPKLTTTPTPHMQTTGKSRR 373
                              |:|.|:|.:.|.||.:.:.|.|.||..|  .::|....::||..:..
Human   289 ------------------DYGNYTCVASNKLGHTNASIMLFELNEP--TSSTLLQEVKTTALTPW 333

  Fly   374 KHPAS 378
            |.|.:
Human   334 KGPGA 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-lambda	NP_001334747.1	IG_like	57..150	CDD:214653	30/94 (32%)
		Ig strand B	67..71	CDD:409353	0/3 (0%)
		Ig strand E	115..119	CDD:409353	0/3 (0%)
		Ig strand F	129..134	CDD:409353	2/4 (50%)
		Ig	153..250	CDD:472250	32/96 (33%)
		Ig strand B	173..177	CDD:409353	3/3 (100%)
		Ig strand C	186..190	CDD:409353	1/3 (33%)
		Ig strand E	204..219	CDD:409353	6/14 (43%)
		Ig strand F	229..234	CDD:409353	2/4 (50%)
		Ig strand G	243..246	CDD:409353	0/2 (0%)
		IG_like	271..349	CDD:214653	20/92 (22%)
		Ig strand B	271..275	CDD:409353	2/3 (67%)
		Ig strand C	284..288	CDD:409353	0/3 (0%)
		Ig strand E	308..320	CDD:409353	0/11 (0%)
		Ig strand F	330..335	CDD:409353	2/4 (50%)
NTM	NP_001338930.1	Ig	44..132	CDD:472250	29/91 (32%)
		Ig strand B	53..57	CDD:409353	0/3 (0%)
		Ig strand C	65..69	CDD:409353	3/3 (100%)
		Ig strand E	98..102	CDD:409353	0/3 (0%)
		Ig strand F	112..117	CDD:409353	2/4 (50%)
		Ig strand G	125..128	CDD:409353	0/2 (0%)
		Ig_3	136..205	CDD:464046	28/83 (34%)
		Ig	223..307	CDD:472250	23/105 (22%)
		Ig strand B	239..243	CDD:409353	2/3 (67%)
		Ig strand C	252..256	CDD:409353	0/3 (0%)
		Ig strand E	278..282	CDD:409353	0/3 (0%)
		Ig strand F	292..297	CDD:409353	2/4 (50%)